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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2017 Volume 51 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Connexin 43 in the development and progression of breast cancer: What's the connection? (Review)

Stephanie L. Phillips, Carly Bess Williams, Joelle N. Zambrano, Christina J. Williams, Elizabeth S. Yeh
Pages: 1005-1013
Published online on: 01 September 2017

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Review

Trophic and neurotrophic factors in human pituitary adenomas (Review)

Marialuisa Spoletini, Samanta Taurone, Mario Tombolini, Antonio Minni, Giancarlo Altissimi, Venceslao Wierzbicki, Felice Giangaspero, Pier Paolo Parnigotto, Marco Artico, Lia Bardella, Enzo Agostinelli, Francesco Saverio Pastore
Pages: 1014-1024
Published online on: 05 September 2017

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Review Open Access

Rho GTPases as therapeutic targets in cancer (Review)

G. A. Cardama, N. Gonzalez, J. Maggio, P. Lorenzano Menna, D. E. Gomez
Pages: 1025-1034
Published online on: 09 August 2017

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Article Open Access

Phospho-valproic acid inhibits pancreatic cancer growth in mice: enhanced efficacy by its formulation in poly-(L)-lactic acid-poly(ethylene glycol) nanoparticles Corrigendum in /10.3892/ijo.2018.4584

George Mattheolabakis, Ruixue Wang, Basil Rigas, Gerardo G. Mackenzie
Pages: 1035-1044
Published online on: 25 August 2017

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Article Open Access

FoxM1 overexpression promotes cell proliferation and migration and inhibits apoptosis in hypopharyngeal squamous cell carcinoma resulting in poor clinical prognosis

Yan Chen, Yifei Liu, Haosheng Ni, Chuanjin Ding, Xiaobo Zhang, Zhenxin Zhang
Pages: 1045-1054
Published online on: 09 August 2017

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Article Open Access

YAP signaling in gastric cancer-derived mesenchymal stem cells is critical for its promoting role in cancer progression

Zhaoji Pan, Yiqing Tian, Bin Zhang, Xu Zhang, Hui Shi, Zhaofeng Liang, Peipei Wu, Rong Li, Benshuai You, Lunyu Yang, Fei Mao, Hui Qian, Wenrong Xu
Pages: 1055-1066
Published online on: 23 August 2017

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Article Open Access

Prediction of radiosensitive patients with gastric cancer by developing gene signature

Jin Zhou, Xiaoyu Wu, Gang Li, Xin Gao, Min Zhai, Weichang Chen, Huagang Hu, Zaixiang Tang
Pages: 1067-1076
Published online on: 30 August 2017

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Article Open Access

Nano Let‑7b sensitization of eliminating esophageal cancer stem‑like cells is dependent on blockade of Wnt activation of symmetric division

Yamei Pang, Jian Liu, Xiang Li, Yiwen Zhang, Boxiang Zhang, Jing Zhang, Ning Du, Chongwen Xu, Rui Liang, Hong Ren, Shou-Ching Tang, Xin Sun
Pages: 1077-1088
Published online on: 29 August 2017

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Article Open Access

Gold-chrysophanol nanoparticles suppress human prostate cancer progression through inactivating AKT expression and inducing apoptosis and ROS generation in vitro and in vivo

Li Lu, Ke Li, Yun-Hua Mao, Hu Qu, Bing Yao, Wen-Wen Zhong, Bo Ma, Zhong-Yang Wang
Pages: 1089-1103
Published online on: 10 August 2017

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Article Open Access

SERP1 is a novel marker of poor prognosis in pancreatic ductal adenocarcinoma patients via anti-apoptosis and regulating SRPRB/NF-κB axis

Qiang Ma, Xiuxiu Wu, Jing Wu, Zhiyong Liang, Tonghua Liu
Pages: 1104-1114
Published online on: 31 August 2017

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Article Open Access

TUG1 promotes osteosarcoma tumorigenesis by upregulating EZH2 expression via miR-144-3p

Jiaqing Cao, Xinyou Han, Xin Qi, Xiangyun Jin, Xiaolin Li
Pages: 1115-1123
Published online on: 30 August 2017

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Article Open Access

Effect of low- and high-linear energy transfer radiation on in vitro and orthotopic in vivo models of osteosarcoma by activation of caspase-3 and -9

Eun Ho Kim, Mi-Sook Kim, Kyung-Hee Lee, Sei Sai, Youn Kyoung Jeong, Jae-Soo Koh, Chang-Bae Kong
Pages: 1124-1134
Published online on: 25 August 2017

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Article Open Access

Expression of Wnt3a in hepatocellular carcinoma and its effects on cell cycle and metastasis

Caijie Lu, Yifeng He, Juan Duan, Yongguang Yang, Chunqiang Zhong, Jian Zhang, Weiguo Liao, Xiaojie Huang, Runzhi Zhu, Mingyi Li
Pages: 1135-1145
Published online on: 01 September 2017

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Article

Disrupting mitochondrial Ca2+ homeostasis causes tumor-selective TRAIL sensitization through mitochondrial network abnormalities

Yohei Ohshima, Natsuhiko Takata, Miki Suzuki-Karasaki, Yukihiro Yoshida, Yasuaki Tokuhashi, Yoshihiro Suzuki-Karasaki
Pages: 1146-1158
Published online on: 11 August 2017

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Article

Cx32 suppresses extrinsic apoptosis in human cervical cancer cells via the NF‑κB signalling pathway

Yongchang Lai, Lixia Fan, Yifan Zhao, Hui Ge, Xue Feng, Qin Wang, Xiaomin Zhang, Yuexia Peng, Xiyan Wang, Liang Tao
Pages: 1159-1168
Published online on: 29 August 2017

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Article

Luteolin induces apoptotic cell death via antioxidant activity in human colon cancer cells

Kyoung Ah Kang, Mei Jing Piao, Yea Seong Ryu, Yu Jae Hyun, Jeong Eon Park, Kristina Shilnikova, Ao Xuan Zhen, Hee Kyoung Kang, Young Sang Koh, Yong Joo Jeong, Jin Won Hyun
Pages: 1169-1178
Published online on: 02 August 2017

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Article

Expression of carbonic anhydrase IX is associated with poor prognosis through regulation of the epithelial‑mesenchymal transition in hepatocellular carcinoma

Satoshi Hyuga, Hiroshi Wada, Hidetoshi Eguchi, Toru Otsuru, Yoshifumi Iwgami, Daisaku Yamada, Takehiro Noda, Tadafumi Asaoka, Koichi Kawamoto, Kunihito Gotoh, Yutaka Takeda, Masahiro Tanemura, Koji Umeshita, Yuichiro Doki, Masaki Mori
Pages: 1179-1190
Published online on: 22 August 2017

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Article

GPER promotes tamoxifen-resistance in ER+ breast cancer cells by reduced Bim proteins through MAPK/Erk-TRIM2 signaling axis

Heng Yin, Qing Zhu, Manran Liu, Gang Tu, Qing Li, Jie Yuan, Siyang Wen, Guanglun Yang
Pages: 1191-1198
Published online on: 05 September 2017

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Article

Establishment of two ovarian cancer orthotopic xenograft mouse models for in vivo imaging: A comparative study

Jing Guo, Jing Cai, Yunxia Zhang, Yapei Zhu, Ping Yang, Zehua Wang
Pages: 1199-1208
Published online on: 04 September 2017

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Article

Activation of the ROCK1/MMP-9 pathway is associated with the invasion and poor prognosis in papillary thyroid carcinoma

Dingyuan Luo, Haibo Chen, Xiaojuan Li, Penghui Lu, Miaoyun Long, Xinzhi Peng, Shaojian Lin, Langping Tan, Yue Zhu, Nengtai Ouyang, Honghao Li
Pages: 1209-1218
Published online on: 23 August 2017

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Article

Silibinin suppresses bladder cancer cell malignancy and chemoresistance in an NF-κB signal-dependent and signal-independent manner

Yi Sun, Zhenfeng Guan, Wencai Zhao, Yazhuo Jiang, Qing Li, Yongyi Cheng, Yonggang Xu
Pages: 1219-1226
Published online on: 02 August 2017

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Article

Measuring the response of human head and neck squamous cell carcinoma to irradiation in a microfluidic model allowing customized therapy

Ramsah Cheah, Rishi Srivastava, Nicholas D. Stafford, Andrew W. Beavis, Victoria Green, John Greenman
Pages: 1227-1238
Published online on: 05 September 2017

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Article

Novel crosstalk between KLF4 and ZEB1 regulates gemcitabine resistance in pancreatic ductal adenocarcinoma Corrigendum in /10.3892/ijo.2020.5157

Zhiyi Wang, Yuan Chen, Yanliang Lin, Xinxing Wang, Xianping Cui, Zhenhai Zhang, Guozhe Xian, Chengkun Qin
Pages: 1239-1248
Published online on: 22 August 2017

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Article Open Access

Melatonin potentiates the antitumor effect of curcumin by inhibiting IKKβ/NF-κB/COX-2 signaling pathway

Sandeep Shrestha, Jiabin Zhu, Qi Wang, Xiaohui Du, Fen Liu, Jianing Jiang, Jing Song, Jinshan Xing, Dongdong Sun, Qingjuan Hou, Yulin Peng, Jun Zhao, Xiuzhen Sun, Xishuang Song
Pages: 1249-1260
Published online on: 22 August 2017

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Article

Identification of WISP1 as a novel oncogene in glioblastoma

Di Jing, Qian Zhang, Haiming Yu, Yajie Zhao, Liangfang Shen
Pages: 1261-1270
Published online on: 05 September 2017

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Article

PRL-3 improves colorectal cancer cell proliferation and invasion through IL-8 mediated glycolysis metabolism

Heyang Xu, Yujie Zeng, Lu Liu, Qian Gao, Shaowen Jin, Qiusheng Lan, Wei Lai, Xingxi Luo, Heng Wu, Yongliang Huang, Zhonghua Chu
Pages: 1271-1279
Published online on: 02 August 2017

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Article

Identification of novel genetic etiology and key molecular pathways for seminoma via network-based studies

Yuanlei Chen, Chao Qi, Liqun Xia, Gonghui Li
Pages: 1280-1290
Published online on: 04 August 2017

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Article

Synergistic inhibitory effects on hepatocellular carcinoma with recombinant human adenovirus Aspp2 and oxaliplatin via p53-independent pathway in vitro and in vivo

Xiaoni Liu, Jianji Xu, Shuang Wang, Xiaoxiao Yu, Boxin Kou, Mengyin Chai, Yunjin Zang, Dexi Chen
Pages: 1291-1299
Published online on: 29 August 2017

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Article

Expression of periostin in breast cancer cells

Katarzyna Ratajczak-Wielgomas, Jedrzej Grzegrzolka, Aleksandra Piotrowska, Rafal Matkowski, Andrzej Wojnar, Janusz Rys, Maciej Ugorski, Piotr Dziegiel
Pages: 1300-1310
Published online on: 30 August 2017

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Article

Anoctamin5 regulates cell migration and invasion in thyroid cancer

Zhengyan Chang, Chunmiao Cai, Dongyan Han, Yaohui Gao, Qianyu Li, Lijin Feng, Wei Zhang, Jiayi Zheng, Jiaoying Jin, Huizhen Zhang, Qing Wei
Pages: 1311-1319
Published online on: 01 September 2017

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Article

Cooperative oncogenic effect and cell signaling crosstalk of co‑occurring HER2 and mutant PIK3CA in mammary epithelial cells

Lun Dong, Fanyan Meng, Ling Wu, Allison V. Mitchell, C. James Block, Bin Zhang, Douglas B. Craig, Hyejeong Jang, Wei Chen, Qifeng Yang, Guojun Wu
Pages: 1320-1330
Published online on: 30 August 2017

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Article

Ginkgetin induces G2-phase arrest in HCT116 colon cancer cells through the modulation of b‑Myb and miRNA34a expression

Yu-Jin Lee, Yeong-Rim Kang, So Young Lee, Yena Jin, Dong Cho Han, Byoung-Mog Kwon
Pages: 1331-1342
Published online on: 05 September 2017

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Article

APPL1 promotes the migration of gastric cancer cells by regulating Akt2 phosphorylation

Yingxun Liu, Chunli Zhang, Lingyu Zhao, Ning Du, Ni Hou, Tusheng Song, Chen Huang
Pages: 1343-1351
Published online on: 05 September 2017

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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