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International Journal of Oncology
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Review

The biology and function of extracellular vesicles in nasopharyngeal carcinoma (Review)

  • Authors:
    • Bo You
    • Ying Shan
    • Lili Bao
    • Jing Chen
    • Liu Yang
    • Qicheng Zhang
    • Wei Zhang
    • Zhenxin Zhang
    • Jie Zhang
    • Si Shi
    • Yiwen You
  • View Affiliations / Copyright

    Affiliations: Department of Otorhinolaryngology, Head and Neck Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China, Department of Neurosurgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China
  • Pages: 38-46
    |
    Published online on: November 10, 2017
       https://doi.org/10.3892/ijo.2017.4202
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Abstract

Extracellular vesicles are a heterogeneous group of membrane-enclosed vesicles, which play an important role in intercellular communication. Increasing number of studies have shown that tumor-derived extracellular vesicles might be involved in the transfer of oncogenic cargo (proteins, lipids, messenger RNA, microRNA, non-coding RNAs and DNA) through which cancer cells could shape the tumor microenvironment and influence tumor progression. Nasopharyngeal carcinoma-derived extracellular vesicles have also reported to facilitate tumor proliferation, metastasis and immune escape. Moreover, nasopharyngeal carcinoma-derived extracellular vesicles might serve as biomarkers for early diagnosis and therapeutic targets. The present review provides information on the biological and clinical significance of extracellular vesicles in tumors, especially in nasopharyngeal carcinoma.
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Copy and paste a formatted citation
Spandidos Publications style
You B, Shan Y, Bao L, Chen J, Yang L, Zhang Q, Zhang W, Zhang Z, Zhang J, Shi S, Shi S, et al: The biology and function of extracellular vesicles in nasopharyngeal carcinoma (Review). Int J Oncol 52: 38-46, 2018.
APA
You, B., Shan, Y., Bao, L., Chen, J., Yang, L., Zhang, Q. ... You, Y. (2018). The biology and function of extracellular vesicles in nasopharyngeal carcinoma (Review). International Journal of Oncology, 52, 38-46. https://doi.org/10.3892/ijo.2017.4202
MLA
You, B., Shan, Y., Bao, L., Chen, J., Yang, L., Zhang, Q., Zhang, W., Zhang, Z., Zhang, J., Shi, S., You, Y."The biology and function of extracellular vesicles in nasopharyngeal carcinoma (Review)". International Journal of Oncology 52.1 (2018): 38-46.
Chicago
You, B., Shan, Y., Bao, L., Chen, J., Yang, L., Zhang, Q., Zhang, W., Zhang, Z., Zhang, J., Shi, S., You, Y."The biology and function of extracellular vesicles in nasopharyngeal carcinoma (Review)". International Journal of Oncology 52, no. 1 (2018): 38-46. https://doi.org/10.3892/ijo.2017.4202
Copy and paste a formatted citation
x
Spandidos Publications style
You B, Shan Y, Bao L, Chen J, Yang L, Zhang Q, Zhang W, Zhang Z, Zhang J, Shi S, Shi S, et al: The biology and function of extracellular vesicles in nasopharyngeal carcinoma (Review). Int J Oncol 52: 38-46, 2018.
APA
You, B., Shan, Y., Bao, L., Chen, J., Yang, L., Zhang, Q. ... You, Y. (2018). The biology and function of extracellular vesicles in nasopharyngeal carcinoma (Review). International Journal of Oncology, 52, 38-46. https://doi.org/10.3892/ijo.2017.4202
MLA
You, B., Shan, Y., Bao, L., Chen, J., Yang, L., Zhang, Q., Zhang, W., Zhang, Z., Zhang, J., Shi, S., You, Y."The biology and function of extracellular vesicles in nasopharyngeal carcinoma (Review)". International Journal of Oncology 52.1 (2018): 38-46.
Chicago
You, B., Shan, Y., Bao, L., Chen, J., Yang, L., Zhang, Q., Zhang, W., Zhang, Z., Zhang, J., Shi, S., You, Y."The biology and function of extracellular vesicles in nasopharyngeal carcinoma (Review)". International Journal of Oncology 52, no. 1 (2018): 38-46. https://doi.org/10.3892/ijo.2017.4202
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