|
1
|
He C, Wu S, Gao A, Su Y, Min H, Shang ZF,
Wu J, Yang L, Ding WQ and Zhou J: Phosphorylation of ETS-1 is a
critical event in DNA polymerase iota-induced invasion and
metastasis of esophageal squamous cell carcinoma. Cancer Sci.
108:2503–2510. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Chen XX, Zhong Q, Liu Y, Yan SM, Chen ZH,
Jin SZ, Xia TL, Li RY, Zhou AJ, Su Z, et al: Genomic comparison of
esophageal squamous cell carcinoma and its precursor lesions by
multi-region whole-exome sequencing. Nat Commun. 8:5242017.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Hou Z, Abudureheman A, Wang L, Hasim A,
Ainiwaer J, Zhang H, Niyaz M, Upur H and Sheyhidin I: Expression,
prognosis and functional role of Thsd7a in esophageal squamous cell
carcinoma of Kazakh patients, Xinjiang. Oncotarget. 8:60539–60557.
2017.PubMed/NCBI
|
|
4
|
Qi Y, Cao KX, Xing FC, Zhang CY, Huang Q,
Wu K, Wen FB, Zhao S and Li X: High expression of MAGE-A9 is
associated with unfavorable survival in esophageal squamous cell
carcinoma. Oncol Lett. 14:3415–3420. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Chan CM, Lai KKY, Ng EKO, Kiang MN, Kwok
TWH, Wang HK, Chan KW, Law TT, Tong DK, Chan KT, et al: Serum
microRNA-193b as a promising biomarker for prediction of
chemoradiation sensitivity in esophageal squamous cell carcinoma
patients. Oncol Lett. 15:3273–3280. 2018.PubMed/NCBI
|
|
6
|
Shang M, Wang X, Zhang Y, Gao Z, Wang T
and Liu R: LincRNA-ROR promotes metastasis and invasion of
esophageal squamous cell carcinoma by regulating miR-145/FSCN1.
Onco Targets Ther. 11:639–649. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Deng XS, Meng X, Venardos N, Song R,
Yamanaka K, Fullerton D and Jaggers J: Autophagy negatively
regulates pro-osteogenic activity in human aortic valve
interstitial cells. J Surg Res. 218:285–291. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Gu Y, Gao L, Chen Y, Xu Z, Yu K, Zhang D,
Zhang G and Zhang X: Sanggenon C protects against cardiomyocyte
hypoxia injury by increasing autophagy. Mol Med Rep. 16:8130–8136.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Yu H, Qiu Y, Pang X, Li J, Wu S, Yin S,
Han L, Zhang Y, Jin C, Gao X, et al: Lycorine promotes autophagy
and apoptosis via TCRP1/Akt/mTOR axis inactivation in human
hepatocellular carcinoma. Mol Cancer Ther. 16:2711–2723. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Chen LM, Song TJ, Xiao JH, Huang ZH, Li Y
and Lin TY: Tripchlorolide induces autophagy in lung cancer cells
by inhibiting the PI3K/AKT/mTOR pathway and improves cisplatin
sensitivity in A549/DDP cells. Oncotarget. 8:63911–63922.
2017.PubMed/NCBI
|
|
11
|
Jin C, Zhang S, Yuan J, Wang X, Jin N and
Huang J: Hypoxia mediates the decreased sensibility of human lung
adenocarcinoma cell H1299 to cisplatin through inducing autophagy.
Minerva Chir. 73:113–116. 2017.PubMed/NCBI
|
|
12
|
Ma Z, Chen C, Tang P, Zhang H, Yue J and
Yu Z: BNIP3 induces apoptosis and protective autophagy under
hypoxia in esophageal squamous cell carcinoma cell lines: BNIP3
regulates cell death. Dis Esophagus. 30:1–8. 2017.PubMed/NCBI
|
|
13
|
Zhou H, Zheng L, Lu K, Gao Y, Guo L, Xu W
and Wang X: Downregulation of cohesin loading factor nipped-B-like
protein (NIPBL) induces cell cycle arrest, apoptosis, and autophagy
of breast cancer cell lines. Med Sci Monit. 23:4817–4825. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Samaras P, Tusup M, Nguyen-Kim TDL,
Seifert B, Bachmann H, von Moos R, Knuth A and Pascolo S: Phase I
study of a chloroquine-gemcitabine combination in patients with
metastatic or unresectable pancreatic cancer. Cancer Chemother
Pharmacol. 80:1005–1012. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Zhu J, Zheng Y, Zhang H, Zhu J and Sun H:
Low concentration of chloroquine enhanced efficacy of cisplatin in
the treatment of human ovarian cancer dependent on autophagy. Am J
Transl Res. 9:4046–4058. 2017.PubMed/NCBI
|
|
16
|
Chen HI, Tsai HP, Chen YT, Tsao SC and
Chai CY: Autophagy and apoptosis play opposing roles in overall
survival of esophageal squamous cell carcinoma. Pathol Oncol Res.
22:699–705. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Cilek EE, Ozturk H and Gur Dedeoglu B:
Construction of miRNA-miRNA networks revealing the complexity of
miRNA-mediated mechanisms in trastuzumab treated breast cancer cell
lines. PLoS One. 12:e01855582017. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Shivapurkar N, Vietsch EE, Carney E,
Isaacs C and Wellstein A: Circulating microRNAs in patients with
hormone receptor-positive, metastatic breast cancer treated with
dovitinib. Clin Transl Med. 6:372017. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Hu X, Wang Y, Liang H, Fan Q, Zhu R, Cui
J, Zhang W, Zen K, Zhang CY, Hou D, et al: miR-23a/b promote tumor
growth and suppress apoptosis by targeting PDCD4 in gastric cancer.
Cell Death Dis. 8:e30592017. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Mei LL, Wang WJ, Qiu YT, Xie XF, Bai J and
Shi ZZ: miR-125b-5p functions as a tumor suppressor gene partially
by regulating HMGA2 in esophageal squamous cell carcinoma. PLoS
One. 12:e01856362017. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Mei LL, Wang WJ, Qiu YT, Xie XF, Bai J and
Shi ZZ: miR-145-5p suppresses tumor cell migration, invasion and
epithelial to mesenchymal transition by regulating the Sp1/NF-κB
signaling pathway in esophageal squamous cell carcinoma. Int J Mol
Sci. 18:E18332017. View Article : Google Scholar
|
|
22
|
Ma T, Zhao Y, Lu Q, Lu Y, Liu Z, Xue T and
Shao Y: MicroRNA-30c functions as a tumor suppressor via targeting
SNAI1 in esophageal squamous cell carcinoma. Biomed Pharmacother.
98:680–686. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Sun Y, Li L, Xing S, Pan Y, Shi Y, Zhang L
and Shen Q: miR-503-3p induces apoptosis of lung cancer cells by
regulating p21 and CDK4 expression. Cancer Biomark. 20:597–608.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Xu K, Chen G, Qiu Y, Yuan Z, Li H, Yuan X,
Sun J, Xu J, Liang X and Yin P: miR-503-5p confers drug resistance
by targeting PUMA in colorectal carcinoma. Oncotarget.
8:21719–21732. 2017.PubMed/NCBI
|
|
25
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−ΔΔC(T)) method. Methods. 25:402–408. 2001. View Article : Google Scholar
|
|
26
|
Qiu T, Zhou L, Wang T, Xu J, Wang J, Chen
W, Zhou X, Huang Z, Zhu W, Shu Y, et al: miR-503 regulates the
resistance of non-small cell lung cancer cells to cisplatin by
targeting Bcl-2. Int J Mol Med. 32:593–598. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Hou S, Tian T, Qi D, Sun K, Yuan Q, Wang
Z, Qin Z, Wu Z, Chen Z and Zhang J: S100A4 promotes lung tumor
development through β-catenin pathway-mediated autophagy
inhibition. Cell Death Dis. 9:2772018. View Article : Google Scholar
|
|
28
|
Endo S, Hoshi M, Matsunaga T, Inoue T,
Ichihara K and Ikari A: Autophagy inhibition enhances anticancer
efficacy of artepillin C, a cinnamic acid derivative in Brazilian
green propolis. Biochem Biophys Res Commun. Feb 13–2018.Epub ahead
of print. View Article : Google Scholar
|
|
29
|
Kastenhuber ER, Lalazar G, Houlihan SL,
Tschaharganeh DF, Baslan T, Chen CC, Requena D, Tian S, Bosbach B,
Wilkinson JE, et al: DNAJB1-PRKACA fusion kinase interacts with
β-catenin and the liver regenerative response to drive
fibrolamellar hepato-cellular carcinoma. Proc Natl Acad Sci USA.
114:13076–13084. 2017. View Article : Google Scholar
|
|
30
|
Berthon AS, Szarek E and Stratakis CA:
PRKACA: The catalytic subunit of protein kinase A and
adrenocortical tumors. Front Cell Dev Biol. 3:262015. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Wu D, Cao G, Huang Z, Jin K, Hu H, Yu J
and Zeng Y: Decreased miR-503 expression in gastric cancer is
inversely correlated with serum carcinoembryonic antigen and acts
as a potential prognostic and diagnostic biomarker. Onco Targets
Ther. 10:129–135. 2016. View Article : Google Scholar
|
|
32
|
Yang X, Zang J, Pan X, Yin J, Xiang Q, Yu
J, Gan R and Lei X: miR-503 inhibits proliferation making human
hepatocellular carcinoma cells susceptible to 5 fluorouracil by
targeting EIF4E. Oncol Rep. 37:563–570. 2017. View Article : Google Scholar
|
|
33
|
Lu YC, Chen YJ, Wang HM, Tsai CY, Chen WH,
Huang YC, Fan KH, Tsai CN, Huang SF, Kang CJ, et al: Oncogenic
function and early detection potential of miRNA-10b in oral cancer
as identified by microRNA profiling. Cancer Prev Res (Phila).
5:665–674. 2012. View Article : Google Scholar
|
|
34
|
Yang Y, Liu L, Zhang Y, Guan H, Wu J, Zhu
X, Yuan J and Li M: MiR-503 targets I3K-85 and IKK-β and suppresses
progression of non-small cell lung cancer. Int J Cancer.
135:1531–1542. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Xu YY, Wu HJ, Ma HD, Xu LP, Huo Y and Yin
LR: MicroRNA-503 suppresses proliferation and cell-cycle
progression of endometrioid endometrial cancer by negatively
regulating cyclin D1. FEBS J. 280:3768–3779. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Tömböl Z, Szabó PM, Molnár V, Wiener Z,
Tölgyesi G, Horányi J, Riesz P, Reismann P, Patócs A, Likó I, et
al: Integrative molecular bioinformatics study of human
adrenocortical tumors: microRNA, tissue-specific target prediction,
and pathway analysis. Endocr Relat Cancer. 16:895–906. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Corbetta S, Vaira V, Guarnieri V,
Scillitani A, Eller-Vainicher C, Ferrero S, Vicentini L, Chiodini
I, Bisceglia M, Beck-Peccoz P, et al: Differential expression of
microRNAs in human parathyroid carcinomas compared with normal
parathyroid tissue. Endocr Relat Cancer. 17:135–146. 2010.
View Article : Google Scholar
|
|
38
|
Zhao JJ, Yang J, Lin J, Yao N, Zhu Y,
Zheng J, Xu J, Cheng JQ, Lin JY and Ma X: Identification of miRNAs
associated with tumorigenesis of retinoblastoma by miRNA microarray
analysis. Childs Nerv Syst. 25:13–20. 2009. View Article : Google Scholar
|
|
39
|
Chong Y, Zhang J, Guo X, Li G, Zhang S, Li
C, Jiao Z and Shao M: MicroRNA-503 acts as a tumor suppressor in
osteo-sarcoma by targeting L1CAM. PLoS One. 9:e1145852014.
View Article : Google Scholar
|
|
40
|
Peng Y, Liu YM, Li LC, Wang LL and Wu XL:
microRNA-503 inhibits gastric cancer cell growth and
epithelial-to-mesenchymal transition. Oncol Lett. 7:1233–1238.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Furukawa Y, Takasu A and Yura Y: Role of
autophagy in oncolytic herpes simplex virus type 1-induced cell
death in squamous cell carcinoma cells. Cancer Gene Ther.
24:393–400. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Wang T, Ge G, Ding Y, Zhou X, Huang Z, Zhu
W, Shu Y and Liu P: MiR-503 regulates cisplatin resistance of human
gastric cancer cell lines by targeting IGF1R and BCL2. Chin Med J
(Engl). 127:2357–2362. 2014.
|
|
43
|
Beristain AG, Molyneux SD, Joshi PA,
Pomroy NC, Di Grappa MA, Chang MC, Kirschner LS, Privé GG, Pujana
MA and Khokha R: PKA signaling drives mammary tumorigenesis through
Src. Oncogene. 34:1160–1173. 2015. View Article : Google Scholar
|
|
44
|
Moody SE, Schinzel AC, Singh S, Izzo F,
Strickland MR, Luo L, Thomas SR, Boehm JS, Kim SY, Wang ZC, et al:
PRKACA mediates resistance to HER2-targeted therapy in breast
cancer cells and restores anti-apoptotic signaling. Oncogene.
34:2061–2071. 2015. View Article : Google Scholar
|
|
45
|
Angelousi A, Szarek E, Shram V, Kebebew E,
Quezado M and Stratakis CA: Lipofuscin Accumulation in
Cortisol-Producing Adenomas With and Without PRKACA Mutations. Horm
Metab Res. 49:786–792. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Zhang B, Guo F, Ma Y, Song Y, Lin R, Shen
FY, Jin GZ, Li Y and Liu ZQ: Activation of D1R/PKA/mTOR signaling
cascade in medial prefrontal cortex underlying the antidepressant
effects of l-SPD. Sci Rep. 7:38092017. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
de Joussineau C, Sahut-Barnola I, Tissier
F, Dumontet T, Drelon C, Batisse-Lignier M, Tauveron I, Pointud JC,
Lefrançois-Martinez AM, Stratakis CA, et al: mTOR pathway is
activated by PKA in adrenocortical cells and participates in vivo
to apoptosis resistance in primary pigmented nodular adrenocortical
disease (PPNAD). Hum Mol Genet. 23:5418–5428. 2014. View Article : Google Scholar :
|
|
48
|
Hu J, Cui W, Ding W, Gu Y, Wang Z and Fan
W: Globular adipo-nectin attenuated H O inducing autophagy through
the AMPK/mTOR pathway. Cell 2 2-induced apoptosis in rat
chondrocytes by Physiol Biochem. 43:367–382. 2017.
|
|
49
|
Lan SH, Wu SY, Zuchini R, Lin XZ, Su IJ,
Tsai TF, Lin YJ, Wu CT and Liu HS: Autophagy-preferential
degradation of MIR224 participates in hepatocellular carcinoma
tumorigenesis. Autophagy. 10:1687–1689. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Grassi G, Di Caprio G, Santangelo L, Fimia
GM, Cozzolino AM, Komatsu M, Ippolito G, Tripodi M and Alonzi T:
Autophagy regulates hepatocyte identity and
epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions
promoting Snail degradation. Cell Death Dis. 6:e18802015.
View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Catalano M, D'Alessandro G, Lepore F,
Corazzari M, Caldarola S, Valacca C, Faienza F, Esposito V,
Limatola C, Cecconi F, et al: Autophagy induction impairs migration
and invasion by reversing EMT in glioblastoma cells. Mol Oncol.
9:1612–1625. 2015. View Article : Google Scholar : PubMed/NCBI
|
