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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2018 Volume 52 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Functions of chemokines in the perineural invasion of tumors (Review)

Mei Zhang, Zhuo-Li Zhu, Xiao-Lei Gao, Jia-Shun Wu, Xin-Hua Liang, Ya-Ling Tang
Pages: 1369-1379
Published online on: 08 March 2018

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Article Open Access

A novel polysaccharide derived from algae extract inhibits cancer progression via JNK, not via the p38 MAPK signaling pathway

Peiyu Xie, Fukuko Horio, Isao Fujii, Jien Zhao, Makoto Shinohara, Makoto Matsukura
Pages: 1380-1390
Published online on: 02 March 2018

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Article Open Access

A novel therapeutic strategy of personalized medicine based on anti-epidermal growth factor receptor monoclonal antibodies in patients with metastatic colorectal cancer

Nobuhisa Matsuhashi, Takao Takahashi, Satoshi Matsui, Toshiyuki Tanahashi, Hisashi Imai, Yoshihiro Tanaka, Kazuya Yamaguchi, Kazuhiro Yoshida
Pages: 1391-1400
Published online on: 16 March 2018

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Article Open Access

Polo-like kinase 2 promotes chemoresistance and predicts limited survival benefit from adjuvant chemotherapy in colorectal cancer

Yuquan Xie, Ying Liu, Qiubo Li, Jianming Chen
Pages: 1401-1414
Published online on: 20 March 2018

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Article Open Access

Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells

Zhanhui Du, Xiuxiang Song, Fangfang Yan, Jingjing Wang, Yuxia Zhao, Shangming Liu
Pages: 1415-1426
Published online on: 16 March 2018

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Article Open Access

miR-503 suppresses the proliferation and metastasis of esophageal squamous cell carcinoma by triggering autophagy via PKA/mTOR signaling

Jian Wu, Fengxia Gao, Tao Xu, Xin Deng, Chao Wang, Xiaoyan Yang, Zhi Hu, Yang Long, Xuemei He, Guannan Liang, Delian Ren, Tianyang Dai
Pages: 1427-1442
Published online on: 16 March 2018

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Article Open Access

EPB41L3 is a potential tumor suppressor gene and prognostic indicator in esophageal squamous cell carcinoma

Rong Zeng, Yi Liu, Zhao-Jing Jiang, Jun-Peng Huang, Yu Wang, Xu-Feng Li, Wei-Bin Xiong, Xiao-Cong Wu, Ji-Ren Zhang, Qi-En Wang, Yan-Fang Zheng
Pages: 1443-1454
Published online on: 14 March 2018

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Article Open Access

FSCN‑1 increases doxorubicin resistance in hepatocellular carcinoma through promotion of epithelial-mesenchymal transition

Yuanbiao Zhang, Yi Lu, Chengwu Zhang, Dongsheng Huang, Weiding Wu, Yuhua Zhang, Jian Shen, Ying Cai, Wei Chen, Weifeng Yao
Pages: 1455-1464
Published online on: 20 March 2018

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Article Open Access

Disruption of IGF‑1R signaling by a novel quinazoline derivative, HMJ‑30, inhibits invasiveness and reverses epithelial-mesenchymal transition in osteosarcoma U‑2 OS cells

Yu-Jen Chiu, Mann-Jen Hour, Yi-An Jin, Chi-Cheng Lu, Fuu-Jen Tsai, Tai-Lin Chen, Hsu Ma, Yu-Ning Juan, Jai-Sing Yang
Pages: 1465-1478
Published online on: 16 March 2018

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Article Open Access

Studying the mechanism of PLAGL2 overexpression and its carcinogenic characteristics based on 3'-untranslated region in colorectal cancer

Chen Su, Daojiang Li, Nanpeng Li, Yuheng Du, Chunxing Yang, Yang Bai, Changwei Lin, Xiaorong Li, Yi Zhang
Pages: 1479-1490
Published online on: 06 March 2018

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Article Open Access

Downregulation of miR-374b-5p promotes chemotherapeutic resistance in pancreatic cancer by upregulating multiple anti-apoptotic proteins

Di Sun, Xu Wang, Guoqing Sui, Si Chen, Miao Yu, Ping Zhang
Pages: 1491-1503
Published online on: 14 March 2018

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Article Open Access

Pterostilbene modulates the suppression of multidrug resistance protein 1 and triggers autophagic and apoptotic mechanisms in cisplatin-resistant human oral cancer CAR cells via AKT signaling

Hui-Ping Chang, Chi-Cheng Lu, Jo-Hua Chiang, Fuu-Jen Tsai, Yu-Ning Juan, Je-Wei Tsao, Hong-Yi Chiu, Jai-Sing Yang
Pages: 1504-1514
Published online on: 02 March 2018

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Article Open Access

Downregulation of SIRT6 by miR-34c-5p is associated with poor prognosis and promotes colon cancer proliferation through inhibiting apoptosis via the JAK2/STAT3 signaling pathway

Ning Li, Dong Mao, Yansha Cao, Hua Li, Fu Ren, Keyan Li
Pages: 1515-1527
Published online on: 05 March 2018

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Article Open Access

Increased interleukin-17A levels promote rituximab resistance by suppressing p53 expression and predict an unfavorable prognosis in patients with diffuse large B cell lymphoma

Weijie Zhong, Xin Xu, Zhigang Zhu, Li Yang, Hong Du, Zhongjun Xia, Zhaohu Yuan, Huabao Xiong, Qinghua Du, Yaming Wei, Qingshan Li
Pages: 1528-1538
Published online on: 05 March 2018

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Article

Frequent downregulation of LRRC26 by epigenetic alterations is involved in the malignant progression of triple-negative breast cancer

Yoshimasa Miyagawa, Yosuke Matsushita, Hiromu Suzuki, Masato Komatsu, Tetsuro Yoshimaru, Ryuichiro Kimura, Ayako Yanai, Junko Honda, Akira Tangoku, Mitsunori Sasa, Yasuo Miyoshi, Toyomasa Katagiri
Pages: 1539-1558
Published online on: 05 March 2018

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Article

FLVCR1 promotes the proliferation and tumorigenicity of synovial sarcoma through inhibiting apoptosis and autophagy

Changliang Peng, Yan Song, Wei Chen, Xiaoying Wang, Xiaoli Liu, Fang Wang, Dongjin Wu, Shengzhong Ma, Xiuwen Wang, Chunzheng Gao
Pages: 1559-1568
Published online on: 08 March 2018

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Article

Ethoxysanguinarine inhibits viability and induces apoptosis of colorectal cancer cells by inhibiting CIP2A

Lan Jin, Yuan Si, Xing Hong, Pengfei Liu, Beibei Zhu, Huiliang Yu, Xinhua Zhao, Shanshan Qin, Mengyuan Xiong, Ying Liu, Zhiguo Luo, Yang Guo
Pages: 1569-1578
Published online on: 16 March 2018

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Article

IL‑17 induces NSCLC A549 cell proliferation via the upregulation of HMGA1, resulting in an increased cyclin D1 expression

Chenhui Zhao, Yongting Li, Weiming Zhang, Dan Zhao, Ling Ma, Pei Ma, Fengming Yang, Yingwei Wang, Yongqian Shu, Wen Qiu
Pages: 1579-1592
Published online on: 07 March 2018

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Article

Curcumin inhibits superoxide dismutase-induced epithelial-to-mesenchymal transition via the PI3K/Akt/NF-κB pathway in pancreatic cancer cells

Wei Li, Zhengdong Jiang, Xue Xiao, Zheng Wang, Zheng Wu, Qingyong Ma, Lei Cao
Pages: 1593-1602
Published online on: 01 March 2018

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Article

Long non-coding RNA KCNQ1OT1 mediates the growth of hepatocellular carcinoma by functioning as a competing endogenous RNA of miR-504 Corrigendum in /10.3892/ijo.2020.4971

Chao Li, Runchen Miao, Jingyao Zhang, Kai Qu, Chang Liu
Pages: 1603-1612
Published online on: 12 March 2018

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Article

PTBP1 knockdown in renal cell carcinoma inhibits cell migration, invasion and angiogenesis in vitro and metastasis in vivo via the hypoxia inducible factor-1α pathway

Haixia Shan, Pingfu Hou, Meng Zhang, Liantao Li, Yu Pan, Fang Chen, Tao Jiang, Jin Bai, Junnian Zheng
Pages: 1613-1622
Published online on: 02 March 2018

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Article

Interferon regulatory factor 3 mediates Poly(I:C)-induced innate immune response and apoptosis in non‑small cell lung cancer

Liang Yi, Dan Sun, Qian Han, Zhonghui Liu, Zeng Zeng, Yanping Wu, Xiaoyu Chai, Xinmin Liu
Pages: 1623-1632
Published online on: 05 March 2018

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Article

Programmed cell death 4 overexpression enhances sensitivity to cisplatin via the JNK/c-Jun signaling pathway in bladder cancer

Junli Liu, Ruirui Zhai, Jingjie Zhao, Feng Kong, Jue Wang, Wen Jiang, Qian Xin, Xia Xue, Yun Luan
Pages: 1633-1642
Published online on: 05 March 2018

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Article

Silencing of aquaporin 5 inhibits the growth of A549 lung cancer cells in vitro and in vivo

Lin Zhang, Jia Lu, Hongyan Zhou, Zhenwu Du, Guizhen Zhang
Pages: 1643-1650
Published online on: 16 March 2018

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Article

Asparaginyl endopeptidase enhances pancreatic ductal adenocarcinoma cell invasion in an exosome-dependent manner and correlates with poor prognosis

Qiang Yan, Wen-Bin Yuan, Xu Sun, Ming-Jie Zhang, Feng Cen, Shi-Yu Zhou, Wan-Bo Wu, Yong‑Can Xu, Li-Hui Tong, Zhi-Hong Ma
Pages: 1651-1660
Published online on: 15 March 2018

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Article

Apigenin induces apoptosis by suppressing Bcl-xl and Mcl-1 simultaneously via signal transducer and activator of transcription 3 signaling in colon cancer

Yuzo Maeda, Hiroki Takahashi, Nozomu Nakai, Takeshi Yanagita, Nanako Ando, Tomotaka Okubo, Kenta Saito, Kazuyoshi Shiga, Takahisa Hirokawa, Masayasu Hara, Hideyuki Ishiguro, Yoichi Matsuo, Shuji Takiguchi
Pages: 1661-1673
Published online on: 07 March 2018

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Article

BCSC-1 suppresses human breast cancer metastasis by inhibiting NF-κB signaling

Dalin Di, Lei Chen, Yingying Guo, Lina Wang, Chunling Zhao, Jiyu Ju
Pages: 1674-1684
Published online on: 07 March 2018

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Article

Overexpression of satellite alpha transcripts leads to chromosomal instability via segregation errors at specific chromosomes

Kosuke Ichida, Koichi Suzuki, Taro Fukui, Yuji Takayama, Nao Kakizawa, Fumiaki Watanabe, Hideki Ishikawa, Yuta Muto, Takaharu Kato, Masaaki Saito, Kazushige Futsuhara, Yasuyuki Miyakura, Hiroshi Noda, Tsukasa Ohmori, Fumio Konishi, Toshiki Rikiyama
Pages: 1685-1693
Published online on: 16 March 2018

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Article

Overexpression of collagen type V α1 chain in human breast invasive ductal carcinoma is mediated by TGF-β1

Weimin Ren, Youyuan Zhang, Lingyun Zhang, Qunbo Lin, Jinguo Zhang, Guoxiong Xu
Pages: 1694-1704
Published online on: 15 March 2018

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Article

Ubiquitin-specific peptidase 5 and ovarian tumor deubiquitinase 6A are differentially expressed in p53+/+ and p53-/- HCT116 cells

Soo-Yeon Kim, Seul-Ki Kwon, So-Young Lee, Kwang-Hyun Baek
Pages: 1705-1714
Published online on: 05 March 2018

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Article

Anthocyanin complex exerts anti-cholangiocarcinoma activities and improves the efficacy of drug treatment in a gemcitabine-resistant cell line

Kitti Intuyod, Aroonsri Priprem, Chawalit Pairojkul, Chariya Hahnvajanawong, Kulthida Vaeteewoottacharn, Porntip Pinlaor, Somchai Pinlaor
Pages: 1715-1726
Published online on: 07 March 2018

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Article

Ciprofloxacin triggers the apoptosis of human triple-negative breast cancer MDA-MB-231 cells via the p53/Bax/Bcl-2 signaling pathway

Artur Beberok, Dorota Wrześniok, Jakub Rok, Zuzanna Rzepka, Michalina Respondek, Ewa Buszman
Pages: 1727-1737
Published online on: 08 March 2018

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Article

Lemongrass essential oil and citral inhibit Src/Stat3 activity and suppress the proliferation/survival of small-cell lung cancer cells, alone or in combination with chemotherapeutic agents

Takayuki Maruoka, Akira Kitanaka, Yoshitsugu Kubota, Genji Yamaoka, Tomohiro Kameda, Osamu Imataki, Hiroaki Dobashi, Shuji Bandoh, Norimitsu Kadowaki, Terukazu Tanaka
Pages: 1738-1748
Published online on: 13 March 2018

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Article

Oridonin induces apoptosis in oral squamous cell carcinoma probably through the generation of reactive oxygen species and the p38/JNK MAPK pathway

Ha-Na Oh, Ji-Hye Seo, Mee-Hyun Lee, Goo Yoon, Seung-Sik Cho, Kangdong Liu, Hyunji Choi, Keon Bong Oh, Young-Sik Cho, Hangun Kim, A Lum Han, Jung-Il Chae, Jung-Hyun Shim
Pages: 1749-1759
Published online on: 16 March 2018

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Targeted therapies for urothelial carcinoma: From FGFR inhibitors to next‑generation antibody-drug conjugates (Review)

Jinping Du, Hao Shen, Tongwei Zeng, Wei Liu, Yongqiang Xie
Article Number: 28
Published online on: 22 December 2025

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Expression of Concern Open Access

[Expression of Concern] Establishment and evaluation of a new highly metastatic tumor cell line 5a‑D‑Luc‑ZsGreen expressing both luciferase and green fluorescent protein

Hitomi Sudo, Atsushi B. Tsuji, Aya Sugyo, Hiroyuki Takuwa, Kazuto Masamoto, Yutaka Tomita, Norihiro Suzuki, Takeshi Imamura, Mitsuru Koizumi, Tsuneo Saga
Article Number: 27
Published online on: 17 December 2025

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Review Open Access

Exosomal circRNAs in hepatocellular carcinoma: Implications for the development and therapeutic resistance of hepatocellular carcinoma (Review)

Zhiyao Liu, Yuqiao Wang, Yali Wang, Yucheng Zhang
Article Number: 26
Published online on: 16 December 2025

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Review Open Access

Advancements on the synergistic application of oncolytic viruses and molecularly targeted therapies for the treatment of solid tumors (Review)

Shiwen Bi, Tiyan Shan, Yong Tang, Qi Wang
Article Number: 25
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] Epigenetic high regulation of ATAD2 regulates the Hh pathway in human hepatocellular carcinoma

Gang Wu, Xiaojun Lu, Yawei Wang, Hui He, Xiangyu Meng, Shuguan Xia, Kunming Zhen, Yongfeng Liu
Article Number: 24
Published online on: 16 December 2025

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Review

CCDC137: A key hub for RNA and epigenetic regulation in cancer research (Review)

Xiaoying Zhao, Wenjing Zhang, Xiang Yu, Xiaohan Zhao, Xu Dai, Sirui Chen, Yan Wang, Jiang Cheng, Weiwei Zheng
Article Number: 23
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] Characterization of side population cells isolated from the colon cancer cell line SW480

Binghong Xiong, Li Ma, Xiang Hu, Caiquan Zhang, Yong Cheng
Article Number: 22
Published online on: 10 December 2025

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Review Open Access

mTOR in radiotherapy of lung cancer: Mechanisms of radiation resistance and therapeutic implications (Review)

Xiao Pang, Huai Liu, Ying Long, Hui Wang
Article Number: 21
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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Journal Cover
March-2026 Volume 68 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Suppression of the death gene BIK is a critical factor for resistance to tamoxifen in MCF‑7 breast cancer cells

Rubí Viedma-Rodriguez, Luis Arturo Baiza-Gutman, Alejandro García-Carrancá, Leticia Moreno-Fierros, Fabio Salamanca-Gómez, Diego Arenas-Aranda
Article Number: 29
Published online on: 23 December 2025

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