Journal Articles

Functions of chemokines in the perineural invasion of tumors (Review)

Mei Zhang, Zhuo-Li Zhu, Xiao-Lei Gao, Jia-Shun Wu, Xin-Hua Liang, Ya-Ling Tang

Pages: 1369-1379 Published online on: 08 March 2018
Open Access

A novel polysaccharide derived from algae extract inhibits cancer progression via JNK, not via the p38 MAPK signaling pathway

Peiyu Xie, Fukuko Horio, Isao Fujii, Jien Zhao, Makoto Shinohara, Makoto Matsukura

Pages: 1380-1390 Published online on: 02 March 2018
Open Access

A novel therapeutic strategy of personalized medicine based on anti-epidermal growth factor receptor monoclonal antibodies in patients with metastatic colorectal cancer

Nobuhisa Matsuhashi, Takao Takahashi, Satoshi Matsui, Toshiyuki Tanahashi, Hisashi Imai, Yoshihiro Tanaka, Kazuya Yamaguchi, Kazuhiro Yoshida

Pages: 1391-1400 Published online on: 16 March 2018
Open Access

Polo-like kinase 2 promotes chemoresistance and predicts limited survival benefit from adjuvant chemotherapy in colorectal cancer

Yuquan Xie, Ying Liu, Qiubo Li, Jianming Chen

Pages: 1401-1414 Published online on: 20 March 2018
Open Access

Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells

Zhanhui Du, Xiuxiang Song, Fangfang Yan, Jingjing Wang, Yuxia Zhao, Shangming Liu

Pages: 1415-1426 Published online on: 16 March 2018
Open Access

miR-503 suppresses the proliferation and metastasis of esophageal squamous cell carcinoma by triggering autophagy via PKA/mTOR signaling

Jian Wu, Fengxia Gao, Tao Xu, Xin Deng, Chao Wang, Xiaoyan Yang, Zhi Hu, Yang Long, Xuemei He, Guannan Liang, Delian Ren, Tianyang Dai

Pages: 1427-1442 Published online on: 16 March 2018
Open Access

EPB41L3 is a potential tumor suppressor gene and prognostic indicator in esophageal squamous cell carcinoma

Rong Zeng, Yi Liu, Zhao-Jing Jiang, Jun-Peng Huang, Yu Wang, Xu-Feng Li, Wei-Bin Xiong, Xiao-Cong Wu, Ji-Ren Zhang, Qi-En Wang, Yan-Fang Zheng

Pages: 1443-1454 Published online on: 14 March 2018
Open Access

FSCN‑1 increases doxorubicin resistance in hepatocellular carcinoma through promotion of epithelial-mesenchymal transition

Yuanbiao Zhang, Yi Lu, Chengwu Zhang, Dongsheng Huang, Weiding Wu, Yuhua Zhang, Jian Shen, Ying Cai, Wei Chen, Weifeng Yao

Pages: 1455-1464 Published online on: 20 March 2018
Open Access

Disruption of IGF‑1R signaling by a novel quinazoline derivative, HMJ‑30, inhibits invasiveness and reverses epithelial-mesenchymal transition in osteosarcoma U‑2 OS cells

Yu-Jen Chiu, Mann-Jen Hour, Yi-An Jin, Chi-Cheng Lu, Fuu-Jen Tsai, Tai-Lin Chen, Hsu Ma, Yu-Ning Juan, Jai-Sing Yang

Pages: 1465-1478 Published online on: 16 March 2018
Open Access

Studying the mechanism of PLAGL2 overexpression and its carcinogenic characteristics based on 3'-untranslated region in colorectal cancer

Chen Su, Daojiang Li, Nanpeng Li, Yuheng Du, Chunxing Yang, Yang Bai, Changwei Lin, Xiaorong Li, Yi Zhang

Pages: 1479-1490 Published online on: 06 March 2018
Open Access

Downregulation of miR-374b-5p promotes chemotherapeutic resistance in pancreatic cancer by upregulating multiple anti-apoptotic proteins

Di Sun, Xu Wang, Guoqing Sui, Si Chen, Miao Yu, Ping Zhang

Pages: 1491-1503 Published online on: 14 March 2018
Open Access

Pterostilbene modulates the suppression of multidrug resistance protein 1 and triggers autophagic and apoptotic mechanisms in cisplatin-resistant human oral cancer CAR cells via AKT signaling

Hui-Ping Chang, Chi-Cheng Lu, Jo-Hua Chiang, Fuu-Jen Tsai, Yu-Ning Juan, Je-Wei Tsao, Hong-Yi Chiu, Jai-Sing Yang

Pages: 1504-1514 Published online on: 02 March 2018
Open Access

Increased interleukin-17A levels promote rituximab resistance by suppressing p53 expression and predict an unfavorable prognosis in patients with diffuse large B cell lymphoma

Weijie Zhong, Xin Xu, Zhigang Zhu, Li Yang, Hong Du, Zhongjun Xia, Zhaohu Yuan, Huabao Xiong, Qinghua Du, Yaming Wei, Qingshan Li

Pages: 1528-1538 Published online on: 05 March 2018

Frequent downregulation of LRRC26 by epigenetic alterations is involved in the malignant progression of triple-negative breast cancer

Yoshimasa Miyagawa, Yosuke Matsushita, Hiromu Suzuki, Masato Komatsu, Tetsuro Yoshimaru, Ryuichiro Kimura, Ayako Yanai, Junko Honda, Akira Tangoku, Mitsunori Sasa, Yasuo Miyoshi, Toyomasa Katagiri

Pages: 1539-1558 Published online on: 05 March 2018

FLVCR1 promotes the proliferation and tumorigenicity of synovial sarcoma through inhibiting apoptosis and autophagy

Changliang Peng, Yan Song, Wei Chen, Xiaoying Wang, Xiaoli Liu, Fang Wang, Dongjin Wu, Shengzhong Ma, Xiuwen Wang, Chunzheng Gao

Pages: 1559-1568 Published online on: 08 March 2018

Ethoxysanguinarine inhibits viability and induces apoptosis of colorectal cancer cells by inhibiting CIP2A

Lan Jin, Yuan Si, Xing Hong, Pengfei Liu, Beibei Zhu, Huiliang Yu, Xinhua Zhao, Shanshan Qin, Mengyuan Xiong, Ying Liu, Zhiguo Luo, Yang Guo

Pages: 1569-1578 Published online on: 16 March 2018

IL‑17 induces NSCLC A549 cell proliferation via the upregulation of HMGA1, resulting in an increased cyclin D1 expression

Chenhui Zhao, Yongting Li, Weiming Zhang, Dan Zhao, Ling Ma, Pei Ma, Fengming Yang, Yingwei Wang, Yongqian Shu, Wen Qiu

Pages: 1579-1592 Published online on: 07 March 2018

Curcumin inhibits superoxide dismutase-induced epithelial-to-mesenchymal transition via the PI3K/Akt/NF-κB pathway in pancreatic cancer cells

Wei Li, Zhengdong Jiang, Xue Xiao, Zheng Wang, Zheng Wu, Qingyong Ma, Lei Cao

Pages: 1593-1602 Published online on: 01 March 2018

Long non-coding RNA KCNQ1OT1 mediates the growth of hepatocellular carcinoma by functioning as a competing endogenous RNA of miR-504

Chao Li, Runchen Miao, Jingyao Zhang, Kai Qu, Chang Liu

Pages: 1603-1612 Published online on: 12 March 2018

PTBP1 knockdown in renal cell carcinoma inhibits cell migration, invasion and angiogenesis in vitro and metastasis in vivo via the hypoxia inducible factor-1α pathway

Haixia Shan, Pingfu Hou, Meng Zhang, Liantao Li, Yu Pan, Fang Chen, Tao Jiang, Jin Bai, Junnian Zheng

Pages: 1613-1622 Published online on: 02 March 2018

Interferon regulatory factor 3 mediates Poly(I:C)-induced innate immune response and apoptosis in non‑small cell lung cancer

Liang Yi, Dan Sun, Qian Han, Zhonghui Liu, Zeng Zeng, Yanping Wu, Xiaoyu Chai, Xinmin Liu

Pages: 1623-1632 Published online on: 05 March 2018

Programmed cell death 4 overexpression enhances sensitivity to cisplatin via the JNK/c-Jun signaling pathway in bladder cancer

Junli Liu, Ruirui Zhai, Jingjie Zhao, Feng Kong, Jue Wang, Wen Jiang, Qian Xin, Xia Xue, Yun Luan

Pages: 1633-1642 Published online on: 05 March 2018

Silencing of aquaporin 5 inhibits the growth of A549 lung cancer cells in vitro and in vivo

Lin Zhang, Jia Lu, Hongyan Zhou, Zhenwu Du, Guizhen Zhang

Pages: 1643-1650 Published online on: 16 March 2018

Asparaginyl endopeptidase enhances pancreatic ductal adenocarcinoma cell invasion in an exosome-dependent manner and correlates with poor prognosis

Qiang Yan, Wen-Bin Yuan, Xu Sun, Ming-Jie Zhang, Feng Cen, Shi-Yu Zhou, Wan-Bo Wu, Yong‑Can Xu, Li-Hui Tong, Zhi-Hong Ma

Pages: 1651-1660 Published online on: 15 March 2018

Apigenin induces apoptosis by suppressing Bcl-xl and Mcl-1 simultaneously via signal transducer and activator of transcription 3 signaling in colon cancer

Yuzo Maeda, Hiroki Takahashi, Nozomu Nakai, Takeshi Yanagita, Nanako Ando, Tomotaka Okubo, Kenta Saito, Kazuyoshi Shiga, Takahisa Hirokawa, Masayasu Hara, Hideyuki Ishiguro, Yoichi Matsuo, Shuji Takiguchi

Pages: 1661-1673 Published online on: 07 March 2018

BCSC-1 suppresses human breast cancer metastasis by inhibiting NF-κB signaling

Dalin Di, Lei Chen, Yingying Guo, Lina Wang, Chunling Zhao, Jiyu Ju

Pages: 1674-1684 Published online on: 07 March 2018

Overexpression of satellite alpha transcripts leads to chromosomal instability via segregation errors at specific chromosomes

Kosuke Ichida, Koichi Suzuki, Taro Fukui, Yuji Takayama, Nao Kakizawa, Fumiaki Watanabe, Hideki Ishikawa, Yuta Muto, Takaharu Kato, Masaaki Saito, Kazushige Futsuhara, Yasuyuki Miyakura, Hiroshi Noda, Tsukasa Ohmori, Fumio Konishi, Toshiki Rikiyama

Pages: 1685-1693 Published online on: 16 March 2018

Overexpression of collagen type V α1 chain in human breast invasive ductal carcinoma is mediated by TGF-β1

Weimin Ren, Youyuan Zhang, Lingyun Zhang, Qunbo Lin, Jinguo Zhang, Guoxiong Xu

Pages: 1694-1704 Published online on: 15 March 2018

Ubiquitin-specific peptidase 5 and ovarian tumor deubiquitinase 6A are differentially expressed in p53+/+ and p53-/- HCT116 cells

Soo-Yeon Kim, Seul-Ki Kwon, So-Young Lee, Kwang-Hyun Baek

Pages: 1705-1714 Published online on: 05 March 2018

Anthocyanin complex exerts anti-cholangiocarcinoma activities and improves the efficacy of drug treatment in a gemcitabine-resistant cell line

Kitti Intuyod, Aroonsri Priprem, Chawalit Pairojkul, Chariya Hahnvajanawong, Kulthida Vaeteewoottacharn, Porntip Pinlaor, Somchai Pinlaor

Pages: 1715-1726 Published online on: 07 March 2018

Ciprofloxacin triggers the apoptosis of human triple-negative breast cancer MDA-MB-231 cells via the p53/Bax/Bcl-2 signaling pathway

Artur Beberok, Dorota Wrześniok, Jakub Rok, Zuzanna Rzepka, Michalina Respondek, Ewa Buszman

Pages: 1727-1737 Published online on: 08 March 2018

Lemongrass essential oil and citral inhibit Src/Stat3 activity and suppress the proliferation/survival of small-cell lung cancer cells, alone or in combination with chemotherapeutic agents

Takayuki Maruoka, Akira Kitanaka, Yoshitsugu Kubota, Genji Yamaoka, Tomohiro Kameda, Osamu Imataki, Hiroaki Dobashi, Shuji Bandoh, Norimitsu Kadowaki, Terukazu Tanaka

Pages: 1738-1748 Published online on: 13 March 2018

Oridonin induces apoptosis in oral squamous cell carcinoma probably through the generation of reactive oxygen species and the p38/JNK MAPK pathway

Ha-Na Oh, Ji-Hye Seo, Mee-Hyun Lee, Goo Yoon, Seung-Sik Cho, Kangdong Liu, Hyunji Choi, Keon Bong Oh, Young-Sik Cho, Hangun Kim, A Lum Han, Jung-Il Chae, Jung-Hyun Shim

Pages: 1749-1759 Published online on: 16 March 2018
Journal Cover

Cover Legend PDF

May 2018
Volume 52 Issue 5

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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