|
1
|
Ferlay J, Shin HR, Bray F, Forman D,
Mathers C and Parkin DM: Estimates of worldwide burden of cancer in
2008: GLOBOCAN 2008. Int J Cancer. 127:2893–2917. 2010. View Article : Google Scholar
|
|
2
|
Jemal A, Siegel R, Ward E, Hao Y, Xu J and
Thun MJ: Cancer statistics, 2009. CA Cancer J Clin. 59:225–249.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Enzinger PC and Mayer RJ: Esophageal
cancer. N Engl J Med. 349:2241–2252. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Kamangar F, Dores GM and Anderson WF:
Patterns of cancer incidence, mortality, and prevalence across five
continents: Defining priorities to reduce cancer disparities in
different geographic regions of the world. J Clin Oncol.
24:2137–2150. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Eslick GD: Epidemiology of esophageal
cancer. Gastroenterol Clin North Am. 38:17–25. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Murrow L and Debnath J: Autophagy as a
stress-response and quality-control mechanism: Implications for
cell injury and human disease. Annu Rev Pathol. 8:105–137. 2013.
View Article : Google Scholar
|
|
7
|
Martinet W, De Meyer GR, Andries L, Herman
AG and Kockx MM: In situ detection of starvation-induced autophagy.
J Histochem Cytochem. 54:85–96. 2006. View Article : Google Scholar
|
|
8
|
Yang Y, Yang Y, Yang X, Zhu H, Guo Q, Chen
X, Zhang H, Cheng H and Sun X: Autophagy and its function in
radiosensitivity. Tumour Biol. 36:4079–4087. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Chen X, Wang P, Guo F, Wang X, Wang J, Xu
J, Yuan D, Zhang J and Shao C: Autophagy enhanced the
radioresistance of non-small cell lung cancer by regulating ROS
level under hypoxia condition. Int J Radiat Biol. 93:764–770. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Lomonaco SL, Finniss S, Xiang C,
Decarvalho A, Umansky F, Kalkanis SN, Mikkelsen T and Brodie C: The
induction of autophagy by gamma-radiation contributes to the
radioresistance of glioma stem cells. Int J Cancer. 125:717–722.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Chaachouay H, Ohneseit P, Toulany M,
Kehlbach R, Multhoff G and Rodemann HP: Autophagy contributes to
resistance of tumor cells to ionizing radiation. Radiother Oncol.
99:287–292. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Chen Y, Li X, Guo L, Wu X, He C, Zhang S,
Xiao Y, Yang Y and Hao D: Combining radiation with autophagy
inhibition enhances suppression of tumor growth and angiogenesis in
esophageal cancer. Mol Med Rep. 12:1645–1652. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Liang DH, El-Zein R and Dave B: Autophagy
inhibition to increase radiosensitization in breast cancer. J Nucl
Med Radiat Ther. 6:62015. View Article : Google Scholar
|
|
14
|
Lopez J and Tait SW: Mitochondrial
apoptosis: Killing cancer using the enemy within. Br J Cancer.
112:957–962. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Tait SW and Green DR: Mitochondria and
cell death: Outer membrane permeabilization and beyond. Nat Rev Mol
Cell Biol. 11:621–632. 2010. View
Article : Google Scholar : PubMed/NCBI
|
|
16
|
Chen Z, Wang B, Yu F, Chen Q, Tian Y, Ma S
and Liu X: The roles of mitochondria in radiation-induced
autophagic cell death in cervical cancer cells. Tumour Biol.
37:4083–4091. 2016. View Article : Google Scholar
|
|
17
|
Bristol ML, Di X, Beckman MJ, Wilson EN,
Henderson SC, Maiti A, Fan Z and Gewirtz DA: Dual functions of
autophagy in the response of breast tumor cells to radiation:
Cytoprotective autophagy with radiation alone and cytotoxic
autophagy in radiosensitization by vitamin D 3. Autophagy.
8:739–753. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Wilson EN, Bristol ML, Di X, Maltese WA,
Koterba K, Beckman MJ and Gewirtz DA: A switch between
cytoprotective and cytotoxic autophagy in the radiosensitization of
breast tumor cells by chloroquine and vitamin D. Horm Cancer.
2:272–285. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Apel A, Herr I, Schwarz H, Rodemann HP and
Mayer A: Blocked autophagy sensitizes resistant carcinoma cells to
radiation therapy. Cancer Res. 68:1485–1494. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Kondo Y, Kanzawa T, Sawaya R and Kondo S:
The role of autophagy in cancer development and response to
therapy. Nat Rev Cancer. 5:726–734. 2005. View Article : Google Scholar
|
|
21
|
Sotelo J, Briceño E and López-González MA:
Adding chloroquine to conventional treatment for glioblastoma
multiforme: A randomized, double-blind, placebo-controlled trial.
Ann Intern Med. 144:337–343. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
23
|
Feng Y, He D, Yao Z and Klionsky DJ: The
machinery of macroautophagy. Cell Res. 24:24–41. 2014. View Article : Google Scholar :
|
|
24
|
Mizushima N and Yoshimori T: How to
interpret LC3 immunoblotting. Autophagy. 3:542–545. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Kabeya Y, Mizushima N, Ueno T, Yamamoto A,
Kirisako T, Noda T, Kominami E, Ohsumi Y and Yoshimori T: LC3, a
mammalian homologue of yeast Apg8p, is localized in autophagosome
membranes after processing. EMBO J. 19:5720–5728. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Amaravadi RK, Lippincott-Schwartz J, Yin
XM, Weiss WA, Takebe N, Timmer W, DiPaola RS, Lotze MT and White E:
Principles and current strategies for targeting autophagy for
cancer treatment. Clin Cancer Res. 17:654–666. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Grandér D and Panaretakis T: Autophagy:
Cancer therapy's friend or foe? Future Med Chem. 2:285–297. 2010.
View Article : Google Scholar
|
|
28
|
He Y, Zhao X, Subahan NR, Fan L, Gao J and
Chen H: The prognostic value of autophagy-related markers beclin-1
and microtubule-associated protein light chain 3B in cancers: A
systematic review and meta-analysis. Tumour Biol. 35:7317–7326.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Clarke AR, Purdie CA, Harrison DJ, Morris
RG, Bird CC, Hooper ML and Wyllie AH: Thymocyte apoptosis induced
by p53-dependent and independent pathways. Nature. 362:849–852.
1993. View Article : Google Scholar
|
|
30
|
Lowe SW, Schmitt EM, Smith SW, Osborne BA
and Jacks T: p53 is required for radiation-induced apoptosis in
mouse thymocytes. Nature. 362:847–849. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Eisenberg-Lerner A, Bialik S, Simon HU and
Kimchi A: Life and death partners: Apoptosis, autophagy and the
cross-talk between them. Cell Death Differ. 16:966–975. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Crighton D, Wilkinson S, O'Prey J, Syed N,
Smith P, Harrison PR, Gasco M, Garrone O, Crook T and Ryan KM:
DRAM, a p53-induced modulator of autophagy, is critical for
apoptosis. Cell. 126:121–134. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Maiuri MC, Malik SA, Morselli E, Kepp O,
Criollo A, Mouchel PL, Carnuccio R and Kroemer G: Stimulation of
autophagy by the p53 target gene Sestrin2. Cell Cycle. 8:1571–1576.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Rosenfeldt MT, O'Prey J, Morton JP, Nixon
C, MacKay G, Mrowinska A, Au A, Rai TS, Zheng L, Ridgway R, et al:
p53 status determines the role of autophagy in pancreatic tumour
development. Nature. 504:296–300. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Han MW, Lee JC, Choi JY, Kim GC, Chang HW,
Nam HY, Kim SW and Kim SY: Autophagy inhibition can overcome
radioresistance in breast cancer cells through suppression of TAK1
activation. Anticancer Res. 34:1449–1455. 2014.PubMed/NCBI
|
|
36
|
Chen Z, Liu X and Ma S: The roles of
mitochondria in autophagic cell death. Cancer Biother Radiopharm.
31:269–276. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Qiao ZY, Lai WJ, Lin YX, Li D, Nan XH,
Wang Y, Wang H and Fang QJ: Polymer-KLAK peptide conjugates induce
cancer cell death through synergistic effects of mitochondria
damage and autophagy blockage. Bioconjug Chem. 28:1709–1721. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Danese A, Patergnani S, Bonora M,
Wieckowski MR, Previati M, Giorgi C and Pinton P: Calcium regulates
cell death in cancer: Roles of the mitochondria and
mitochondria-associated membranes (MAMs). Biochim Biophys Acta.
1858:615–627. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Kim H, Rafiuddin-Shah M, Tu HC, Jeffers
JR, Zambetti GP, Hsieh JJ and Cheng EH: Hierarchical regulation of
mitochondrion-dependent apoptosis by BCL-2 subfamilies. Nat Cell
Biol. 8:1348–1358. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Kim H, Tu HC, Ren D, Takeuchi O, Jeffers
JR, Zambetti GP, Hsieh JJ and Cheng EH: Stepwise activation of BAX
and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.
Mol Cell. 36:487–499. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Colell A, Ricci JE, Tait S, Milasta S,
Maurer U, Bouchier-Hayes L, Fitzgerald P, Guio-Carrion A,
Waterhouse NJ, Li CW, et al: GAPDH and autophagy preserve survival
after apoptotic cytochrome c release in the absence of caspase
activation. Cell. 129:983–997. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Lartigue L, Kushnareva Y, Seong Y, Lin H,
Faustin B and Newmeyer DD: Caspase-independent mitochondrial cell
death results from loss of respiration, not cytotoxic protein
release. Mol Biol Cell. 20:4871–4884. 2009. View Article : Google Scholar : PubMed/NCBI
|
