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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2018 Volume 52 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Glucocorticoid receptor overexpression slightly shifts microRNA expression patterns in triple-negative breast cancer

Dominik Buschmann, Ricardo González, Benedikt Kirchner, Claudia Mazzone, Michael W. Pfaffl, Gustav Schelling, Ortrud Steinlein, Marlene Reithmair
Pages: 1765-1776
Published online on: 27 March 2018

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Article Open Access

Long noncoding RNA LINC01296 promotes tumor growth and progression by sponging miR-5095 in human cholangiocarcinoma

Dawei Zhang, Haiyan Li, Juping Xie, Decan Jiang, Liangqi Cao, Xuewei Yang, Ping Xue, Xiaofeng Jiang
Pages: 1777-1786
Published online on: 05 April 2018

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Article Open Access

Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells

Wei Jia, Xingjun Jiang, Weidong Liu, Lei Wang, Bin Zhu, Hecheng Zhu, Xingdong Liu, Meizuo Zhong, Dan Xie, Wei Huang, Wenting Jia, Shasha Li, Xuxu Liu, Xiang Zuo, Damei Cheng, Jianwu Dai, Caiping Ren
Pages: 1787-1800
Published online on: 20 March 2018

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Article Open Access

MicroRNA-671-3p inhibits the development of breast cancer: A study based on in vitro experiments, in-house quantitative polymerase chain reaction and bioinformatics analysis

Dan-Dan Xiong, Hao Chen, Rong-Quan He, Ai-Hua Lan, Jin-Cai Zhong, Gang Chen, Zhen-Bo Feng, Kang-Lai Wei
Pages: 1801-1814
Published online on: 28 March 2018

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Article Open Access

Upregulation of E‑cadherin expression mediated by a novel dsRNA suppresses the growth and metastasis of bladder cancer cells by inhibiting β-catenin/TCF target genes

Chuanchang Li, Jiaxuan Liu, Qingsong Zhang, Kai Cui, Qiangqiang Ge, Chenghe Wang, Zhong Chen
Pages: 1815-1826
Published online on: 29 March 2018

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Article Open Access

β‑catenin nuclear translocation induced by HIF‑1α overexpression leads to the radioresistance of prostate cancer

Yong Luo, Mingchuan Li, Xuemei Zuo, Spyridon P. Basourakos, Jiao Zhang, Jiahui Zhao, Yili Han, Yunhua Lin, Yongxing Wang, Yongguang Jiang, Ling Lan
Pages: 1827-1840
Published online on: 12 April 2018

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Article Open Access

S-phase kinase-associated protein 2 is involved in epithelial-mesenchymal transition in methotrexate-resistant osteosarcoma cells

Lu Ding, Chengwei Wang, Yong Cui, Xiaoping Han, Yang Zhou, Jingping Bai, Rong Li
Pages: 1841-1852
Published online on: 29 March 2018

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Article Open Access

Autophagy inhibition enhances radiosensitivity of Eca‑109 cells via the mitochondrial apoptosis pathway

Hua Tao, Pudong Qian, Jincheng Lu, Yesong Guo, Huanfeng Zhu, Feijiang Wang
Pages: 1853-1862
Published online on: 29 March 2018

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Article Open Access

Increased level of cell-derived microparticles in the cyst fluids of odontogenic keratocysts

Qi-Wen Man, Wen-Qun Zhong, Jian-Gang Ren, Jin-Yuan Liu, Yue-Yu Zheng, Rui-Fang Li, B. Fidele Nyimi, Gang Chen, Yi-Fang Zhao, Bing Liu
Pages: 1863-1874
Published online on: 05 April 2018

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Article Open Access

Preclinical evaluation of a novel engineered recombinant human anti-CD44v6 antibody for potential use in radio-immunotherapy

Anja C. Mortensen, Diana Spiegelberg, Anna-Karin Haylock, Hans Lundqvist, Marika Nestor
Pages: 1875-1885
Published online on: 11 April 2018

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Article Open Access

LTBP2 promotes the migration and invasion of gastric cancer cells and predicts poor outcome of patients with gastric cancer

Jun Wang, Wen-Jia Liang, Guang-Tao Min, Hong-Peng Wang, Wei Chen, Nan Yao
Pages: 1886-1898
Published online on: 04 April 2018

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Article Open Access

Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation

Guiju Tang, Jianfeng Guo, Yapei Zhu, Zaiju Huang, Ting Liu, Jing Cai, Lili Yu, Zehua Wang
Pages: 1899-1911
Published online on: 29 March 2018

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Article Open Access

KIFC1, a novel potential prognostic factor and therapeutic target in hepatocellular carcinoma

Xiaowei Fu, Yaqiong Zhu, Bingbing Zheng, Yeqing Zou, Chao Wang, Peng Wu, Jun Wang, Haimin Chen, Pengcheng Du, Bo Liang, Lu Fang
Pages: 1912-1922
Published online on: 29 March 2018

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Article Open Access

Tumor-suppressing effects of microRNA-612 in bladder cancer cells by targeting malic enzyme 1 expression

Mengnan Liu, Yifan Chen, Bisheng Huang, Shiyu Mao, Keke Cai, Longsheng Wang, Xudong Yao
Pages: 1923-1933
Published online on: 29 March 2018

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Article Open Access

Decreased expression of SFRP2 promotes development of the pituitary corticotroph adenoma by upregulating Wnt signaling

Jie Ren, Fangfang Jian, Hong Jiang, Yuhao Sun, Sijian Pan, Changwei Gu, Xiao Chen, Weiqing Wang, Guang Ning, Liuguan Bian, Qingfang Sun
Pages: 1934-1946
Published online on: 03 April 2018

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Article

Metabolome analysis of esophageal cancer tissues using capillary electrophoresis-time-of-flight mass spectrometry

Masanori Tokunaga, Kenjiro Kami, Soji Ozawa, Junya Oguma, Akihito Kazuno, Hayato Miyachi, Yoshiaki Ohashi, Masatoshi Kusuhara, Masanori Terashima
Pages: 1947-1958
Published online on: 28 March 2018

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Article

Arsenic disulfide‑induced apoptosis and its potential mechanism in two‑ and three‑dimensionally cultured human breast cancer MCF‑7 cells

Yuxue Zhao, Kenji Onda, Bo Yuan, Sachiko Tanaka, Anna Kiyomi, Kentaro Sugiyama, Munetoshi Sugiura, Norio Takagi, Toshihiko Hirano
Pages: 1959-1971
Published online on: 04 April 2018

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Article

Mutational burden of resectable pancreatic cancer, as determined by whole transcriptome and whole exome sequencing, predicts a poor prognosis

Elisa Grassi, Sandra Durante, Annalisa Astolfi, Giuseppe Tarantino, Valentina Indio, Eva Freier, Silvia Vecchiarelli, Claudio Ricci, Riccardo Casadei, Francesca Formica, Daria Filippini, Francesca Comito, Carla Serra, Donatella Santini, Antonietta D' Errico, Francesco Minni, Guido Biasco, Mariacristina Di Marco
Pages: 1972-1980
Published online on: 29 March 2018

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Article

Phosphatidylserine-exposing cells contribute to the hypercoagulable state in patients with multiple myeloma

Li Guo, Dongxia Tong, Muxin Yu, Yan Zhang, Tao Li, Chunxu Wang, Peng Zhou, Jiaqi Jin, Baorong Li, Yingmiao Liu, Ruipeng Liu, Valerie A. Novakovic, Zengxiang Dong, Ye Tian, Junjie Kou, Yayan Bi, Jin Zhou, Jialan Shi
Pages: 1981-1990
Published online on: 03 April 2018

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Article

Biotinylation enhances the anticancer effects of 15d‑PGJ2 against breast cancer cells

Christelle Colin, Maxime Meyer, Claudia Cerella, Alexandra Kleinclauss, Gérald Monard, Michel Boisbrun, Marc Diederich, Stéphane Flament, Isabelle Grillier-Vuissoz, Sandra Kuntz
Pages: 1991-2000
Published online on: 28 March 2018

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Article

Silencing of ASPP2 promotes the proliferation, migration and invasion of triple-negative breast cancer cells via the PI3K/AKT pathway

Tianqi Wu, Hongming Song, Dan Xie, Bingkun Zhao, Hui Xu, Chenyang Wu, Kaiyao Hua, Yijun Deng, Changle Ji, Jiashu Hu, Lin Fang
Pages: 2001-2010
Published online on: 20 March 2018

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Article

PPP2R2D, a regulatory subunit of protein phosphatase 2A, promotes gastric cancer growth and metastasis via mechanistic target of rapamycin activation

Shijun Yu, Li Li, Qiong Wu, Ning Dou, Yandong Li, Yong Gao
Pages: 2011-2020
Published online on: 20 March 2018

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Article

Chaperonin-containing T‑complex protein 1 subunit 8 promotes cell migration and invasion in human esophageal squamous cell carcinoma by regulating α-actin and β-tubulin expression

Xiaojing Yang, Hanru Ren, Yuhui Shao, Yi Sun, Lihua Zhang, Hongling Li, Xiulong Zhang, Xinmiao Yang, Weiwei Yu, Jie Fu
Pages: 2021-2030
Published online on: 27 March 2018

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Article

p38 inhibitor inhibits the apoptosis of cowanin-treated human colorectal adenocarcinoma cells

Nittiya Chowchaikong, Sirinun Nilwarangkoon, Surat Laphookhieo, Chantra Tanunyutthawongse, Ramida Watanapokasin
Pages: 2031-2040
Published online on: 03 April 2018

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Article

Combination of TP53 and AGR3 to distinguish ovarian high-grade serous carcinoma from low-grade serous carcinoma

Chunping Qiu, Yu Wang, Xiao Wang, Qing Zhang, Yinuo Li, Ying Xu, Chengjuan Jin, Hualei Bu, Wenxin Zheng, Xingsheng Yang, Nan Lu, Beihua Kong
Pages: 2041-2050
Published online on: 04 April 2018

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Article

Synergistic anti-hepatoma effect of bufalin combined with sorafenib via mediating the tumor vascular microenvironment by targeting mTOR/VEGF signaling

Haiyong Wang, Chenyue Zhang, Huiying Chi, Zhiqiang Meng
Pages: 2051-2060
Published online on: 02 April 2018

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Article

Cotylenin A and tyrosine kinase inhibitors synergistically inhibit the growth of chronic myeloid leukemia cells

Fumiyoshi Ikejiri, Yoshio Honma, Takahiro Okada, Takeshi Urano, Junji Suzumiya
Pages: 2061-2068
Published online on: 02 April 2018

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Article

Differential expression of Oct3/4 in human breast cancer and normal tissues

Feng-Qi Zhao, Yogi Misra, Da-Biao Li, Marilyn P. Wadsworth, David Krag, Donald Weaver, Joseph Tessitore, Da-Wei Li, Guo Zhang, Qing Tian, Katie Buss
Pages: 2069-2078
Published online on: 29 March 2018

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Article

Expression and clinical significance of PD‑1 in hepatocellular carcinoma tissues detected by a novel mouse anti-human PD‑1 monoclonal antibody

Ziwei Li, Bin Li, Dan Peng, Haiyan Xing, Guanying Wang, Pan Li, Jiming Wang, George Ye, Jianhong Chen
Pages: 2079-2092
Published online on: 04 April 2018

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Article

Effect of HOXA6 on the proliferation, apoptosis, migration and invasion of colorectal cancer cells

Shasha Wu, Feixiang Wu, Zheng Jiang
Pages: 2093-2100
Published online on: 02 April 2018

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Article

The inhibition of heme oxygenase-1 enhances the chemosensitivity and suppresses the proliferation of pancreatic cancer cells through the SHH signaling pathway

Liang Han, Jie Jiang, Qingyong Ma, Zheng Wu, Zheng Wang
Pages: 2101-2109
Published online on: 05 April 2018

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Article

Rapid point-of-care testing for epidermal growth factor receptor gene mutations in patients with lung cancer using cell-free DNA from cytology specimen supernatants

Shiho Asaka, Akihiko Yoshizawa, Kazusa Saito, Yukihiro Kobayashi, Hiroshi Yamamoto, Tatsuya Negishi, Rie Nakata, Kazuyuki Matsuda, Akemi Yamaguchi, Takayuki Honda
Pages: 2110-2118
Published online on: 27 March 2018

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Article

Lutein inhibits proliferation, invasion and migration of hypoxic breast cancer cells via downregulation of HES1

Yuan Li, Yuekun Zhang, Xiaosa Liu, Mingchen Wang, Peng Wang, Jianbo Yang, Shanfeng Zhang
Pages: 2119-2129
Published online on: 23 March 2018

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Article

FOXD1 is targeted by miR-30a-5p and miR-200a-5p and suppresses the proliferation of human ovarian carcinoma cells by promoting p21 expression in a p53-independent manner

Yu Wang, Chunping Qiu, Nan Lu, Zhaojian Liu, Chengjuan Jin, Chenggong Sun, Hualei Bu, Hongfeng Yu, Samina Dongol, Beihua Kong
Pages: 2130-2142
Published online on: 04 April 2018

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Article

Antitumour effects and mechanisms of action of the panHER inhibitor, dacomitinib, alone and in combination with the STAT3 inhibitor, S3I-201, in human sarcoma cell lines

Xiaochun Wang, David Goldstein, Philip J. Crowe, Jia-Lin Yang
Pages: 2143-2154
Published online on: 27 March 2018

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Article

Different splicing isoforms of ERCC1 affect the expression of its overlapping genes CD3EAP and PPP1R13L, and indicate a potential application in non-small cell lung cancer treatment

Guopei Zhang, Ping Xue, Su Cui, Tao Yu, Mingyang Xiao, Qianye Zhang, Yuan Cai, Cuihong Jin, Jinghua Yang, Shengwen Wu, Xiaobo Lu
Pages: 2155-2165
Published online on: 29 March 2018

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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