|
1
|
Jemal A, Siegel R, Xu J and Ward E: Cancer
statistics, 2010. CA Cancer J Clin. 60:277–300. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Iseki Y, Shibutani M, Maeda K, Nagahara H,
Ohtani H, Sugano K, Ikeya T, Muguruma K, Tanaka H, Toyokawa T, et
al: Impact of the preoperative controlling nutritional status
(CONUT) score on the survival after curative surgery for colorectal
cancer. PLoS One. 10:e01324882015. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Liu H, Ren G, Wang T, Chen Y, Gong C, Bai
Y, Wang B, Qi H, Shen J, Zhu L, et al: Aberrantly expressed Fra-1
by IL-6/STAT3 transactivation promotes colorectal cancer
aggressiveness through epithelial-mesenchymal transition.
Carcinogenesis. 36:459–468. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Grünert S, Jechlinger M and Beug H:
Diverse cellular and molecular mechanisms contribute to epithelial
plasticity and metastasis. Nat Rev Mol Cell Biol. 4:657–665. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Yilmaz M and Christofori G: EMT, the
cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev.
28:15–33. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
König K, Meder L, Kröger C, Diehl L,
Florin A, Rommerscheidt-Fuss U, Kahl P, Wardelmann E, Magin TM,
Buettner R, et al: Loss of the keratin cytoskeleton is not
sufficient to induce epithelial mesenchymal transition in a novel
KRAS driven sporadic lung cancer mouse model. PLoS One.
8:e579962013. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Jockusch BM, Murk K and Rothkegel M: The
profile of profilins. Rev Physiol Biochem Pharmacol. 159:131–149.
2007.PubMed/NCBI
|
|
8
|
Witke W, Podtelejnikov AV, Di Nardo A,
Sutherland JD, Gurniak CB, Dotti C and Mann M: In mouse brain
profilin I and profilin II associate with regulators of the
endocytic pathway and actin assembly; EMBO J. 17:967–976. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Ma CY, Zhang CP, Zhong LP, Pan HY, Chen
WT, Wang LZ, Andrew OW, Ji T and Han W: Decreased expression of
profilin 2 in oral squamous cell carcinoma and its
clinicopathological implications. Oncol Rep. 26:813–823.
2011.PubMed/NCBI
|
|
10
|
Greene FL: Current TNM staging of
colorectal cancer. Lancet Oncol. 8:572–573. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
12
|
Castosa R, Martinez-Iglesias O, Roca-Lema
D, Casas-Pais A, Díaz-Díaz A, Iglesias P, Santamarina I, Graña B,
Calvo L, Valladares-Ayerbes M, et al: Hakai overexpression
effectively induces tumour progression and metastasis in vivo. Sci
Rep. 8:3466–3475. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Findlay VJ, Wang C, Watson DK and Camp ER:
Epithelial-to-mesenchymal transition and the cancer stem cell
phenotype: Insights from cancer biology with therapeutic
implications for colorectal cancer. Cancer Gene Ther. 21:181–187.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Ferron F, Rebowski G, Lee SH and Dominguez
R: Structural basis for the recruitment of profilin-actin complexes
during filament elongation by Ena/VASP. EMBO J. 26:4597–4606. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Mouneimne G, Hansen SD, Selfors LM, Petrak
L, Hickey MM, Gallegos LL, Simpson KJ, Lim J, Gertler FB, Hartwig
JH, et al: Differential remodeling of actin cytoskeleton
architecture by profilin isoforms leads to distinct effects on cell
migration and invasion. Cancer Cell. 22:615–630. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Takebe T, Enomura M, Yoshizawa E, Kimura
M, Koike H, Ueno Y, Matsuzaki T, Yamazaki T, Toyohara T, Osafune K,
et al: Vascularized and complex organ buds from diverse tissues via
mesenchymal cell-driven condensation. Cell Stem Cell. 16:556–565.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Kanaan Z, Qadan M, Eichenberger MR and
Galandiuk S: The actin-cytoskeleton pathway and its potential role
in inflammatory bowel disease-associated human colorectal cancer.
Genet Test Mol Biomarkers. 14:347–353. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Schlüter K, Jockusch BM and Rothkegel M:
Profilins as regulators of actin dynamics. Biochim Biophys Acta.
1359:97–109. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Liu J, Wu Y, Wang Q, Liu X, Liao X and Pan
J: Bioinformatic analysis of PFN2 dysregulation and its prognostic
value in head and neck squamous carcinoma. Future Oncol.
14:449–459. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Cui XB, Zhang SM, Xu YX, Dang HW, Liu CX,
Wang LH, Yang L, Hu JM, Liang WH, Jiang JF, et al: PFN2, a novel
marker of unfavorable prognosis, is a potential therapeutic target
involved in esophageal squamous cell carcinoma. J Transl Med.
14:137–152. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Yan J, Ma C and Gao Y: MicroRNA-30a-5p
suppresses epithelial-mesenchymal transition by targeting
profilin-2 in high invasive non-small cell lung cancer cell lines.
Oncol Rep. 37:3146–3154. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Ding Z and Roy P: Profilin-1 versus
profilin-2: Two faces of the same coin. Breast Cancer Res.
15:311–312. 2013. View
Article : Google Scholar
|
|
23
|
Cheng YJ, Zhu ZX, Zhou JS, Hu ZQ, Zhang
JP, Cai QP and Wang LH: Silencing profilin-1 inhibits gastric
cancer progression via integrin β1/focal adhesion kinase pathway
modulation. World J Gastroenterol. 21:2323–2335. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Karamchandani JR, Gabril MY, Ibrahim R,
Scorilas A, Filter E, Finelli A, Lee JY, Ordon M, Pasic M,
Romaschin AD, et al: Profilin-1 expression is associated with high
grade and stage and decreased disease-free survival in renal cell
carcinoma. Hum Pathol. 46:673–680. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Coumans JV, Gau D, Poljak A, Wasinger V,
Roy P and Moens PD: Profilin-1 overexpression in MDA-MB-231 breast
cancer cells is associated with alterations in proteomics
biomarkers of cell proliferation, survival, and motility as
revealed by global proteomics analyses. OMICS. 18:778–791. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Liang JW, Shi ZZ, Shen TY, Che X, Wang Z,
Shi SS, Xu X, Cai Y, Zhao P, Wang CF, et al: Identification of
genomic alterations in pancreatic cancer using array-based
comparative genomic hybridization. PLoS One. 9:e1146162014.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Alkam D, Feldman EZ, Singh A and Kiaei M:
Profilin1 biology and its mutation, actin(g) in disease. Cell Mol
Life Sci. 74:967–981. 2017. View Article : Google Scholar :
|
|
28
|
Tang YN, Ding WQ, Guo XJ, Yuan XW, Wang DM
and Song JG: Epigenetic regulation of Smad2 and Smad3 by profilin-2
promotes lung cancer growth and metastasis. Nat Commun.
6:8230–8239. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Tsai JH and Yang J: Epithelial-mesenchymal
plasticity in carcinoma metastasis. Genes Dev. 27:2192–2206. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Savagner P: Epithelial-mesenchymal
transitions: From cell plasticity to concept elasticity. Curr Top
Dev Biol. 112:273–300. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Medici D, Hay ED and Olsen BR: Snail and
Slug promote epithelial-mesenchymal transition through
beta-catenin-T-cell factor-4-dependent expression of transforming
growth factor-beta3. Mol Biol Cell. 19:4875–4887. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Qiao Y, Chen J, Lim YB, Finch-Edmondson
ML, Seshachalam VP, Qin L, Jiang T, Low BC, Singh H, Lim CT, et al:
YAP regulates actin dynamics through ARHGAP29 and promotes
metastasis. Cell Reports. 19:1495–1502. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Wieczorek K, Wiktorska M, Sacewicz-Hofman
I, Boncela J, Lewiński A, Kowalska MA and Niewiarowska J: Filamin A
upregulation correlates with Snail-induced epithelial to
mesenchymal transition (EMT) and cell adhesion but its inhibition
increases the migration of colon adenocarcinoma HT29 cells. Exp
Cell Res. 359:163–170. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Izdebska M, Gagat M and Grzanka A:
Overexpression of lamin B1 induces mitotic catastrophe in colon
cancer LoVo cells and is associated with worse clinical outcomes.
Int J Oncol. 52:89–102. 2018.
|
