Journal Articles
Review
Overview of mitochondrial germline variants and mutations in human disease: Focus on breast cancer (Review)
Silvia Jiménez-Morales, Carlos J. Pérez-Amado, Elizabeth Langley, Alfredo Hidalgo-Miranda
Pages: 923-936 Published online on: 04 July 2018
Article
ZIC1 acts a tumor suppressor in breast cancer by targeting survivin
Wei Han, Fang Cao, Xiao-Jiao Gao, Hua-Bing Wang, Fang Chen, Si-Jian Cai, Cong Zhang, Yong-Wei Hu, Jun Ma, Xing Gu, Hou-Zhong Ding
Pages: 937-948 Published online on: 21 June 2018
Article
The enhanced antitumour response of pimozide combined with the IDO inhibitor L‑MT in melanoma
Huijie Jia, Wenjing Ren, Yuchen Feng, Tian Wei, Mengmeng Guo, Jing Guo, Jingjing Zhao, Xiangfeng Song, Mingyong Wang, Tiesuo Zhao, Hui Wang, Zhiwei Feng, Zhongwei Tian
Pages: 949-960 Published online on: 06 July 2018
Article
KRAB zinc-finger protein 382 regulates epithelial-mesenchymal transition and functions as a tumor suppressor, but is silenced by CpG methylation in gastric cancer
Lijiao Pei, Xiaoqian He, Shuman Li, Ran Sun, Qin Xiang, Guosheng Ren, Tingxiu Xiang
Pages: 961-972 Published online on: 19 June 2018
Article
NLRP3 in human glioma is correlated with increased WHO grade, and regulates cellular proliferation, apoptosis and metastasis via epithelial-mesenchymal transition and the PTEN/AKT signaling pathway
Xiao-Feng Yin, Qiong Zhang, Zhuo-Yu Chen, Hai-Fang Wang, Xin Li, Hong-Xia Wang, Hai-Xia Li, Chun-Min Kang, Shuai Chu, Kai-Fei Li, Yao Li, Yu-Rong Qiu
Pages: 973-986 Published online on: 12 July 2018
Article
Epoxymicheliolide, a novelguaiane-type sesquiterpene lactone, inhibits NF‑κB/COX‑2 signaling pathways by targeting leucine 281 and leucine 25 in IKKβ in renal cell carcinoma
Jiabin Zhu, Jun Zhao, Zhenlong Yu, Sandeep Shrestha, Jing Song, Wenwen Liu, Wen Lan, Jinshan Xing, Shuang Liu, Chen Chen, Momo Cao, Xiuzhen Sun, Qi Wang, Xishuang Song
Pages: 987-1000 Published online on: 29 June 2018
Article
Effects of a checkpoint kinase inhibitor, AZD7762, on tumor suppression and bone remodeling
Luqi Wang, Yue Wang, Andy Chen, Aydin Jalali, Shengzhi Liu, Yunxia Guo, Sungsoo Na, Harikrishna Nakshatri, Bai-Yan Li, Hiroki Yokota
Pages: 1001-1012 Published online on: 13 July 2018
Article
Exosome-mediated transfer of lncRNA‑SNHG14 promotes trastuzumab chemoresistance in breast cancer Retraction in /10.3892/ijo.2022.5382
Huaying Dong, Wei Wang, Ru Chen, Yu Zhang, Kejian Zou, Mulin Ye, Xionghui He, Fan Zhang, Jing Han
Pages: 1013-1026 Published online on: 03 July 2018
Article
Fordin: A novel type I ribosome inactivating protein from Vernicia fordii modulates multiple signaling cascades leading to anti-invasive and pro-apoptotic effects in cancer cells in vitro
Weili Lu, Yingji Mao, Xue Chen, Jun Ni, Rui Zhang, Yuting Wang, Jun Wang, Lifang Wu
Pages: 1027-1042 Published online on: 04 July 2018
Article
NT21MP negatively regulates paclitaxel-resistant cells by targeting miR‑155‑3p and miR‑155-5p via the CXCR4 pathway in breast cancer
Yueyue Wang, Lei Yan, Lingyu Zhang, Henan Xu, Tiantian Chen, Yu Li, Haifeng Wang, Sulian Chen, Wenrui Wang, Changjie Chen, Qingling Yang
Pages: 1043-1054 Published online on: 09 July 2018
Article
ABT737 reverses cisplatin resistance by targeting glucose metabolism of human ovarian cancer cells
Yunjie Xu, Weinan Gao, Yong Zhang, Shanshan Wu, Yanan Liu, Xinyue Deng, Lili Xie, Jiayan Yang, Huimei Yu, Jing Su, Liankun Sun
Pages: 1055-1068 Published online on: 09 July 2018
Article
LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells in vitro and in vivo through enhancing PDGFRβ signaling Corrigendum in /10.3892/ijo.2019.4769 Corrigendum in /10.3892/ijo.2022.5305
Qungen Xiao, Minhai Dong, Fangling Cheng, Feng Mao, Weifeng Zong, Kang Wu, Heping Wang, Ruifan Xie, Baofeng Wang, Ting Lei, Dongsheng Guo
Pages: 1069-1082 Published online on: 16 July 2018
Article
Identifying autophagy gene-associated module biomarkers through construction and analysis of an autophagy-mediated ceRNA‑ceRNA interaction network in colorectal cancer
Kun Qian, Huiying Huang, Jing Jiang, Dahua Xu, Shengnan Guo, Ying Cui, Hao Wang, Liqiang Wang, Kongning Li
Pages: 1083-1093 Published online on: 18 June 2018
Article
lncRNA-ATB functions as a competing endogenous RNA to promote YAP1 by sponging miR-590-5p in malignant melanoma
Kuanhou Mou, Bo Liu, Meiling Ding, Xin Mu, Dan Han, Yan Zhou, Li-Juan Wang
Pages: 1094-1104 Published online on: 25 June 2018
Article
Liposomal paclitaxel induces fewer hematopoietic and cardiovascular complications than bioequivalent doses of Taxol
Shih-Ting Huang, Yi‑Ping Wang, Yen-Hui Chen, Chin-Tarng Lin, Wen-Shan Li, Han-Chung Wu
Pages: 1105-1117 Published online on: 21 June 2018
Article
Loss of profilin 2 contributes to enhanced epithelial-mesenchymal transition and metastasis of colorectal cancer
Hui Zhang, Weiqiang Yang, Jinlong Yan, Kaiping Zhou, Boshun Wan, Peidong Shi, Yueyu Chen, Songbing He, Dechun Li
Pages: 1118-1128 Published online on: 09 July 2018
Article
Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3
Bowei Li, Xiaoxun Chen, Wenbin Yang, Jingliang He, Ke He, Zhenglin Xia, Jinqian Zhang, Guoan Xiang
Pages: 1129-1137 Published online on: 28 June 2018
Article
High COX-2 expression contributes to a poor prognosis through the inhibition of chemotherapy-induced senescence in nasopharyngeal carcinoma
Chen Shi, Yongjun Guan, Liang Zeng, Guizhu Liu, Yinghong Zhu, He Xu, Yichen Lu, Jiabin Liu, Jiaojiao Guo, Xiangling Feng, Xinying Zhao, Weihong Jiang, Guancheng Li, Guiyuan Li, Yun Dai, Fengyan Jin, Wei Li, Wen Zhou
Pages: 1138-1148 Published online on: 29 June 2018
Article
Effect of ABT-888 on the apoptosis, motility and invasiveness of BRAFi-resistant melanoma cells
Federica Fratangelo, Rosa Camerlingo, Maria Vincenza Carriero, Giuseppe Pirozzi, Giuseppe Palmieri, Giusy Gentilcore, Concetta Ragone, Michele Minopoli, Paolo Antonio Ascierto, Maria Letizia Motti
Pages: 1149-1159 Published online on: 27 June 2018
Article
Rhaponticin decreases the metastatic and angiogenic abilities of cancer cells via suppression of the HIF‑1α pathway
Aeyung Kim, Jin Yeul Ma
Pages: 1160-1170 Published online on: 11 July 2018
Article
Psoriasin overexpression confers drug resistance to cisplatin by activating ERK in gastric cancer
Liting Li, Yuxin Cui, Lin Ye, Zehang Zhao, Wen G. Jiang, Jiafu Ji
Pages: 1171-1182 Published online on: 26 June 2018
Article
Silencing GOLPH3 gene expression reverses resistance to cisplatin in HT29 colon cancer cells via multiple signaling pathways
Zhi-Ping Zhou, Lin-Pei Wang, Zhong-Shi Hong, Cheng-Zhi Qiu, Ming-Zhen Wang, Zhi-Xiong Chen, Long-Feng Tang, Wai-Shi Yu, Chun-Xiao Wang
Pages: 1183-1192 Published online on: 05 July 2018
Article
Modulation of the tumor microenvironment by intratumoral administration of IMO-2125, a novel TLR9 agonist, for cancer immunotherapy
Daqing Wang, Wayne Jiang, Fugang Zhu, Xianzhi Mao, Sudhir Agrawal
Pages: 1193-1203 Published online on: 27 June 2018
Article
MicroRNA-494 acts as a tumor suppressor in pancreatic cancer, inhibiting epithelial-mesenchymal transition, migration and invasion by binding to SDC1
Ying Yang, Xiong Tao, Chun-Bo Li, Chang-Miao Wang
Pages: 1204-1214 Published online on: 19 June 2018
Article
Tumor suppressor LKB1 inhibits the progression of gallbladder carcinoma and predicts the prognosis of patients with this malignancy
Ming-Tai Hu, Jing-Han Wang, Yong Yu, Chen Liu, Bin Li, Qing-Bao Cheng, Xiao-Qing Jiang
Pages: 1215-1226 Published online on: 02 July 2018
Article
Long non‑coding RNA 00152 functions as a competing endogenous RNA to regulate NRP1 expression by sponging with miRNA‑206 in colorectal cancer
Zhuan-Peng Chen, Jian-Chang Wei, Qiang Wang, Ping Yang, Wang-Lin Li, Feng He, Hua‑Cui Chen, He Hu, Jun-Bin Zhong, Jie Cao
Pages: 1227-1236 Published online on: 22 June 2018
Article
Identification of cisplatin sensitizers through high-throughput combinatorial screening
Yichen Sun, Weiye Jiang, Wenhua Lu, Ming Song, Kaiyan Liu, Ping Chen, Allison Chang, Jianhua Ling, Paul J. Chiao, Yumin Hu, Peng Huang
Pages: 1237-1246 Published online on: 19 June 2018
Article
Decreased expression of miR‑490‑3p in colorectal cancer predicts poor prognosis and promotes cell proliferation and invasion by targeting RAB14
Bo Wang, Mujun Yin, Cheng Cheng, Hongpeng Jiang, Kewei Jiang, Zhanlong Shen, Yingjiang Ye, Shan Wang
Pages: 1247-1256 Published online on: 19 June 2018
Article
The antioxidant, aged garlic extract, exerts cytotoxic effects on wild-type and multidrug-resistant human cancer cells by altering mitochondrial permeability
Shinji Ohkubo, Lisa Dalla Via, Silvia Grancara, Yuta Kanamori, Aída Nelly García-Argáez, Gianluca Canettieri, Paolo Arcari, Antonio Toninello, Enzo Agostinelli
Pages: 1257-1268 Published online on: 22 June 2018
Article
Tristetraprolin activation by resveratrol inhibits the proliferation and metastasis of colorectal cancer cells
Se-Ra Lee, Hua Jin, Won-Tae Kim, Won-Jung Kim, Sung Zoo Kim, Sun-Hee Leem, Soo Mi Kim
Pages: 1269-1278 Published online on: 25 June 2018
Article
Polyphyllin I inhibits invasion and epithelial-mesenchymal transition via CIP2A/PP2A/ERK signaling in prostate cancer
Xuewen Liu, Zhiting Sun, Jikun Deng, Jun Liu, Kaihuai Ma, Yuan Si, Te Zhang, Tingting Feng, Ying Liu, Yan Tan
Pages: 1279-1288 Published online on: 29 June 2018
Article
Promoted delivery of salinomycin sodium to lung cancer cells by dual targeting PLGA hybrid nanoparticles
Jie Zhou, Jin Sun, Huaiwen Chen, Qing Peng
Pages: 1289-1300 Published online on: 06 July 2018
Article
BECN1-knockout impairs tumor growth, migration and invasion by suppressing the cell cycle and partially suppressing the epithelial-mesenchymal transition of human triple-negative breast cancer cells
Cheng-Lin Wu, Shi‑Meng Zhang, Li Lin, Shan-Shan Gao, Kai-Fei Fu, Xiao-Dan Liu, Yan Liu, Li-Jun Zhou, Ping-Kun Zhou
Pages: 1301-1312 Published online on: 05 July 2018
Article
Prolonged survival of patients with colorectal cancer is associated with a higher regucalcin gene expression: Overexpression of regucalcin suppresses the growth of human colorectal carcinoma cells in vitro
Masayoshi Yamaguchi, Satoru Osuka, Tomiyasu Murata
Pages: 1313-1322 Published online on: 28 June 2018
Article
Silencing Ubc9 expression suppresses osteosarcoma tumorigenesis and enhances chemosensitivity to HSV-TK/GCV by regulating connexin 43 SUMOylation
Dianying Zhang, Kai Yu, Zhong Yang, Yanxia Li, Xiaofang Ma, Xiyun Bian, Fengting Liu, Lili Li, Xiaozhi Liu, Wenhan Wu
Pages: 1323-1331 Published online on: 21 June 2018
Article
MicroRNA-381 reduces inflammation and infiltration of macrophages in polymyositis via downregulating HMGB1
Yutao Liu, Yuan Gao, Jing Yang, Changhe Shi, Yanlin Wang, Yuming Xu
Pages: 1332-1342 Published online on: 29 June 2018
Article
Curcumin attenuates resistance to irinotecan via induction of apoptosis of cancer stem cells in chemoresistant colon cancer cells
Pengfei Su, Yong Yang, Guoxin Wang, Xiaowu Chen, Yongle Ju
Pages: 1343-1353 Published online on: 29 June 2018
Article
Biological effects of BMP7 on small-cell lung cancer cells and its bone metastasis
Weiwei Shen, Hailin Pang, Bo Xin, Lian Duan, Lili Liu, Helong Zhang
Pages: 1354-1362 Published online on: 04 July 2018
Article
Active fraction of clove induces apoptosis via PI3K/Akt/mTOR-mediated autophagy in human colorectal cancer HCT-116 cells
Minghua Liu, Ge Zhao, Dan Zhang, Weixiao An, Honglin Lai, Xiaofang Li, Shousong Cao, Xiukun Lin
Pages: 1363-1373 Published online on: 02 July 2018
Article
