|
1
|
Vargo MM: Brain tumors and metastases.
Phys Med Rehabil Clin N Am. 28:115–141. 2017. View Article : Google Scholar
|
|
2
|
Giese A, Bjerkvig R, Berens ME and
Westphal M: Cost of migration: Invasion of malignant gliomas and
implications for treatment. J Clin Oncol. 21:1624–1636. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Hamilton JD, Rapp M, Schneiderhan T, Sabel
M, Hayman A, Scherer A, Kröpil P, Budach W, Gerber P, Kretschmar U,
et al: Glioblastoma multiforme metastasis outside the CNS: Three
case reports and possible mechanisms of escape. J Clin Oncol. 32,
e80(e84)2014
|
|
4
|
Burger PC, Heinz ER, Shibata T and
Kleihues P: Topographic anatomy and CT correlations in the
untreated glioblastoma multiforme. J Neurosurg. 68:698–704. 1988.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Berens ME and Giese A: ‘...those left
behind.’ Biology and oncology of invasive glioma cells. Neoplasia.
1:208–219. 1999. View Article : Google Scholar
|
|
6
|
Stupp R, Mason WP, van den Bent MJ, Weller
M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn
U, et al European Organisation for Research and Treatment of Cancer
Brain Tumor and Radiotherapy Groups; National Cancer Institute of
Canada Clinical Trials Group: Radiotherapy plus concomitant and
adjuvant temozolomide for glioblastoma. N Engl J Med. 352:987–996.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Johnson DR and O’Neill BP: Glioblastoma
survival in the United States before and during the temozolomide
era. J Neurooncol. 107:359–364. 2012. View Article : Google Scholar
|
|
8
|
Cuddapah VA, Robel S, Watkins S and
Sontheimer H: A neurocentric perspective on glioma invasion. Nat
Rev Neurosci. 15:455–465. 2014. View
Article : Google Scholar : PubMed/NCBI
|
|
9
|
Shibamoto Y, Miyakawa A, Otsuka S and
Iwata H: Radiobiology of hypofractionated stereotactic
radiotherapy: What are the optimal fractionation schedules? J
Radiat Res (Tokyo). 57(Suppl 1): pp. i76–i82. 2016, View Article : Google Scholar
|
|
10
|
Wild-Bode C, Weller M, Rimner A, Dichgans
J and Wick W: Sublethal irradiation promotes migration and
invasiveness of glioma cells: Implications for radiotherapy of
human glioblastoma. Cancer Res. 61:2744–2750. 2001.PubMed/NCBI
|
|
11
|
Kil WJ, Tofilon PJ and Camphausen K:
Post-radiation increase in VEGF enhances glioma cell motility in
vitro. Radiat Oncol. 7:252012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Floyd NS, Woo SY, Teh BS, Prado C, Mai WY,
Trask T, Gildenberg PL, Holoye P, Augspurger ME, Carpenter LS, et
al: Hypofractionated intensity-modulated radiotherapy for primary
glioblastoma multiforme. Int J Radiat Oncol Biol Phys. 58:721–726.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Hingorani M, Colley WP, Dixit S and Beavis
AM: Hypofractionated radiotherapy for glioblastoma: Strategy for
poor-risk patients or hope for the future? Br J Radiol. 85:pp.
e770–e781. 2012, View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Cancer Genome Atlas and Research Network:
Comprehensive genomic characterization defines human glioblastoma
genes and core pathways. Nature. 455:1061–1068. 2008. View Article : Google Scholar
|
|
15
|
Fan QW and Weiss WA: Targeting the
RTK-PI3K-mTOR axis in malignant glioma: Overcoming resistance. Curr
Top Microbiol Immunol. 347:279–296. 2010.PubMed/NCBI
|
|
16
|
Georgakis GV, Li Y, Rassidakis GZ,
Medeiros LJ, Mills GB and Younes A: Inhibition of the
phosphatidylinositol-3 kinase/Akt promotes G1 cell cycle arrest and
apoptosis in Hodgkin lymphoma. Br J Haematol. 132:503–511.
2006.PubMed/NCBI
|
|
17
|
Westhoff MA, Karpel-Massler G, Brühl O,
Enzenmüller S, La Ferla-Brühl K, Siegelin MD, Nonnenmacher L and
Debatin KM: A critical evaluation of PI3K inhibition in
glioblastoma and neuroblastoma therapy. Mol Cell Ther. 2:322004.
View Article : Google Scholar
|
|
18
|
Wen PY, Lee EQ, Reardon DA, Ligon KL and
Alfred Yung WK: Current clinical development of PI3K pathway
inhibitors in glioblastoma. Neuro Oncol. 14:819–829. 2002.
View Article : Google Scholar
|
|
19
|
Ströbele S, Schneider M, Schneele L,
Siegelin MD, Nonnenmacher L, Zhou S, Karpel-Massler G, Westhoff MA,
Halatsch ME and Debatin KM: A potential role for the inhibition of
PI3K signaling in glioblastoma therapy. PLoS One. 10:pp.
e01316702015, View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Langhans J, Schneele L, Trenkler N, von
Bandemer H, Nonnenmacher L, Karpel-Massler G, Siegelin MD, Zhou S,
Halatsch ME, Debatin KM, et al: The effects of PI3K-mediated
signalling on glioblastoma cell behaviour. Oncogenesis. 6:3982017.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Westhoff MA, Zhou S, Nonnenmacher L,
Karpel-Massler G, Jennewein C, Schneider M, Halatsch ME, Carragher
NO, Baumann B, Krause A, et al: Inhibition of NF-kappaB signaling
ablates the invasive phenotype of glioblastoma. Mol Cancer Res.
11:1611–1623. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Westhoff MA, Zhou S, Bachem MG, Debatin KM
and Fulda S: Identification of a novel switch in the dominant forms
of cell adhesion-mediated drug resistance in glioblastoma cells.
Oncogene. 27:5169–5181. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Fowler JF: The linear-quadratic formula
and progress in fractionated radiotherapy. Br J Radiol. 62:679–694.
1989. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Giagkousiklidis S, Vogler M, Westhoff MA,
Kasperczyk H, Debatin KM and Fulda S: Sensitization for
gamma-irradiation- induced apoptosis by second mitochondria-derived
activator of caspase. Cancer Res. 65:10502–10513. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Facchino S, Abdouh M and Bernier G: Brain
cancer stem cells: current status on glioblastoma multiforme.
Cancers (Basel). 3:1777–1797. 2011. View Article : Google Scholar
|
|
26
|
Schneider M, Ströbele S, Nonnenmacher L,
Siegelin MD, Tepper M, Stroh S, Hasslacher S, Enzenmüller S,
Strauss G, Baumann B, et al: A paired comparison between
glioblastoma ‘stem cells’ and differentiated cells. Int J Cancer.
138:1709–1718. 2016. View Article : Google Scholar
|
|
27
|
Beier D, Schulz JB and Beier CP:
Chemoresistance of glioblastoma cancer stem cells - much more
complex than expected. Mol Cancer. 10:1282011. View Article : Google Scholar :
|
|
28
|
Alphonse G, Maalouf M, Battiston-Montagne
P, Ardail D, Beuve M, Rousson R, Taucher-Scholz G, Fournier C and
Rodriguez-Lafrasse C: p53-independent early and late apoptosis is
mediated by ceramide after exposure of tumor cells to photon or
carbon ion irradiation. BMC Cancer. 13:1512013. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Cordes N, Hansmeier B, Beinke C, Meineke V
and van Beuningen D: Irradiation differentially affects substratum-
dependent survival, adhesion, and invasion of glioblastoma cell
lines. Br J Cancer. 89:2122–2132. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Short SC, Martindale C, Bourne S, Brand G,
Woodcock M and Johnston P: DNA repair after irradiation in glioma
cells and normal human astrocytes. Neuro Oncol. 9:404–411. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Hall JS, Iype R, Senra J, Taylor J,
Armenoult L, Oguejiofor K, Li Y, Stratford I, Stern PL, O’Connor
MJ, et al: Investigation of radiosensitivity gene signatures in
cancer cell lines. PLoS One. 9:pp. e863292014, View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Nilsson S, Carlsson J, Larsson B and
Ponten J: Survival of irradiated glia and glioma cells studied with
a new cloning technique. Int J Radiat Biol Relat Stud Phys Chem
Med. 37:267–279. 1980. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Deschavanne PJ, Fertil B, Malaise EP and
Lachet B: Radiosensitivity and repair of radiation damage in human
HF19 fibroblasts. Int J Radiat Biol Relat Stud Phys Chem Med.
38:167–177. 1980. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Carrie C, Muracciole X, Gomez F, Habrand
JL, Benhassel M, Mege M, Mahé M, Quetin P, Maire JP, Soum F, et al:
Conformal radiotherapy, reduced boost volume, hyperfractionated
radiotherapy, and online quality control in standard-risk
medulloblastoma without chemotherapy: Results of the French M-SFOP
98 protocol. Int J Radiat Oncol Biol Phys. 63:711–716. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Hall E and Giaccia A: Radiobiology for the
Radiologist. 7th edition. Lippincott, Williams & Wilkins;
Philadelphia, USA: 2012
|
|
36
|
Fernandez-Capetillo O, Lee A, Nussenzweig
M and Nussenzweig A: H2AX: The histone guardian of the genome. DNA
Repair (Amst). 3:959–967. 2004. View Article : Google Scholar
|
|
37
|
Westhoff MA, Kandenwein JA, Karl S,
Vellanki SH, Braun V, Eramo A, Antoniadis G, Debatin KM, Fulda S,
et al: The pyridinylfuranopyrimidine inhibitor, PI-103,
chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA
repair. Oncogene. 28:3586–3596. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Westhoff MA, Faham N, Marx D, Nonnenmacher
L, Jennewein C, Enzenmüller S, Gonzalez P, Fulda S and Debatin KM:
Sequential Dosing in Chemosensitization: Targeting the
PI3K/Akt/mTOR Pathway in Neuroblastoma. PLoS One. 8:pp. e831282013,
View Article : Google Scholar
|
|
39
|
Tsutsumi K, Tsuda M, Yazawa N, Nakamura H,
Ishihara S, Haga H, Yasuda M, Yamazaki R, Shirato H, Kawaguchi H,
et al: Increased motility and invasiveness in tumor cells that
survive 10Gy irradiation. Cell Struct Funct. 34:89–96. 2009.
View Article : Google Scholar
|
|
40
|
Jung JW, Hwang SY, Hwang JS, Oh ES, Park S
and Han IO: Ionising radiation induces changes associated with
epithelial-mesenchymal transdifferentiation and increased cell
motility of A549 lung epithelial cells. Eur J Cancer. 43:1214–1224.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Furnari FB, Fenton T, Bachoo RM, Mukasa A,
Stommel JM, Stegh A, Hahn WC, Ligon KL, Louis DN, Brennan C, et al:
Malignant astrocytic glioma: Genetics, biology, and paths to
treatment. Genes Dev. 21:2683–2710. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
CBTRUS. Central Brain Tumor Registry of
the US Statistical Report: 2009-2010 CBTRUS Statistical Report
Primary: Brain and Central Nervous System Tumors Diagnosed in the
United States in 2004-2006. Central Brain Tumor Registry of the US;
Hinsdale, IL: pp. 1–61. 2010
|
|
43
|
Robert M and Wastie M: Glioblastoma
multiforme: a rare manifestation of extensive liver and bone
metastases. Biomed Imaging Interv J. 4:pp. e32008, View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Beauchesne P: Extra-neural metastases of
malignant gliomas: Myth or reality? Cancers. 3:4612011. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Rao JS: Molecular mechanisms of glioma
invasiveness: The role of proteases. Nat Rev Cancer. 3:489–501.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Snuderl M, Fazlollahi L, Le LP, Nitta M,
Zhelyazkova BH, Davidson CJ, Akhavanfard S, Cahill DP, Aldape KD,
Betensky RA, et al: Mosaic amplification of multiple receptor
tyrosine kinase genes in glioblastoma. Cancer Cell. 20:810–817.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Ene CI and Fine HA: Many tumors in one: a
daunting therapeutic prospect. Cancer Cell. 20:695–697. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Wolburg H, Noell S, Fallier-Becker P, Mack
AF and Wolburg- Buchholz K: The disturbed blood-brain barrier in
human glioblastoma. Mol Aspects Med. 33:579–589. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Salphati L, Shahidi-Latham S, Quiason C,
Barck K, Nishimura M, Alicke B, Pang J, Carano RA, Olivero AG and
Phillips HS: Distribution of the phosphatidylinositol 3-kinase
inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2
intracranial glioblastoma models-assessment by matrix-assisted
laser desorption ionization imaging. Drug Metab Dispos.
42:1110–1116. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Drake CG, Pfalzner PM and Linell EA:
Intracavitary irradiation of malignant brain tumours. J Neurosurg.
20:428–434. 1963. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Peirce CB: The efficacy of radiation
therapy in the treatment of tumors of the brain and brain stem.
Clin Neurosurg. 10:195–211. 1964. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Walker MD, Strike TA and Sheline GE: An
analysis of dose- effect relationship in the radiotherapy of
malignant gliomas. Int J Radiat Oncol Biol Phys. 5:1725–1731. 1979.
View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Salazar OM, Philip Rubin MD, Feldstein ML
and Pizzutiello R: High dose radiation therapy in the treatment of
malignant gliomas: Final Report. Int J Radiat Oncol Biol Phys.
5:1733–1740. 1979. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Sheline GE: Radiotherapy for high grade
gliomas. Int J Radiat Oncol Biol Phys. 18:793–803. 1990. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Djuzenova CS, Guttler T, Berger S, Katzer
A and Flentje M: Differential response of human glioblastoma cell
lines to combined camptothecin and ionizing radiation treatment.
Cancer Biol Ther. 7:364–373. 2008. View Article : Google Scholar
|
|
56
|
Vellanki SH, Grabrucker A, Liebau S,
Proepper C, Eramo A, Braun V, Boeckers T, Debatin KM and Fulda S:
Small-molecule XIAP inhibitors enhance gamma-irradiation-induced
apoptosis in glioblastoma. Neoplasia. 11:743–752. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Berger R, Jennewein C, Marschall V, Karl
S, Cristofanon S, Wagner L, Vellanki SH, Hehlgans S, Rödel F,
Debatin KM, et al: NF-κB is required for Smac mimetic-mediated
sensitization of glioblastoma cells for γ-irradiation-induced
apoptosis. Mol Cancer Ther. 10:1867–1875. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Ma H, Rao L, Wang HL, Mao ZW, Lei RH, Yang
ZY, Qing H and Deng YL: Transcriptome analysis of glioma cells for
the dynamic response to γ-irradiation and dual regulation of
apoptosis genes: A new insight into radiotherapy for glioblastomas.
Cell Death Dis. 4:pp. e8952013, View Article : Google Scholar
|
|
59
|
Li N, Maly DJ, Chanthery YH, Sirkis DW,
Nakamura JL, Berger MS, James CD, Shokat KM, Weiss WA and Persson
AI: Radiotherapy followed by aurora kinase inhibition targets
tumor- propagating cells in human glioblastoma. Mol Cancer Ther.
14:419–428. 2015. View Article : Google Scholar
|
|
60
|
Setua S, Ouberai M, Piccirillo SG, Watts C
and Welland M: Cisplatin-tethered gold nanospheres for multimodal
chemoradiotherapy of glioblastoma. Nanoscale. 6:10865–10873. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Kuger S, Flentje M and Djuzenova CS:
Simultaneous perturbation of the MAPK and the PI3K/mTOR pathways
does not lead to increased radiosensitization. Radiat Oncol.
10:2142015. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Balbous A, Cortes U, Guilloteau K, Rivet
P, Pinel B, Duchesne M, Godet J, Boissonnade O, Wager M, Bensadoun
RJ, et al: A radio- sensitizing effect of RAD51 inhibition in
glioblastoma stem-like cells. BMC Cancer. 16:6042016. View Article : Google Scholar
|
|
63
|
Grunert M, Kassubek R, Danz B, Klemenz B,
Hasslacher S, Stroh S, Schneele L, Langhans J, Ströbele S, Barry
SE, et al: Radiation and Brain Tumors: An Overview. Crit Rev Oncog.
23:119–138. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Karagiannis GS, Pastoriza JM, Wang Y,
Harney AS, Entenberg D, Pignatelli J, Sharma VP, Xue EA, Cheng E,
D’Alfonso TM, et al: Neoadjuvant chemotherapy induces breast cancer
metastasis through a TMEM-mediated mechanism. Sci Transl Med. 9:pp.
eaan00262017, View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Giese A: Glioma invasion - pattern of
dissemination by mechanisms of invasion and surgical intervention,
pattern of gene expression and its regulatory control by
tumorsuppressor p53 and proto-oncogene ETS-1. Acta Neurochir Suppl.
88:153–162. 2003.
|
|
66
|
Hatzikirou H, Basanta D, Simon M, Schaller
K and Deutsch A: ‘Go or grow’: The key to the emergence of invasion
in tumour progression? . Math Med Biol. 29:49–65. 2012. View Article : Google Scholar
|
