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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2018 Volume 53 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Nogo‑B receptor in relevant carcinoma: Current achievements, challenges and aims (Review)

Yu-Kun Li, Yuan‑Jie Xie, Dai-Chao Wu, Shuang-Lian Long, Shengsong Tang, Zhong-Cheng Mo
Pages: 1827-1835
Published online on: 09 August 2018

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Article Open Access

Inhibition of atypical protein kinase C‑ι effectively reduces the malignancy of prostate cancer cells by downregulating the NF-κB signaling cascade

André H. Apostolatos, Wishrawana S. Ratnayake, Hla Win-Piazza, Christopher A. Apostolatos, Tracess Smalley, Loveleen Kang, Raoul Salup, Robert Hill, Mildred Acevedo-Duncan
Pages: 1836-1846
Published online on: 28 August 2018

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Article Open Access

Knockdown of pleiotrophin increases the risk of preeclampsia following vitrified-thawed embryo transfer

Shengxian Liu, Fang Wang, Gelin Liu
Pages: 1847-1856
Published online on: 28 August 2018

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Article Open Access

Gene regulatory network construction identified NFYA as a diffuse subtype-specific prognostic factor in gastric cancer

Bin Cao, Yu Zhao, Zheng Zhang, Hengcun Li, Jie Xing, Shuilong Guo, Xintao Qiu, Shutian Zhang, Li Min, Shengtao Zhu
Pages: 1857-1868
Published online on: 09 August 2018

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Article Open Access

COL1A1: A potential therapeutic target for colorectal cancer expressing wild-type or mutant KRAS

Zheying Zhang, Cheng Fang, Yongxia Wang, Jinghang Zhang, Jian Yu, Yongxi Zhang, Xianwei Wang, Jiateng Zhong
Pages: 1869-1880
Published online on: 22 August 2018

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Article Open Access

Inhibition of PI3K signalling increases the efficiency of radiotherapy in glioblastoma cells

Sebastian Hasslacher, Lukas Schneele, Sebastien Stroh, Julia Langhans, Katharina Zeiler, Patricia Kattner, Georg Karpel-Massler, Markus D. Siegelin, Matthias Schneider, Shaoxia Zhou, Michael Grunert, Marc-Eric Halatsch, Lisa Nonnenmacher, Klaus-Michael Debatin, Mike-Andrew Westhoff
Pages: 1881-1896
Published online on: 16 August 2018

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Article Open Access

DNA topoisomerase 1 and 2A function as oncogenes in liver cancer and may be direct targets of nitidine chloride

Li-Min Liu, Dan-Dan Xiong, Peng Lin, Hong Yang, Yi-Wu Dang, Gang Chen
Pages: 1897-1912
Published online on: 21 August 2018

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Article Open Access

Upregulation of liver kinase B1 predicts poor prognosis in hepatocellular carcinoma

Xiaolong Tan, Zhibin Liao, Huifang Liang, Xiaoping Chen, Bixiang Zhang, Liang Chu
Pages: 1913-1926
Published online on: 07 September 2018

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Article Open Access

lncRNA LINC00673 induces proliferation, metastasis and epithelial-mesenchymal transition in thyroid carcinoma via Kruppel-like factor 2

Erjie Xia, Adheesh Bhandari, Yanyan Shen, Xiaofen Zhou, Ouchen Wang
Pages: 1927-1938
Published online on: 14 August 2018

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Article Open Access

KIF14 promotes cell proliferation via activation of Akt and is directly targeted by miR-200c in colorectal cancer

Zao-Zao Wang, Jie Yang, Bei-Hai Jiang, Jia-Bo Di, Pin Gao, Lin Peng, Xiang-Qian Su
Pages: 1939-1952
Published online on: 29 August 2018

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Article Open Access

P2Y2R-mediated inflammasome activation is involved in tumor progression in breast cancer cells and in radiotherapy-resistant breast cancer

Hana Jin, Young Shin Ko, Hye Jung Kim
Pages: 1953-1966
Published online on: 04 September 2018

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Article Open Access

Human non‑small cell lung cancer cells can be sensitized to camptothecin by modulating autophagy

Yi-Han Chiu, Shih-Hsien Hsu, Hsiao-Wei Hsu, Kuo-Chin Huang, Wangta Liu, Chang-Yi Wu, Wei-Pang Huang, Jeff Yi‑Fu Chen, Bing-Hung Chen, Chien-Chih Chiu
Pages: 1967-1979
Published online on: 14 August 2018

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Article Open Access

ARHGEF7 promotes metastasis of colorectal adenocarcinoma by regulating the motility of cancer cells

Xiong Lei, Li Deng, Dongning Liu, Shijun Liao, Hua Dai, Jiaxi Li, Jun Rong, Zhiwen Wang, Guodong Huang, Cheng Tang, Chen Xu, Benping Xiao, Taiyuan Li
Pages: 1980-1996
Published online on: 22 August 2018

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Article Open Access

Distinct phenotypes and ‘bystander’ effects of senescent tumour cells induced by docetaxel or immunomodulatory cytokines

Olena Sapega, Romana Mikyšková, Jana Bieblová, Blanka Mrázková, Zdeněk Hodný, Milan Reiniš
Pages: 1997-2009
Published online on: 05 September 2018

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Article Open Access

Overexpression of SENP1 reduces the stemness capacity of osteosarcoma stem cells and increases their sensitivity to HSVtk/GCV Corrigendum in /10.3892/ijo.2019.4752

Fengting Liu, Lili Li, Yanxia Li, Xiaofang Ma, Xiyun Bian, Xiaozhi Liu, Guowen Wang, Dianying Zhang
Pages: 2010-2020
Published online on: 23 August 2018

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Article Open Access

CDCA3 mediates p21-dependent proliferation by regulating E2F1 expression in colorectal cancer

Wenwei Qian, Zhiyuan Zhang, Wen Peng, Jie Li, Qiou Gu, Dongjian Ji, Qingyuan Wang, Yue Zhang, Bing Ji, Sen Wang, Dongsheng Zhang, Yueming Sun
Pages: 2021-2033
Published online on: 23 August 2018

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Article Open Access

Preclinical investigation of folate receptor-targeted nanoparticles for photodynamic therapy of malignant pleural mesothelioma

Tatsuya Kato, Cheng S. Jin, Daiyoon Lee, Hideki Ujiie, Kosuke Fujino, Hsin-Pei Hu, Hironobu Wada, Licun Wu, Juan Chen, Rober A. Weersink, Hiromi Kanno, Yutaka Hatanaka, Kanako C. Hatanaka, Kichizo Kaga, Yoshiro Matsui, Yoshihiro Matsuno, Marc De Perrot, Brian C. Wilson, Gang Zheng, Kazuhiro Yasufuku
Pages: 2034-2046
Published online on: 07 September 2018

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Article Open Access

Dynamic influence of Rhein lysinate on HeLa cells

Jiang Liu, Yong-Zhan Zhen, Ju Cui, Gang Hu, Jie Wei, Rong Xu, Ping Tu, Ya-Jun Lin
Pages: 2047-2055
Published online on: 05 September 2018

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Article Open Access

Knockdown of anti-silencing function 1B histone chaperone induces cell apoptosis via repressing PI3K/Akt pathway in prostate cancer

Guangye Han, Xinjun Zhang, Pei Liu, Quanfeng Yu, Zeyu Li, Qinnan Yu, Xiaoxia Wei
Pages: 2056-2066
Published online on: 16 August 2018

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Article

The PDK1/c‑Jun pathway activated by TGF‑β induces EMT and promotes proliferation and invasion in human glioblastoma

Dingyuan Luo, Xinke Xu, Junliang Li, Cheng Chen, Wei Chen, Fangyu Wang, Yanping Xie, Fangcheng Li
Pages: 2067-2080
Published online on: 14 August 2018

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Article

Long non-coding RNA CASC2 inhibits breast cancer cell growth and metastasis through the regulation of the miR-96-5p/SYVN1 pathway

Zejun Gao, Hai Wang, Hangyu Li, Min Li, Jia Wang, Wenwen Zhang, Xiubin Liang, Dongming Su, Jinhai Tang
Pages: 2081-2090
Published online on: 13 August 2018

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Article

Anticancer effects of oridonin on colon cancer are mediated via BMP7/p38 MAPK/p53 signaling

Rong-Xing Liu, Yan Ma, Xue-Lian Hu, Wen-Yan Ren, Yun-Peng Liao, Han Wang, Jia-Hui Zhu, Ke Wu, Bai-Cheng He, Wen-Juan Sun
Pages: 2091-2101
Published online on: 16 August 2018

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Article

ZBTB7 evokes 5-fluorouracil resistance in colorectal cancer through the NF‑κB signaling pathway

Zexin Wang, Xilan Zhao, Wei Wang, Yishu Liu, Yanyan Li, Junyong Gao, Cancan Wang, Meiyu Zhou, Ruyan Liu, Guofa Xu, Qi Zhou
Pages: 2102-2110
Published online on: 10 August 2018

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Article

Membrane proteomics of cervical cancer cell lines reveal insights on the process of cervical carcinogenesis

Kalliopi I. Pappa, Polyxeni Christou, Amarildo Xholi, George Mermelekas, Georgia Kontostathi, Vasiliki Lygirou, Manousos Makridakis, Jerome Zoidakis, Nicholas P. Anagnou
Pages: 2111-2122
Published online on: 07 August 2018

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Article

Resveratrol promotes the sensitivity of small-cell lung cancer H446 cells to cisplatin by regulating intrinsic apoptosis

Wangping Li, Yun Shi, Ruixuan Wang, Lei Pan, Lijie Ma, Faguang Jin
Pages: 2123-2130
Published online on: 21 August 2018

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Article

Serum miR-30d as a novel biomarker for multiple myeloma and its antitumor role in U266 cells through the targeting of the MTDH/PI3K/Akt signaling pathway

Bingying Zhu, Hongmei Chen, Xiaofen Zhang, Yafang Pan, Rongrong Jing, Lei Shen, Xudong Wang, Shaoqing Ju, Chunjing Jin, Hui Cong
Pages: 2131-2144
Published online on: 21 August 2018

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Article

MicroRNA-1254 exerts oncogenic effects by directly targeting RASSF9 in human breast cancer

Bin Li, Peng Chen, Jialin Wang, Linxia Wang, Mingzhi Ren, Ruisan Zhang, Jianjun He
Pages: 2145-2156
Published online on: 21 August 2018

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Article

Tamoxifen inhibits the proliferation of non‑melanoma skin cancer cells by increasing intracellular calcium concentration

Go Hasegawa, Kotomi Akatsuka, Yuichi Nakashima, Yumiko Yokoe, Narumi Higo, Motoyuki Shimonaka
Pages: 2157-2166
Published online on: 31 August 2018

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Article

Uncovering the pharmacological response of novel sesquiterpene derivatives that differentially alter gene expression and modulate the cell cycle in cancer cells

Melpomeni G. Akrivou, Vera P. Demertzidou, Nikoleta F. Theodoroula, Fani M. Chatzopoulou, Konstantinos A. Kyritsis, Nikolaos Grigoriadis, Alexandros L. Zografos, Ioannis S. Vizirianakis
Pages: 2167-2179
Published online on: 03 September 2018

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Article

Silencing the expression of MTDH increases the radiation sensitivity of SKOV3 ovarian cancer cells and reduces their proliferation and metastasis

Jun Chen, Yan Jia, Zan-Hui Jia, Yu Zhu, Yue-Mei Jin
Pages: 2180-2190
Published online on: 28 August 2018

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Article

MicroRNA‑143 increases cell apoptosis in myelodysplastic syndrome through the Fas/FasL pathway both in vitro and in vivo

Jiaqi Cui, Chunmei Wei, Linli Deng, Xingyi Kuang, Zengtie Zhang, Chryso Pierides, Jianxiang Chi, Li Wang
Pages: 2191-2199
Published online on: 22 August 2018

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Article

hnRNPK modulates selective quality-control autophagy by downregulating the expression of HDAC6 in 293 cells

Zhipeng Li, Xiaohui Liu, Jie Ma, Tingting Zhang, Xuejuan Gao, Langxia Liu
Pages: 2200-2212
Published online on: 07 August 2018

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Article

Effects of 3-butenyl isothiocyanate on phenotypically different prostate cancer cells

M.j. Núñez-Iglesias, S. Novio, C. García-Santiago, M.e. Cartea, P. Soengas, P. Velasco, M. Freire-Garabal
Pages: 2213-2223
Published online on: 29 August 2018

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Article

ARHGEF4 predicts poor prognosis and promotes cell invasion by influencing ERK1/2 and GSK-3α/β signaling in pancreatic cancer

Keisuke Taniuchi, Mutsuo Furihata, Seiji Naganuma, Toshiji Saibara
Pages: 2224-2240
Published online on: 31 August 2018

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Article

miR-17-92 functions as an oncogene and modulates NF-κB signaling by targeting TRAF3 in MGC-803 human gastric cancer cells

Fei Liu, Li Cheng, Jingjing Xu, Feng Guo, Weichang Chen
Pages: 2241-2257
Published online on: 28 August 2018

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Article

β-catenin decreases acquired TRAIL resistance in non-small-cell lung cancer cells by regulating the redistribution of death receptors

Chengcheng You, Shimin Zhang, Yingming Sun, Shiyu Zhang, Guiliang Tang, Fang Tang, Xuefeng Liu, Yu Xiao, Junhong Zhang, Yan Gong, Conghua Xie
Pages: 2258-2268
Published online on: 21 August 2018

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Article

Rotundic acid enhances the impact of radiological toxicity on MCF-7 cells through the ATM/p53 pathway

Zhong-Feng Wang, Wen-Yi Sun, De-Hai Yu, Yan Zhao, Hong-Mei Xu, Yu-Fang He, Hai-Jun Li
Pages: 2269-2277
Published online on: 29 August 2018

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Article

Long non-coding RNA HOTTIP promotes renal cell carcinoma progression through the regulation of the miR-615/IGF-2 pathway

Qifei Wang, Guangzhen Wu, Zhiwei Zhang, Qizhen Tang, Wei Zheng, Xiaochi Chen, Feng Chen, Quanlin Li, Xiangyu Che
Pages: 2278-2288
Published online on: 23 August 2018

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Article

B7-H3 on circulating epithelial tumor cells correlates with the proliferation marker, Ki-67, and may be associated with the aggressiveness of tumors in breast cancer patients

Monika Pizon, Dorothea Sonja Schott, Ulrich Pachmann, Katharina Pachmann
Pages: 2289-2299
Published online on: 04 September 2018

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Article

Induction of apoptosis and G1 phase cell cycle arrest by Aster incisus in AGS gastric adenocarcinoma cells

Daniel Ngabire, Yeong-Ae Seong, Maheshkumar Prakash Patil, Irvine Niyonizigiye, Yong Bae Seo, Gun-Do Kim
Pages: 2300-2308
Published online on: 30 August 2018

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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