|
1
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Chen W, Zheng R, Baade PD, Zhang S, Zeng
H, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in China,
2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Brenner H, Kloor M and Pox CP: Colorectal
cancer. Lancet. 383:1490–1502. 2014. View Article : Google Scholar
|
|
4
|
Kobayashi H, Ueno H, Hashiguchi Y and
Mochizuki H: Distribution of lymph node metastasis is a prognostic
index in patients with stage III colon cancer. Surgery.
139:516–522. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Reddy GK: Prognostic significance of
increasing lymph node count in stage III colorectal cancer. Clin
Colorectal Cancer. 5:403–404. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Rosenberg R, Engel J, Bruns C, Heitland W,
Hermes N, Jauch KW, Kopp R, Pütterich E, Ruppert R, Schuster T, et
al: The prognostic value of lymph node ratio in a population-based
collective of colorectal cancer patients. Ann Surg. 251:1070–1078.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Valastyan S and Weinberg RA: Tumor
metastasis: Molecular insights and evolving paradigms. Cell.
147:275–292. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Hanahan D and Weinberg RA: Hallmarks of
cancer: The next generation. Cell. 144:646–674. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Koh CG, Manser E, Zhao ZS and Ng CP: Lim
L. Beta1PIX, the PAK-interacting exchange factor, requires
localization via a coiled-coil region to promote microvillus-like
structures and membrane ruffles. J Cell Sci. 114:4239–4251.
2001.PubMed/NCBI
|
|
10
|
Lee S, Eom M, Lee SJ, Kim S, Park H and
Park D: βPix-enhanced p38 Activation by
Cdc42/Rac/PAK/MKK3/6-mediated Pathway. J Biol Chem.
276:25066–25072. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Kuo JC, Han X, Hsiao CT, Yates JR III and
Waterman CM: Analysis of the myosin-II-responsive focal adhesion
proteome reveals a role for β-Pix in negative regulation of focal
adhesion maturation. Nat Cell Biol. 13:383–393. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Campa F, Machuy N, Klein A and Rudel T: A
new interaction between Abi-1 and betaPIX involved in
PDGF-activated actin cytoskeleton reorganisation. Cell Res.
16:759–770. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Heidary Arash E, Song KM, Song S, Shiban A
and Attisano L: Arhgef7 promotes activation of the Hippo pathway
core kinase Lats. EMBO J. 33:2997–3011. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Wang H, Han M, Whetsell W Jr, Wang J, Rich
J, Hallahan D and Han Z: Tax-interacting protein 1 coordinates the
spatiotemporal activation of Rho GTPases and regulates the
infiltrative growth of human glioblastoma. Oncogene. 33:1558–1569.
2014. View Article : Google Scholar :
|
|
15
|
Hsu YH, Lin WL, Hou YT, Pu YS, Shun CT,
Chen CL, Wu YY, Chen JY, Chen TH and Jou TS: Podocalyxin EBP50
ezrin molecular complex enhances the metastatic potential of renal
cell carcinoma through recruiting Rac1 guanine nucleotide exchange
factor ARHGEF7. Am J Pathol. 176:3050–3061. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Muñoz-Bellvis L, Fontanillo C,
González-González M, Garcia E, Iglesias M, Esteban C, Gutierrez ML,
Abad MM, Bengoechea O, De Las Rivas J, et al: Unique genetic
profile of sporadic colorectal cancer liver metastasis versus
primary tumors as defined by high- density single-nucleotide
polymorphism arrays. Mod Pathol. 25:590–601. 2012. View Article : Google Scholar
|
|
17
|
Zhang Y, Davis C, Shah S, Hughes D, Ryan
JC, Altomare D and Peña MM: IL-33 promotes growth and liver
metastasis of colorectal cancer in mice by remodeling the tumor
microenvironment and inducing angiogenesis. Mol Carcinog.
56:272–287. 2017. View Article : Google Scholar :
|
|
18
|
McShane LM, Altman DG, Sauerbrei W, Taube
SE, Gion M and Clark GM; Statistics Subcommittee of the NCI-EORTC
Working Group on Cancer Diagnostics: Reporting recommendations for
tumor marker prognostic studies (REMARK). J Natl Cancer Inst.
97:1180–1184. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-ΔΔC(T)) method. Methods. 25:402–408. 2001. View Article : Google Scholar
|
|
20
|
Lei X, Liang Y, Chen J, Xiao S, Lei J, Li
J, Duanmu J, Jiang Q, Liu D, Tang C, et al: Sorcin predicts poor
prognosis and promotes metastasis by facilitating
epithelial-mesenchymal transition in hepatocellular carcinoma. Sci
Rep. 7:100492017. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Liu Su, Chen SQ, Chen J, Chen J, He F,
Huang C, Wu D, Lin W, Huang LW, et al: A positive feedback loop
between mesenchymal-like cancer cells and macrophages is essential
to breast cancer metastasis. Cancer Cell. 25:605–620. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
García-Echeverría C, Pearson MA, Marti A,
Meyer T, Mestan J, Zimmermann J, Gao J, Brueggen J, Capraro HG,
Cozens R, et al: In vivo antitumor activity of NVP-AEW541-A novel,
potent, and selective inhibitor of the IGF-IR kinase. Cancer Cell.
5:231–239. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Yokoi K, Thaker PH, Yazici S, Rebhun RR,
Nam DH, He J, Kim SJ, Abbruzzese JL, Hamilton SR and Fidler IJ:
Dual inhibition of epidermal growth factor receptor and vascular
endothelial growth factor receptor phosphorylation by AEE788
reduces growth and metastasis of human colon carcinoma in an
orthotopic nude mouse model. Cancer Res. 65:3716–3725. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Insall RH and Machesky LM: Actin dynamics
at the leading edge: From simple machinery to complex networks. Dev
Cell. 17:310–322. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Reddy PN, Radu M, Xu K, Wood J, Harris CE,
Chernoff J and Williams DA: p21-activated kinase 2 regulates HSPC
cytoskeleton, migration, and homing via CDC42 activation and
interaction with β-Pix. Blood. 127:1967–1975. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
ten Klooster JP, Jaffer ZM, Chernoff J and
Hordijk PL: Targeting and activation of Rac1 are mediated by the
exchange factor beta-Pix. J Cell Biol. 172:759–769. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Guinney J, Dienstmann R, Wang X, de
Reyniès A, Schlicker A, Soneson C, Marisa L, Roepman P, Nyamundanda
G, Angelino P, et al: The consensus molecular subtypes of
colorectal cancer. Nat Med. 21:1350–1356. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Sahani DV, Bajwa MA, Andrabi Y, Bajpai S
and Cusack JC: Current status of imaging and emerging techniques to
evaluate liver metastases from colorectal carcinoma. Ann Surg.
259:861–872. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Yu HW, Chen YQ, Huang CM, Liu CY, Chiou A,
Wang YK, Tang MJ and Kuo JC: β-PIX controls intracellular
viscoelasticity to regulate lung cancer cell migration. J Cell Mol
Med. 19:934–947. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Pang B, Wu N, Guan R, Pang L, Li X, Li S,
Tang L, Guo Y, Chen J, Sun D, et al: Overexpression of RCC2
enhances cell motility and promotes tumor metastasis in lung
adenocarcinoma by inducing epithelial-mesenchymal transition. Clin
Cancer Res. 23:5598–5610. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Sanoff HK, Sargent DJ, Campbell ME, Morton
RF, Fuchs CS, Ramanathan RK, Williamson SK, Findlay BP, Pitot HC
and Goldberg RM: Five-year data and prognostic factor analysis of
oxaliplatin and irinotecan combinations for advanced colorectal
cancer. J Clin Oncol. 26:5721–5727. 2008. View Article : Google Scholar : PubMed/NCBI
|
