|
1
|
Lynch HT, Snyder CL, Shaw TG, Heinen CD
and Hitchins MP: Milestones of Lynch syndrome: 1895-2015. Nat Rev
Cancer. 15:181–194. 2015. View
Article : Google Scholar : PubMed/NCBI
|
|
2
|
Peltomäki P: Lynch syndrome genes. Fam
Cancer. 4:227–232. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Bonadona V, Bonaïti B, Olschwang S,
Grandjouan S, Huiart L, Longy M, Guimbaud R, Buecher B, Bignon YJ,
Caron O, et al: Cancer risks associated with germline mutations in
MLH1, MSH2, and MSH6 genes in Lynch syndrome. JAMA. 305:2304–2310.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Deng G, Bell I, Crawley S, Gum J, Terdiman
JP, Allen BA, Truta B, Sleisenger MH and Kim YS: BRAF mutation is
frequently present in sporadic colorectal cancer with methylated
hMLH1, but not in hereditary nonpolyposis colorectal cancer. Clin
Cancer Res. 10:191–195. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Gryfe R, Kim H, Hsieh ET, Aronson MD,
Holowaty EJ, Bull SB, Redston M and Gallinger S: Tumor
microsatellite instability and clinical outcome in young patients
with colorectal cancer. N Engl J Med. 342:69–77. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Jeong SY, Shin KH, Shin JH, Ku JL, Shin
YK, Park SY, Kim WH and Park JG: Microsatellite instability and
mutations in DNA mismatch repair genes in sporadic colorectal
cancers. Dis Colon Rectum. 46:1069–1077. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Ackermann A, Schrecker C, Bon D,
Friedrichs N, Bankov K, Wild P, Plotz G, Zeuzem S, Herrmann E,
Hansmann ML and Brieger A: Downregulation of SPTAN1 is related to
MLH1 deficiency and metastasis in colorectal cancer. PLoS One.
14:e02134112019. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Michel S, Benner A, Tariverdian M,
Wentzensen N, Hoefler P, Pommerencke T, Grabe N, von Knebel
Doeberitz M and Kloor M: High density of FOXP3-positive T cells
infiltrating colorectal cancers with microsatellite instability. Br
J Cancer. 99:1867–1873. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Kloor M, Huth C, Voigt AY, Benner A,
Schirmacher P, von Knebel Doeberitz M and Bläker H: Prevalence of
mismatch repair-deficient crypt foci in Lynch syndrome: A
pathological study. Lancet Oncol. 13:598–606. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Kelderman S, Schumacher TN and Haanen JB:
Acquired and intrinsic resistance in cancer immunotherapy. Mol
Oncol. 8:1132–1139. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Ribic CM, Sargent DJ, Moore MJ, Thibodeau
SN, French AJ, Goldberg RM, Hamilton SR, Laurent-Puig P, Gryfe R,
Shepherd LE, et al: Tumor microsatellite-instability status as a
predictor of benefit from fluorouracil-based adjuvant chemotherapy
for colon cancer. N Engl J Med. 349:247–257. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Mandal R, Samstein RM, Lee KW, Havel JJ,
Wang H, Krishna C, Sabio EY, Makarov V, Kuo F, Blecua P, et al:
Genetic diversity of tumors with mismatch repair deficiency
influences anti-PD-1 immunotherapy response. Science. 364:485–491.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Stepanenko AA and Dmitrenko VV: HEK293 in
cell biology and cancer research: Phenotype, karyotype,
tumorigenicity, and stress-induced genome-phenotype evolution.
Gene. 569:182–190. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Jacob S, Aguado M, Fallik D and Praz F:
The role of the DNA mismatch repair system in the cytotoxicity of
the topoisomerase inhibitors camptothecin and etoposide to human
colorectal cancer cells. Cancer Res. 61:6555–6562. 2001.PubMed/NCBI
|
|
15
|
DSMZ: Catalogue of human and animal cell
lines. 2012.
|
|
16
|
Dirks WG, Faehnrich S, Estella IA and
Drexler HG: Short tandem repeat DNA typing provides an
international reference standard for authentication of human cell
lines. ALTEX. 22:103–109. 2005.PubMed/NCBI
|
|
17
|
Hinrichsen I, Ackermann A, Düding T,
Graband A, Filmann N, Plotz G, Zeuzem S and Brieger A: Loss of MLH1
sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648. Mol
Carcinog. 56:1816–1824. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Hinrichsen I, Ernst BP, Nuber F, Passmann
S, Schäfer D, Steinke V, Friedrichs N, Plotz G, Zeuzem S and
Brieger A: Reduced migration of MLH1 deficient colon cancer cells
depends on SPTAN1. Mol Cancer. 13:112014. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Peng W, Tan S, Xu Y, Wang L, Qiu D, Cheng
C, Lin Y, Liu C, Li Z, Li Y, et al: LC-MS/MS metabolome analysis
detects the changes in the lipid metabolic profiles of dMMR and
pMMR cells. Oncol Rep. 40:1026–1034. 2018.PubMed/NCBI
|
|
20
|
Suraweera N, Duval A, Reperant M, Vaury C,
Furlan D, Leroy K, Seruca R, Iacopetta B and Hamelin R: Evaluation
of tumor microsatellite instability using five quasimonomorphic
mono-nucleotide repeats and pentaplex PCR. Gastroenterology.
123:1804–1811. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Brieger A, Plotz G, Zeuzem S and Trojan J:
Thymosin beta 4 expression and nuclear transport are regulated by
hMLH1. Biochem Biophys Res Commun. 364:731–736. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
23
|
Ackermann H: Bias-a program package for
biometrical analysis of samples. Computational Statistics Data
Analysis. 11:223–224. 1991. View Article : Google Scholar
|
|
24
|
Landi S, Moreno V, Gioia-Patricola L,
Guino E, Navarro M, de Oca J, Capella G and Canzian F; Bellvitge
Colorectal Cancer Study Group: Association of common polymorphisms
in inflam-matory genes interleukin (IL)6, IL8, tumor necrosis
factor alpha, NFKB1, and peroxisome proliferator-activated receptor
gamma with colorectal cancer. Cancer Res. 63:3560–3566.
2003.PubMed/NCBI
|
|
25
|
Gunter MJ, Canzian F, Landi S, Chanock SJ,
Sinha R and Rothman N: Inflammation-related gene polymorphisms and
colorectal adenoma. Cancer Epidemiol Biomarkers Prev. 15:1126–1131.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Mustapha MA, Shahpudin SN, Aziz AA and
Ankathil R: Risk modification of colorectal cancer susceptibility
by interleukin-8-251T>A polymorphism in Malaysians. World J
Gastroenterol. 18:2668–2673. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Walczak A, Przybylowska K, Dziki L, Sygut
A, Chojnacki C, Chojnacki J, Dziki A and Majsterek I: The lL-8 and
IL-13 gene polymorphisms in inflammatory bowel disease and
colorectal cancer. DNA Cell Biol. 31:1431–1438. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Bondurant KL, Lundgreen A, Herrick JS,
Kadlubar S, Wolff RK and Slattery ML: Interleukin genes and
associations with colon and rectal cancer risk and overall
survival. Int J Cancer. 132:905–915. 2013. View Article : Google Scholar
|
|
29
|
Wang N, Zhou R, Wang C, Guo X, Chen Z,
Yang S and Li Y: -251 T/A polymorphism of the interleukin-8 gene
and cancer risk: A HuGE review and meta-analysis based on 42
case-control studies. Mol Biol Rep. 39:2831–2841. 2012. View Article : Google Scholar
|
|
30
|
Gonzalez-Hormazabal P, Romero S, Musleh M,
Bustamante M, Stambuk J, Pisano R, Lanzarini E, Chiong H, Rojas J,
Castro VG, et al: IL-8-251T>A (rs4073) polymorphism is
associ-ated with prognosis in gastric cancer patients. Anticancer
Res. 38:5703–5708. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Lurje G, Zhang W, Schultheis AM, Yang D,
Groshen S, Hendifar AE, Husain H, Gordon MA, Nagashima F, Chang HM
and Lenz HJ: Polymorphisms in VEGF and IL-8 predict tumor
recurrence in stage III colon cancer. Ann Oncol. 19:1734–1741.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Cacev T, Radosevic S, Krizanac S and
Kapitanović S: Influence of interleukin-8 and interleukin-10 on
sporadic colon cancer development and progression. Carcinogenesis.
29:1572–1580. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Wilkening S, Tavelin B, Canzian F, Enquist
K, Palmqvist R, Altieri A, Hallmans G, Hemminki K, Lenner P and
Försti A: Interleukin promoter polymorphisms and prognosis in
colorectal cancer. Carcinogenesis. 29:1202–1206. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Ali H, Bitar MS, Al Madhoun A, Marafie M
and Al-Mulla F: Functionally-focused algorithmic analysis of high
resolution microarray-CGH genomic landscapes demonstrates
comparable genomic copy number aberrations in MSI and MSS sporadic
colorectal cancer. PLoS One. 12:e01716902017. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Lee YS, Choi I, Ning Y, Kim NY,
Khatchadourian V, Yang D, Chung HK, Choi D, LaBonte MJ, Ladner RD,
et al: Interleukin-8 and its receptor CXCR2 in the tumour
microenvironment promote colon cancer growth, progression and
metastasis. Br J Cancer. 106:1833–1841. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
McClelland MR, Carskadon SL, Zhao L, White
ES, Beer DG, Orringer MB, Pickens A, Chang AC and Arenberg DA:
Diversity of the angiogenic phenotype in non-small cell lung
cancer. Am J Respir Cell Mol Biol. 36:343–350. 2007. View Article : Google Scholar
|
|
37
|
Waugh DJ and Wilson C: The interleukin-8
pathway in cancer. Clin Cancer Res. 14:6735–6741. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Thuringer D, Berthenet K, Cronier L,
Solary E and Garrido C: Primary tumor- and metastasis-derived colon
cancer cells differently modulate connexin expression and function
in human capillary endothelial cells. Oncotarget. 6:28800–28815.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Brew R, Erikson JS, West DC, Kinsella AR,
Slavin J and Christmas SE: Interleukin-8 as an autocrine growth
factor for human colon carcinoma cells in vitro. Cytokine.
12:78–85. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Addison CL, Daniel TO, Burdick MD, Liu H,
Ehlert JE, Xue YY, Buechi L, Walz A, Richmond A and Strieter RM:
The CXC chemokine receptor 2, CXCR2, is the putative receptor for
ELR+ CXC chemokine-induced angiogenic activity. J Immunol.
165:5269–5277. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Heidemann J, Ogawa H, Dwinell MB, Rafiee
P, Maaser C, Gockel HR, Otterson MF, Ota DM, Lugering N, Domschke W
and Binion DG: Angiogenic effects of interleukin 8 (CXCL8) in human
intestinal microvascular endothelial cells are mediated by CXCR2. J
Biol Chem. 278:8508–8515. 2003. View Article : Google Scholar
|
|
42
|
Hess C, Means TK, Autissier P, Woodberry
T, Altfeld M, Addo MM, Frahm N, Brander C, Walker BD and Luster AD:
IL-8 responsiveness defines a subset of CD8 T cells poised to kill.
Blood. 104:3463–3471. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Taub DD, Anver M, Oppenheim JJ, Longo DL
and Murphy WJ: T lymphocyte recruitment by interleukin-8 (IL-8).
IL-8-induced degranulation of neutrophils releases potent
chemoattractants for human T lymphocytes both in vitro and in vivo.
J Clin Invest. 97:1931–1941. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Kelly CP, Keates S, Siegenberg D, Linevsky
JK, Pothoulakis C and Brady HR: IL-8 secretion and neutrophil
activation by HT-29 colonic epithelial cells. Am J Physiol.
267:G991–G997. 1994.PubMed/NCBI
|
|
45
|
Godaly G, Hang L, Frendèus B and Svanborg
C: Transepithelial neutrophil migration is CXCR1 dependent in vitro
and is defective in IL-8 receptor knockout mice. J Immunol.
165:5287–5294. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
David JM, Dominguez C, Hamilton DH and
Palena C: The IL-8/IL-8R Axis: A double agent in tumor immune
resistance. Vaccines (Basel). 4:pii: E22. 2016.
|
|
47
|
Buckowitz A, Knaebel HP, Benner A, Bläker
H, Gebert J, Kienle P, von Knebel Doeberitz M and Kloor M:
Microsatellite instability in colorectal cancer is associated with
local lympho-cyte infiltration and low frequency of distant
metastases. Br J Cancer. 92:1746–1753. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Kloor M and von Knebel Doeberitz M: The
immune biology of microsatellite-unstable cancer. Trends Cancer.
2:121–133. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Aarts CEM and Kuijpers TW: Neutrophils as
myeloid-derived suppressor cells. Eur J Clin Invest. 48 (Suppl 2):
e129892018. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Alfaro C, Teijeira A, Oñate C, Pérez G,
Sanmamed MF, Andueza MP, Alignani D, Labiano S, Azpilikueta A,
Rodriguez-Paulete A, et al: Tumor-produced Interleukin-8 attracts
human myeloid-derived suppressor cells and elicits extrusion of
neutrophil extracellular traps (NETs). Clin Cancer Res.
22:3924–3936. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Brinkmann V, Reichard U, Goosmann C,
Fauler B, Uhlemann Y, Weiss DS, Weinrauch Y and Zychlinsky A:
Neutrophil extracellular traps kill bacteria. Science.
303:1532–1535. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Gonzalez-Aparicio M and Alfaro C:
Influence of Interleukin-8 and Neutrophil Extracellular Trap (NET)
formation in the tumor microenvironment: Is there a pathogenic
role? J Immunol Res. 2019:62521382019. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Najmeh S, Cools-Lartigue J, Rayes RF,
Gowing S, Vourtzoumis P, Bourdeau F, Giannias B, Berube J, Rousseau
S, Ferri LE and Spicer JD: Neutrophil extracellular traps sequester
circulating tumor cells via β1-integrin mediated interactions. Int
J Cancer. 140:2321–2330. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Alfaro C, Sanmamed MF, Rodriguez-Ruiz ME,
Teijeira Á, Oñate C, González Á, Ponz M, Schalper KA, Pérez-Gracia
JL and Melero I: Interleukin-8 in cancer pathogenesis, treatment
and follow-up. Cancer Treat Rev. 60:24–31. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Germini DE, Franco MIF, Fonseca FLA, de
Sousa Gehrke F, da Costa Aguiar Alves Reis B, Cardili L, Oshima
CTF, Theodoro TR and Waisberg J: Association of expression of
inflammatory response genes and DNA repair genes in colorectal
carcinoma. Tumour Biol. 42:10104283198430422019.PubMed/NCBI
|
|
56
|
Setrerrahmane S and Xu H: Tumor-related
interleukins: Old validated targets for new anti-cancer drug
development. Mol Cancer. 16:1532017. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Darbonne WC, Rice GC, Mohler MA, Apple T,
Hébert CA, Valente AJ and Baker JB: Red blood cells are a sink for
interleukin 8, a leukocyte chemotaxin. J Clin Invest. 88:1362–1369.
1991. View Article : Google Scholar : PubMed/NCBI
|
