|
1
|
Wang X, Lu Z, Gomez A, Hon GC, Yue Y, Han
D, Fu Y, Parisien M, Dai Q, Jia G, et al:
N6-methyladenosine-dependent regulation of messenger RNA stability.
Nature. 505:117–120. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Bartosovic M, Molares HC, Gregorova P,
Hrossova D, Kudla G and Vanacova S: N6-methyladenosine demethylase
FTO targets pre-mRNAs and regulates alternative splicing and 3′-end
processing. Nucleic Acids Res. 45:11356–11370. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Meyer KD, Patil DP, Zhou J, Zinoviev A,
Skabkin MA, Elemento O, Pestova TV, Qian SB and Jaffrey SR: 5′ UTR
m(6)A promotes cap-independent translation. Cell. 163:999–1010.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Liu N, Dai Q, Zheng G, He C, Parisien M
and Pan T: N(6)-methyladenosine-dependent RNA structural switches
regulate RNA-protein interactions. Nature. 518:560–564. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Roundtree IA, Evans ME, Pan T and He C:
Dynamic RNA modifications in gene expression regulation. Cell.
169:1187–1200. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Natchiar SK, Myasnikov AG, Kratzat H,
Hazemann I and Klaholz BP: Visualization of chemical modifications
in the human 80S ribosome structure. Nature. 551:472–477. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Sergiev PV, Aleksashin NA, Chugunova AA,
Polikanov YS and Dontsova OA: Structural and evolutionary insights
into ribosomal RNA methylation. Nat Chem Biol. 14:226–235. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Ma H, Wang X, Cai J, Dai Q, Natchiar SK,
Lv R, Chen K, Lu Z, Chen H, Shi YG, et al: N(6-)Methyladenosine
methyltransferase ZCCHC4 mediates ribosomal RNA methylation. Nat
Chem Biol. 15:88–94. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Pinto R, Vagbo CB, Jakobsson ME, Kim Y,
Baltissen MP, O'Donohue MF, Guzmán UH, Małecki JM, Wu J, Kirpekar
F, et al: The human methyltransferase ZCCHC4 catalyses
N6-methyladenosine modification of 28S ribosomal RNA. Nucleic Acids
Res. 48:830–846. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
van Tran N, Ernst FGM, Hawley BR, Zorbas
C, Ulryck N, Hackert P, Bohnsack KE, Bohnsack MT, Jaffrey SR,
Graille M and Lafontaine DLJ: The human 18S rRNA m6A
methyltransferase METTL5 is stabilized by TRMT112. Nucleic Acids
Res. 47:7719–7733. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Rong B, Zhang Q, Wan J, Xing S, Dai R, Li
Y, Cai J, Xie J, Song Y, Chen J, et al: Ribosome 18S m(6)A
methyltransferase METTL5 promotes translation initiation and breast
cancer cell growth. Cell Rep. 33:1085442020. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Ignatova VV, Stolz P, Kaiser S, Gustafsson
TH, Lastres PR, Sanz-Moreno A, Cho YL, Amarie OV, Aguilar-Pimentel
A, Klein-Rodewald T, et al: The rRNA m(6)A methyltransferase METTL5
is involved in pluripotency and developmental programs. Genes Dev.
34:715–729. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Wang L, Liang Y, Lin R, Xiong Q, Yu P, Ma
J, Cheng M, Han H, Wang X, Wang G, et al: Mettl5 mediated 18S rRNA
N6-methyladenosine (m6A) modification controls stem cell fate
determination and neural function. Genes & Diseases. 9:268–274.
2022. View Article : Google Scholar
|
|
14
|
Xing M, Liu Q, Mao C, Zeng H, Zhang X,
Zhao S, Chen L, Liu M, Shen B, Guo X, et al: The 18S rRNA m(6) A
methyltransferase METTL5 promotes mouse embryonic stem cell
differentiation. EMBO Rep. 21:e498632020. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Leismann J, Spagnuolo M, Pradhan M,
Wacheul L, Vu MA, Musheev M, Mier P, Andrade-Navarro MA, Graille M,
Niehrs C, et al: The 18S ribosomal RNA m(6) A methyltransferase
Mettl5 is required for normal walking behavior in Drosophila. EMBO
Rep. 21:e494432020. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Yoshida GJ: Emerging roles of Myc in stem
cell biology and novel tumor therapies. J Exp Clin Cancer Res.
37:1732018. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
AlSultan D, Kavanagh E, O'Grady S, Eustace
AJ, Castell A, Larsson LG, Crown J, Madden SF and Duffy MJ: The
novel low molecular weight MYC antagonist MYCMI-6 inhibits
proliferation and induces apoptosis in breast cancer cells. Invest
New Drugs. 39:587–594. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Destefanis F, Manara V and Bellosta P: Myc
as a regulator of ribosome biogenesis and cell competition: A link
to cancer. Int J Mol Sci. 21:40372020. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Wu H, Li F and Zhu R: miR-338-5p inhibits
cell growth and migration via inhibition of the METTL3/m6A/c-Myc
pathway in lung cancer. Acta Biochim Biophys Sin (Shanghai).
53:304–316. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Dang CV: MYC on the path to cancer. Cell.
149:22–35. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Shan H, Cao Y, Xiao X, Liu M and Wu Y, Zhu
Q, Xu H, Lei H, Yao Z and Wu Y: YL064 activates
proteasomal-dependent degradation of c-Myc and synergistically
enhances the anti-tumor activity of ABT-199 in diffuse large B cell
lymphoma. Signal Transduct Target Ther. 5:1162020. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Yang G, Xiong G, Feng M, Zhao F, Qiu J,
Liu Y, Cao Z, Wang H, Yang J, You L, et al: OLR1 promotes
pancreatic cancer metastasis via increased c-Myc expression and
transcription of HMGA2. Mol Cancer Res. 18:685–697. 2020.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Zhong Y, Yang L, Xiong F, He Y, Tang Y,
Shi L, Fan S, Li Z, Zhang S, Gong Z, et al: Long non-coding RNA
AFAP1-AS1 accelerates lung cancer cells migration and invasion by
interacting with SNIP1 to upregulate c-Myc. Signal Transduct Target
Ther. 6:2402021. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Shams R, Aghdaei HA, Behmanesh A, Sadeghi
A, Zali M, Salari S and Padrón JM: MicroRNAs targeting MYC
expression: Trace of hope for pancreatic cancer therapy. A
systematic review. Cancer Manag Res. 12:2393–2404. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Hessmann E, Schneider G, Ellenrieder V and
Siveke JT: MYC in pancreatic cancer: Novel mechanistic insights and
their translation into therapeutic strategies. Oncogene.
35:1609–1618. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Wang XS, He JR, Yu S and Yu J:
Methyltransferase-like 3 promotes the proliferation of acute
myeloid leukemia cells by regulating N6-methyladenosine Levels of
MYC. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 40:308–314. 2018.(In
Chinese). PubMed/NCBI
|
|
27
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Chen H, Liu Q, Yu D, Natchiar K, Zhou C,
Hsu CH, Hsu PH, Zhang X, Klaholz B, Gregory RI, et al: METTL5, an
18S rRNA-specific m6A methyltransferase, modulates expression of
stress response genes. bioRxiv. doi: 10.1101/2020.04.27.064162.
|
|
29
|
Lin S, Choe J, Du P, Triboulet R and
Gregory RI: The m(6)A methyltransferase METTL3 promotes translation
in human cancer cells. Mol Cell. 62:335–345. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Wilson C, Chen PJ, Miao Z and Liu DR:
Programmable m(6)A modification of cellular RNAs with a
Cas13-directed methyltransferase. Nat Biotechnol. 38:1431–1440.
2020. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Konermann S, Lotfy P, Brideau NJ, Oki J,
Shokhirev MN and Hsu PD: Transcriptome engineering with
RNA-targeting type VI-D CRISPR effectors. Cell. 173:665–676, e614.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Li S, Li X, Xue W, Zhang L, Yang LZ, Cao
SM, Lei YN, Liu CX, Guo SK, Shan L, et al: Screening for functional
circular RNAs using the CRISPR-Cas13 system. Nat Methods. 18:51–59.
2021. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Liger D, Mora L, Lazar N, Figaro S, Henri
J, Scrima N, Buckingham RH, van Tilbeurgh H, Heurgué-Hamard V and
Graille M: Mechanism of activation of methyltransferases involved
in translation by the Trm112 ‘hub’ protein. Nucleic Acids Res.
44:14822016. View Article : Google Scholar : PubMed/NCBI
|
