|
1
|
Hanif F, Muzaffar K, Perveen K, Malhi SM
and Simjee ShU: Glioblastoma multiforme: A review of its
epidemiology and pathogenesis through clinical presentation and
treatment. Asian Pac J Cancer Prev. 18:3–9. 2017.PubMed/NCBI
|
|
2
|
Strom QT, Gittleman H, Xu J, Kromer C,
Wolinsky Y, Kruchko C and Barnholtz-Sloan JS: CBTRUS statistical
report: Primary brain and other central nervous system tumors
diagnosed in the United States in 2009-2013. Neuro Oncol. 18(Suppl
5): v1–v75. 2016. View Article : Google Scholar
|
|
3
|
Louis DN, Ohgaki H, Wiestler OD, Cavenee
WK, Burger PC, Jouvet A, Scheithauer BW and Kleihues P: The 2007
WHO classification of tumours of the central nervous system. Acta
Neuropathol. 114:97–109. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Parsons DW, Jones S, Zhang X, Lin JC,
Leary RJ, Angenendt P, Mankoo P, Carter H, Siu IM, Gallia GL, et
al: An integrated genomic analysis of human glioblastoma
multiforme. Science. 321:1807–1812. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Ohgaki H, Dessen P, Jourde B, Horstmann S,
Nishikawa T, Di Patre PL, Burkhard C, Schüler D, Probst-Hensch NM,
Maiorka PC, et al: Genetic pathways to glioblastoma: A
population-based study. Cancer Res. 64:6892–6899. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Tykocki T and Eltayeb M: Ten-year survival
in glioblastoma. A systematic review J Clin Neurosci. 54:7–13.
2018. View Article : Google Scholar
|
|
7
|
Sathornsumetee S and Rich JN: Designer
therapies for glioblastoma multiforme. Ann N Y Acad Sci.
1142:108–132. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Witthayanuwat S, Pesee M, Supaadirek C,
Supakalin N, Thamronganantasakul K and Krusun S: Survival analysis
of glioblastoma multiforme. Asian Pac J Cancer Prev. 19:2613–2617.
2018.PubMed/NCBI
|
|
9
|
Preusser M, de Ribaupierre S, Wöhrer A,
Erridge SC, Hegi M, Weller M and Stupp R: Current concepts and
management of glioblastoma. Ann Neurol. 70:9–21. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Anjum K, Shagufta BI, Abbas SQ, Patel S,
Khan I, Shah SA, Akhter N and Hassan SS: Current status and future
therapeutic perspectives of glioblastoma multiforme (GBM) therapy:
A review. Biomed Pharmacother. 92:681–689. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Stupp R, Hegi ME, Gilbert MR and
Chakravarti A: Chemoradiotherapy in malignant glioma: Standard of
care and future directions. J ClinOncol. 25:4127–4136. 2007.
View Article : Google Scholar
|
|
12
|
Carson KA, Grossman SA, Fisher JD and Shaw
EG: Prognostic factors for survival in adult patients with
recurrent glioma enrolled onto the new approaches to brain tumor
therapy CNS consortium phase I and II clinical trials. J Clin
Oncol. 25:2601–2606. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Abe T, Mori T, Wakabayashi Y, Nakagawa M,
Cole SP, Koike K, Kuwano M and Hori S: Expression of multidrug
resistance protein gene in patients with glioma after chemotherapy.
J Neurooncol. 40:11–18. 1998. View Article : Google Scholar
|
|
14
|
Wang JB, Pan HX and Tang GL: Production of
doramectin by rational engineering of the avermectin biosynthetic
pathway. Bioorg Med Chem Lett. 21:3320–3323. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Murayama N, Shibata K and Nagata M:
Efficacy of weekly oral doramectin treatment in canine demodicosis.
Vet Rec. 167:63–64. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Taylor LF and Hodge A: Impact of a single
treatment of injectable doramectin on weight gain post weaning in
beef heifers and steers in central Queensland, Australia. Aust Vet
J. 97:185–190. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Gao A, Wang X, Xiang W, Liang H, Gao J and
Yan Y: Reversal of P-glycoprotein-mediated multidrug resistance in
vitro by doramectin and nemadectin. J Pharm Pharmacol. 61:393–399.
2010. View Article : Google Scholar
|
|
18
|
Kramer L, Crosara S, Gnudi G, Genchi M,
Mangia C, Viglietti A and Quintavalla C: Wolbachia, doxycycline and
macrocyclic lactones: New prospects in the treatment of canine
heartworm disease. Vet Parasitol. 254:95–97. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Ballweber LR and Baeten LA: Use of
macrocyclic lactones in cattle in the USA. Curr Pharm Biotechnol.
13:1061–1169. 2012. View Article : Google Scholar
|
|
20
|
Melotti A, Mas C, Kuciak M, Lorente-Trigos
A, Borges I and Ruiz i Altaba A: The river blindness drug
ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway
responses in human cancer. EMBO Mol Med. 6:1263–1278. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Song D, Liang H, Qu B, Li YJ, Liu JJ,
Zhang YN, Li L, Hu L, Zhang XT, Zhang X and Gao A: Ivermectin
inhibits the growth of glioma cells by inducing cell cycle arrest
and apoptosis in vitro and in vivo. J Cell Biochem. 120:622–633.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Zhang Y, Luo M, Xu W, Yang M, Wang B, Gao
J, Li Y and Tao L: Avermectin confers its cytotoxic effects by
inducing DNA damage and mitochondria-associated apoptosis. J Agric
Food Chemm. 64:6895–6902. 2016. View Article : Google Scholar
|
|
23
|
Drinyaev VA, Mosin VA, Kruglyak EB, Novik
TS, Sterlina TS, Ermakova NV, Kublik LN, Levitman MKh,
Shaposhnikova VV and Korystov YN: Antitumor effect of avermectins.
Eur J Pharmacol. 501:19–23. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Williams JC, Loyacano AF, DeRosa A, Gurie
J, Clymer BC and Guerino F: Comparison of persistent anthelmintic
efficacy of topical formulations of doramectin, ivermectin,
eprinomectin and moxidectin against naturally acquired nematode
infections of beef calves. Vet Parasitol. 85:277–288. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Rozali EN, Hato SV, Robinson BW, Lake RA
and Lesterhuis WJ: Programmed death ligand 2 in cancer-induced
immune suppression. Clin Dev Immunol. 2012:6563402012. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Hu J, Liu X, Hughes D, Esteva FJ, Liu B,
Chandra J and Li S: Herceptin conjugates linked by EDC boost direct
tumor cell death via programmed tumor cell necrosis. PLoS One.
6:e232702011. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Nordmann N, Hubbard M, Nordmann T,
Sperduto PW, Clark HB and Hunt MA: Effect of gamma knife
radiosurgery and programmed cell death 1 receptor antagonists on
metastatic melanoma. Cureus. 9:e19432017.
|
|
28
|
Speidel D: Transcription-independent p53
apoptosis: An alternative route to death. Trends Cell Biol.
20:14–24. 2010. View Article : Google Scholar
|
|
29
|
Klionsky DJ, Abeliovich H, Agostinis P,
Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA,
Ballabio A, et al: Guidelines for the use and interpretation of
assays for monitoring autophagy in higher eukaryotes. Autophagy.
4:151–175. 2010. View Article : Google Scholar
|
|
30
|
Kim KH and Lee MS: Autophagy-a key player
in cellular and body metabolism. Nat Rev Endocrinol. 10:322–337.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Liao Y, Duan B, Zhang Y, Zhang X and Xia
B: Excessive ER-phagy mediated by the autophagy receptor FAM134B
results in ER stress, the unfolded protein response, and cell death
in HeLa cells. J Biol Chem. 294:20009–20023. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Kim TW, Cheon C and Ko SG: SH003 activates
autophagic cell death by activating ATF4 and inhibiting G9a under
hypoxia in gastric cancer cells. Cell Death Dis. 11:7172020.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Klionsky DJ, Cuervo AM and Seglen PO:
Methods for monitoring autophagy from yeast to human. Autophagy.
3:181–206. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Wang J, Qi Q, Zhou W, Feng Z, Huang B,
Chen A, Zhang D, Li W, Zhang Q, Jiang Z, et al: Inhibition of
glioma growth by flavokawain B is mediated through endoplasmic
reticulum stress induced autophagy. Autophagy. 14:2007–2022. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Howarth A, Madureira PA, Lockwood G,
Storer LC, Grundy R, Rahman R, Pilkington GJ and Hill R: Modulating
autophagy as a therapeutic strategy for the treatment of paediatric
high-grade glioma. Brain Pathol. 29:707–725. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Liao Y, Smyth GK and Shi W: featureCounts:
An efficient general purpose program for assigning sequence reads
to genomic features. Bioinformatics. 30:923–930. 2014. View Article : Google Scholar
|
|
37
|
Maag JL: gganatogram: An R package for
modular visualisation of anatograms and tissues based on ggplot2.
F1000Res. 7:15762018. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Sturn A, Quackenbush J and Trajanoski Z:
Genesis: Cluster analysis of microarray data. Bioinformatics.
18:207–208. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Yu G, Wang LG, Han Y and He QY:
ClusterProfiler: An R package for comparing biological themes among
gene clusters. OMICS. 16:284–287. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Tanida I, Ueno T and Kominami E: LC3 and
autophagy. Methods Mol Biol. 445:77–88. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Onorati AV, Dyczynski M, Ojha R and
Amaravadi RK: Targeting autophagy in cancer. Cancer. 124:3307–3318.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Tanida I, Ueno T and Kominami E: LC3
conjugation system in mammalian autophagy. Int J Biochem Cell Biol.
36:2503–2518. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Mizushima N, Yoshimori T and Ohsumi Y: The
role of Atg proteins in autophagosome formation. Annu Rev Cell Dev
Biol. 27:107–132. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Gallardo F, Mariamé B, Gence R and
Tilkin-Mariamé AF: Macrocyclic lactones inhibit nasopharyngeal
carcinoma cells proliferation through PAK1 inhibition and reduce in
vivo tumor growth. Drug Des Devel Ther. 12:2805–2814. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Markowska A, Kaysiewicz J, Markowska J and
Huczyński A: Doxycycline, salinomycin, monensin and ivermectin
repositioned as cancer drugs. Bioorg Med Chem Lett. 29:1549–1554.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Juarez M, Schcolnik-Cabrera A and
Duenas-Gonzalez A: The multitargeted drug ivermectin: From an
antiparasitic agent to a repositioned cancer drug. Am J Cancer Res.
8:317–331. 2018.PubMed/NCBI
|
|
47
|
Zhang X, Zhang G, Zhai W, Zhao Z, Wang S
and Yi J: Inhibition of TMEM16A Ca2+-activated Cl-channels by
avermectins is essential for their anticancer effects. Pharmacol
Res. 156:1047632020. View Article : Google Scholar
|
|
48
|
Liu J, Liang H, Chen C, Wang X, Qu F, Wang
H, Yang K, Wang Q, Zhao N, Meng J and Gao A: Ivermectin induces
autophagy-mediated cell death through the AKT/mTOR signaling
pathway in glioma cells. Biosci Rep. 39:BSR201924892019. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Sheele JM, Ford LR, Tse A, Chidester B,
Byers PA and Sonenshine DE: The use of ivermectin to kill
ixodesscapularis ticks feeding on humans. Wilderness Environ Med.
25:29–34. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Klionsky DJ, Abdalla FC, Abeliovich H,
Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M,
Agostinis P, Aguirre-Ghiso JA, et al: Guidelines for the use and
interpretation of assays for monitoring autophagy. Autophagy.
8:445–544. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Xin P, Xu W, Zhu X, Li C, Zheng Y, Zheng
T, Cheng W and Peng Q: Protective autophagy or autophagic death:
Effects of BEZ235 on chronic myelogenous leukemia. Cancer Manag
Res. 11:7933–7951. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Pyo JO, Yoo SM, Ahn HH, Nah J, Hong SH,
Kam TI, Jung S and Jung YK: Overexpression of Atg5 in mice
activates autophagy and extends lifespan. Nat Commun. 4:23002013.
View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Levy JM, Towers CG and Thorburn A:
Targeting autophagy in cancer. Nat Rev Cancer. 17:528–542. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Baehrecke EH: Autophagy: Dual roles in
life and death? Nature Rev Mol Cell Biol. 6:505–510. 2005.
View Article : Google Scholar
|
|
55
|
Guo H, He Y, Bu C and Peng Z: Antitumor
and apoptotic effects of 5-methoxypsoralen in U87MG human glioma
cells and its effect on cell cycle, autophagy and PI3K/Akt
signaling pathway. Arch Med Sci. 15:1530–1538. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Mauthe M, Orhon I, Rocchi C, Zhou XD, Luhr
M, Hijlkema KJ, Coppes RP, Engedal N, Mari M and Reggiori F:
Chloroquine inhibits autophagic flux by decreasing
autophagosome-lysosome fusion. Autophagy. 14:1435–1455. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Lalaoui N, Lindqvist LM, Sandow JJ and
Ekert PG: The molecular relationships between apoptosis, autophagy
and necroptosis. Semin Cell Dev Biol. 39:63–69. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Maiuri MC, Zalckvar E, Kimchi A and
Kroemer G: Self-eating and self-killing: Crosstalk between
autophagy and apoptosis. Nat Rev Mol Cell Biol. 8:741–752. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
59
|
McCoy F, Hurwitz J, McTavish N, Paul I,
Barnes C, O'Hagan B, Odrzywol K, Murray J, Longley D, McKerr G and
Fennell DA: Obatoclax induces Atg7-dependent autophagy independent
of beclin-1 and BAX/BAK. Cell Death Dis. 1:e1082010. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Lin JZ, Wang WW, Hu TT, Zhu GY, Li LN,
Zhang CY, Xu Z, Yu HB, Wu HF and Zhu JG: FOXM1 contributes to
docetaxel resistance in castration-resistant prostate cancer by
inducing AMPK/mTOR-mediated autophagy. Cancer Lett. 469:481–489.
2020. View Article : Google Scholar
|
|
61
|
Liu JZ, Hu YL, Feng Y, Guo YB, Liu YF,
Yang JL, Mao QS and Xue WJ: Rafoxanide promotes apoptosis and
autophagy of gastric cancer cells by suppressing PI3K/Akt/mTOR
pathway. Exp Cell Res. 385:1116912019. View Article : Google Scholar
|
|
62
|
Ding R, Wang X, Chen W, Li Z, Wei AL, Wang
QB, Nie AH and Wang LL: WX20120108, a novel IAP antagonist, induces
tumor cell autophagy via activating ROS-FOXO pathway. Acta
Pharmacol Sin. 40:1466–1479. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Tsuboyama K, Koyama-Honda I, Sakamaki Y,
Koike M, Morishita H and Mizushima N: The ATG conjugation systems
are important for degradation of the inner autophagosomal membrane.
Science. 354:1036–1041. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Xu Z, Han X, Ou D, Liu T, Li Z, Jiang G,
Liu J and Zhang J: Targeting PI3K/AKT/mTOR-mediated autophagy for
tumor therapy. Appl Microbiol Biotechnol. 104:575–587. 2020.
View Article : Google Scholar
|
|
65
|
Höglund R, Moussavi Y, Ruengweerayut R,
Cheomung A, Äbelö A and Na-Bangchang K: Population pharmacokinetics
of a three-day chloroquine treatment in patients with Plasmodium
vivax infection on the Thai-Myanmar border. Malar J. 15:1292016.
View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Maycotte P, Aryal S, Cummings CT, Thorburn
J, Morgan MJ and Thorburn A: Chloroquine sensitizes breast cancer
cells to chemotherapy independent of autophagy. Autophagy.
8:200–212. 2012. View Article : Google Scholar : PubMed/NCBI
|
