Molecular signaling in death receptor and mitochondrial pathways of apoptosis (Review)

  • Authors:
    • Sudhir Gupta
  • View Affiliations

  • Published online on: January 1, 2003     https://doi.org/10.3892/ijo.22.1.15
  • Pages: 15-20
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

In recent years major progress has been made in understanding the molecular steps of death receptor and mitochondrial pathway of apoptosis. Mechanisms of NF-κB-mediated survival (anti-apoptotic) signal have been delineated. A novel anti-apoptotic mechanism of FLIP in the recruitment of RIP and TRAF-1 and TRAF-2 to activate ERK and NF-κB has been defined. These are some of the recent discoveries in death receptor and mitochondrial pathways of apoptosis that have been reviewed in this article.

Related Articles

Journal Cover

January 2003
Volume 22 Issue 1

Print ISSN: 1019-6439
Online ISSN:1791-2423

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Gupta S: Molecular signaling in death receptor and mitochondrial pathways of apoptosis (Review). Int J Oncol 22: 15-20, 2003.
APA
Gupta, S. (2003). Molecular signaling in death receptor and mitochondrial pathways of apoptosis (Review). International Journal of Oncology, 22, 15-20. https://doi.org/10.3892/ijo.22.1.15
MLA
Gupta, S."Molecular signaling in death receptor and mitochondrial pathways of apoptosis (Review)". International Journal of Oncology 22.1 (2003): 15-20.
Chicago
Gupta, S."Molecular signaling in death receptor and mitochondrial pathways of apoptosis (Review)". International Journal of Oncology 22, no. 1 (2003): 15-20. https://doi.org/10.3892/ijo.22.1.15