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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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September 1994 Volume 5 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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September 1994 Volume 5 Issue 3

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Article

FLOW CYTOMETRIC DNA ANALYSIS IN PREDICTION OF INTRAVESICAL RECURRENCE FROM HUMAN BLADDER-CANCER

  • Authors:
    • A RUSSO
    • V BAZAN
    • R CAMPANELLA
    • G DARDANONI
    • I CARRECA
    • S CUCCIARRE
    • A VECCHIONE
    • M PAVONEMACALUSO

  • View Affiliations / Copyright

    Affiliations: UNIV PALERMO,POLICLIN UNIV P GIACCONE,CTR INTERDIPT RIC ONCOL CLIN,ONCOL SPERIMENTALE LAB,I-90127 PALERMO,ITALY. UNIV PALERMO,POLICLIN UNIV P GIACCONE,IST CLIN UROL,I-90127 PALERMO,ITALY. UNIV PALERMO,POLICLIN UNIV P GIACCONE,CTR INTERDIPT RIC ONCOL CLIN,CATTEDRA ONCOL MED,I-90127 PALERMO,ITALY. UNIV PALERMO,POLICLIN UNIV P GIACCONE,IST RADIOL,CITOPATOL SEZ,I-90127 PALERMO,ITALY. OSSERVATORIO EPIDEMIOL REG SICILIANA,I-90145 PALERMO,ITALY. UNIV ROMA LA SAPIENZA,DIPARTIMENTO MED SPERIMENTALE,CATTEDRA CITOPATOL 1,I-00161 ROME,ITALY.
  • Pages: 633-638
    |
    Published online on: September 1, 1994
       https://doi.org/10.3892/ijo.5.3.633
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Abstract

A series of 128 patients undergoing diagnostic and/or therapeutic transurethral resection for primary urothelial bladder carcinoma was prospectively studied in order to evaluate the relative importance of DNA-ploidy and S-phase fraction (SPF) by flow cytometry and of several clinicopathological features in predicting disease-free survival. Only frozen tissue was used. The mean follow-up was 22 months (range: 3-61 months). DNA-aneuploidy was present in 64% of the cases (82/128), while multiclonality was found in 29% of the DNA-aneuploid cases (24/82). In the univariate statistical analysis, high stage, DNA-aneuploidy (mono- and multiclonal patterns) and high SPF value (>11.6%) proved to be significantly related to the risk of intravesical recurrence, while a significant trend was present for histological grade. In the multivariate analysis only high SPF value (>11.6%) and DNA-aneuploidy were independently related to risk of relapse (RR of 2.39 and 2.40 respectively).

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Copy and paste a formatted citation
Spandidos Publications style
RUSSO A, BAZAN V, CAMPANELLA R, DARDANONI G, CARRECA I, CUCCIARRE S, VECCHIONE A and PAVONEMACALUSO M: FLOW CYTOMETRIC DNA ANALYSIS IN PREDICTION OF INTRAVESICAL RECURRENCE FROM HUMAN BLADDER-CANCER. Int J Oncol 5: 633-638, 1994.
APA
RUSSO, A., BAZAN, V., CAMPANELLA, R., DARDANONI, G., CARRECA, I., CUCCIARRE, S. ... PAVONEMACALUSO, M. (1994). FLOW CYTOMETRIC DNA ANALYSIS IN PREDICTION OF INTRAVESICAL RECURRENCE FROM HUMAN BLADDER-CANCER. International Journal of Oncology, 5, 633-638. https://doi.org/10.3892/ijo.5.3.633
MLA
RUSSO, A., BAZAN, V., CAMPANELLA, R., DARDANONI, G., CARRECA, I., CUCCIARRE, S., VECCHIONE, A., PAVONEMACALUSO, M."FLOW CYTOMETRIC DNA ANALYSIS IN PREDICTION OF INTRAVESICAL RECURRENCE FROM HUMAN BLADDER-CANCER". International Journal of Oncology 5.3 (1994): 633-638.
Chicago
RUSSO, A., BAZAN, V., CAMPANELLA, R., DARDANONI, G., CARRECA, I., CUCCIARRE, S., VECCHIONE, A., PAVONEMACALUSO, M."FLOW CYTOMETRIC DNA ANALYSIS IN PREDICTION OF INTRAVESICAL RECURRENCE FROM HUMAN BLADDER-CANCER". International Journal of Oncology 5, no. 3 (1994): 633-638. https://doi.org/10.3892/ijo.5.3.633
Copy and paste a formatted citation
x
Spandidos Publications style
RUSSO A, BAZAN V, CAMPANELLA R, DARDANONI G, CARRECA I, CUCCIARRE S, VECCHIONE A and PAVONEMACALUSO M: FLOW CYTOMETRIC DNA ANALYSIS IN PREDICTION OF INTRAVESICAL RECURRENCE FROM HUMAN BLADDER-CANCER. Int J Oncol 5: 633-638, 1994.
APA
RUSSO, A., BAZAN, V., CAMPANELLA, R., DARDANONI, G., CARRECA, I., CUCCIARRE, S. ... PAVONEMACALUSO, M. (1994). FLOW CYTOMETRIC DNA ANALYSIS IN PREDICTION OF INTRAVESICAL RECURRENCE FROM HUMAN BLADDER-CANCER. International Journal of Oncology, 5, 633-638. https://doi.org/10.3892/ijo.5.3.633
MLA
RUSSO, A., BAZAN, V., CAMPANELLA, R., DARDANONI, G., CARRECA, I., CUCCIARRE, S., VECCHIONE, A., PAVONEMACALUSO, M."FLOW CYTOMETRIC DNA ANALYSIS IN PREDICTION OF INTRAVESICAL RECURRENCE FROM HUMAN BLADDER-CANCER". International Journal of Oncology 5.3 (1994): 633-638.
Chicago
RUSSO, A., BAZAN, V., CAMPANELLA, R., DARDANONI, G., CARRECA, I., CUCCIARRE, S., VECCHIONE, A., PAVONEMACALUSO, M."FLOW CYTOMETRIC DNA ANALYSIS IN PREDICTION OF INTRAVESICAL RECURRENCE FROM HUMAN BLADDER-CANCER". International Journal of Oncology 5, no. 3 (1994): 633-638. https://doi.org/10.3892/ijo.5.3.633
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