Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies

  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular and Clinical Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9450 Online ISSN: 2049-9469
Journal Cover
November-December 2014 Volume 2 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
November-December 2014 Volume 2 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Case Report

Malignant peripheral nerve sheath tumor in the anterior mediastinum: A case report

  • Authors:
    • Satoshi Koezuka
    • Yoshinobu Hata
    • Fumitomo Sato
    • Hajime Otsuka
    • Takashi Makino
    • Naobumi Tochigi
    • Akira Iyoda

  • View Affiliations / Copyright

    Affiliations: Division of Chest Surgery, School of Medicine, Toho University, Tokyo 143‑8541, Japan, Department of Surgical Pathology, School of Medicine, Toho University, Tokyo 143‑8541, Japan
  • Pages: 987-990
    |
    Published online on: July 9, 2014
       https://doi.org/10.3892/mco.2014.343
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Malignant peripheral nerve sheath tumors (MPNSTs) are rare neoplasms, accounting for only 5% of all malignant soft‑tissue sarcomas. This is the case report of a 28‑year‑old male patient with a MPNST located in the anterior mediastinum, originating from the phrenic nerve. The patient presented with an abnormal shadow on chest radiography and a 10‑cm mass in the right anterior mediastinum was identified on computed tomography and magnetic resonance imaging. The patient subsequently underwent surgical resection. The tumor originated from the right phrenic nerve and was tightly adherent to the middle and lower lobes of the right lung, the pericardium and the diaphragm. The tumor was completely resected, along with partial resection of the adherent tissues. The histological diagnosis was spindle cell sarcoma and the final diagnosis was MPNST of the anterior mediastinum, based on the characteristic microscopic appearance indicating the nervous origin of the tumor and on the intraoperative findings. The patient remains free of recurrence 1 year after surgery.
View Figures

Figure 1

Figure 2

View References

1 

Nielsen GP, Antonescu CR and Lothe RA: Malignant peripheral nerve sheath tumour. WHO Classification of Tumours of Soft Tissue and Bone. Fletcher CDM, Bridge JA, Hogendoorn PCD and Mertens F: 5. 4th edition. IARC Press; Lyon: pp. 187–189. 2013

2 

Italiano A, Delva F, Mathoulin-Pelissier S, et al: Effect of adjuvant chemotherapy on survival in FNCLCC grade 3 soft tissue sarcomas: a multivariate analysis of the French Sarcoma Group Database. Ann Oncol. 21:2436–2441. 2010. View Article : Google Scholar : PubMed/NCBI

3 

Sugio K, Inoue T, Inoue K, et al: Neurogenic tumors of the mediastinum originated from the vagus nerve. Eur J Surg Oncol. 21:214–216. 1995. View Article : Google Scholar : PubMed/NCBI

4 

Ingels GW, Campbell DC Jr, Giampetro AM, Kozub RE and Bentlage CH: Malignant schwannomas of the mediastinum. Report of two cases and review of the literature. Cancer. 27:1190–1201. 1971. View Article : Google Scholar : PubMed/NCBI

5 

Ducatman BS and Scheithauer BW: Malignant peripheral nerve sheath tumors with divergent differentiation. Cancer. 54:1049–1057. 1984. View Article : Google Scholar : PubMed/NCBI

6 

Otani Y, Morishita Y, Yoshida I, et al: A malignant Triton tumor in the anterior mediastinum requiring emergency surgery: report of a case. Surg Today. 26:834–836. 1996. View Article : Google Scholar : PubMed/NCBI

7 

Zisis C, Fragoulis S, Rontogianni D, Stratakos G and Bellenis I: Malignant triton tumour of the anterior mediastinum as incidental finding. Monaldi Arch Chest Dis. 65:222–224. 2006.PubMed/NCBI

8 

Shimoyama T, Yoshida K, Yamoto Y, Koike T and Honma K: Long-term survival after removal of a malignant peripheral nerve sheath tumor originating in the anterior mediastinum. Gen Thorac Cardiovasc Surg. 57:310–314. 2009. View Article : Google Scholar : PubMed/NCBI

9 

Ducatman BS, Scheithauer BW, Piepgras DG, Reiman HM and Ilstrup DM: Malignant peripheral nerve sheath tumors. A clinicopathologic study of 120 cases. Cancer. 57:2006–2021. 1986. View Article : Google Scholar : PubMed/NCBI

10 

Wong WW, Hirose T, Scheithauer BW, Schild SE and Gunderson LL: Malignant peripheral nerve sheath tumor: analysis of treatment outcome. Int J Radiat Oncol Biol Phys. 42:351–360. 1998. View Article : Google Scholar : PubMed/NCBI

11 

Carli M, Ferrari A, Mattke A, et al: Pediatric malignant peripheral nerve sheath tumor: the Italian and German soft tissue sarcoma cooperative group. J Clin Oncol. 23:8422–8430. 2005. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Koezuka S, Hata Y, Sato F, Otsuka H, Makino T, Tochigi N and Iyoda A: Malignant peripheral nerve sheath tumor in the anterior mediastinum: A case report. Mol Clin Oncol 2: 987-990, 2014.
APA
Koezuka, S., Hata, Y., Sato, F., Otsuka, H., Makino, T., Tochigi, N., & Iyoda, A. (2014). Malignant peripheral nerve sheath tumor in the anterior mediastinum: A case report. Molecular and Clinical Oncology, 2, 987-990. https://doi.org/10.3892/mco.2014.343
MLA
Koezuka, S., Hata, Y., Sato, F., Otsuka, H., Makino, T., Tochigi, N., Iyoda, A."Malignant peripheral nerve sheath tumor in the anterior mediastinum: A case report". Molecular and Clinical Oncology 2.6 (2014): 987-990.
Chicago
Koezuka, S., Hata, Y., Sato, F., Otsuka, H., Makino, T., Tochigi, N., Iyoda, A."Malignant peripheral nerve sheath tumor in the anterior mediastinum: A case report". Molecular and Clinical Oncology 2, no. 6 (2014): 987-990. https://doi.org/10.3892/mco.2014.343
Copy and paste a formatted citation
x
Spandidos Publications style
Koezuka S, Hata Y, Sato F, Otsuka H, Makino T, Tochigi N and Iyoda A: Malignant peripheral nerve sheath tumor in the anterior mediastinum: A case report. Mol Clin Oncol 2: 987-990, 2014.
APA
Koezuka, S., Hata, Y., Sato, F., Otsuka, H., Makino, T., Tochigi, N., & Iyoda, A. (2014). Malignant peripheral nerve sheath tumor in the anterior mediastinum: A case report. Molecular and Clinical Oncology, 2, 987-990. https://doi.org/10.3892/mco.2014.343
MLA
Koezuka, S., Hata, Y., Sato, F., Otsuka, H., Makino, T., Tochigi, N., Iyoda, A."Malignant peripheral nerve sheath tumor in the anterior mediastinum: A case report". Molecular and Clinical Oncology 2.6 (2014): 987-990.
Chicago
Koezuka, S., Hata, Y., Sato, F., Otsuka, H., Makino, T., Tochigi, N., Iyoda, A."Malignant peripheral nerve sheath tumor in the anterior mediastinum: A case report". Molecular and Clinical Oncology 2, no. 6 (2014): 987-990. https://doi.org/10.3892/mco.2014.343
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team