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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-December 2014 Volume 2 Issue 6

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Journal Metrics

Impact Factor: 1.4

CiteScore: 2.8

CiteScore Rank: Q3: #254/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.55

SCImago Journal Rank (SJR): 0.446

Review

Utilising proteomic approaches to understand oncogenic human herpesviruses (Review)

Christopher B. Owen, David J. Hughes, Belinda Baquero-Perez, Anja Berndt, Sophie Schumann, Brian R. Jackson, Adrian Whitehouse
Pages: 891-903
Published online on: 09 July 2014

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Article

Passive targeting of nanoparticles to cancer: A comprehensive review of the literature

Remon Bazak, Mohamad Houri, Samar El Achy, Wael Hussein, Tamer Refaat
Pages: 904-908
Published online on: 23 July 2014

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Review

Features of ovarian cancer in Lynch syndrome (Review)

Kanako Nakamura, Kouji Banno, Megumi Yanokura, Miho Iida, Masataka Adachi, Kenta Masuda, Arisa Ueki, Yusuke Kobayashi, Hiroyuki Nomura, Akira Hirasawa, Eiichiro Tominaga, Daisuke Aoki
Pages: 909-916
Published online on: 20 August 2014

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Review

Management of lymph node metastases from an unknown primary site to the head and neck (Review)

Shi Min Zhuang, Xi‑Fu Wu, Jing‑Jia Li, Ge‑Hua Zhang
Pages: 917-922
Published online on: 29 July 2014

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Article

Clinical experience with plerixafor as a mobilization regimen for autologous peripheral blood stem cell transplantation in patients with refractory germ cell tumors

Ignacio García‑Escobar, Lucía Parrilla, Laura Montejano Ortega, Daniel Castellanos, María Ángeles Montalbán Pallarés, Hernán Cortés‑Funés
Pages: 923-926
Published online on: 29 July 2014

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Article

Time trends of clinical characteristics in hepatocellular carcinoma patients with chronic hepatitis B virus infection: A field survey between 2000 and 2012

Keisuke Amano, Takumi Kawaguchi, Ryoko Kuromatsu, Atsushi Kawaguchi, Ichiro Miyajima, Tatsuya Ide, Tatsuyuki Kakuma, Michio Sata
Pages: 927-934
Published online on: 21 August 2014

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Article

Synergistic interactions of the anti‑casein kinase 2 CIGB‑300 peptide and chemotherapeutic agents in lung and cervical preclinical cancer models

Yasser Perera, Neylen Del Toro, Larisa Gorovaya, Jorge Fernandez‑De‑Cossio, Hernan G. Farina, Silvio E. Perea
Pages: 935-944
Published online on: 08 July 2014

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Case Report

Precursor T‑cell lymphoblastic lymphoma extensively involving the mediastinum, pleura and pericardium: A case report

Xianhong Xiang, Xiaoyan Wang, Qinqin Yi, Lin Lin, Xiangsong Zhang, Hong Liang, Jianyong Yang
Pages: 945-948
Published online on: 11 July 2014

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Case Report

Double primary hepatic cancer (sarcomatoid carcinoma and hepatocellular carcinoma): A case report

Ji‑Woon Lee, Man‑Woo Kim, Nam‑Kyu Choi, In‑Ju Cho, Ran Hong
Pages: 949-952
Published online on: 26 August 2014

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Article

Rechallenge with pemetrexed-based chemotherapy improves the survival of patients with advanced non-squamous non-small‑cell lung cancer

Ming-Lei Zhuo, Hua Bai, Zhi-Jie Wang, Jian-Chun Duan, Tong-Tong An, Mei-Na Wu, Jun Zhao, Yu-Yan Wang, Shu-Hang Wang, Jie Wang
Pages: 953-959
Published online on: 24 July 2014

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Article

Bladder extragastrointestinal stromal tumor in an adolescent patient: A case‑based review

Fan He, Zhenqiang Fang, Pei Zhu, Wei Huang, Longkun Li
Pages: 960-962
Published online on: 31 July 2014

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Article

Lymph node spread of gallbladder cancer from the perspective of embryologically‑based anatomy and significance of the lymphatic basin along the embryonic right hepatic artery

Hisatoshi Nakagawara, Hidehiro Tajima, Tomoharu Miyashita, Hirohisa Kitagawa, Isamu Makino, Seisho Sakai, Hironori Hayashi, Shinichi Nakanuma, Katsunobu Oyama, Hiroyuki Takamura, Sachio Fushida, Takashi Fujimura, Tetsuo Ohta
Pages: 963-967
Published online on: 09 July 2014

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Article

Mechanism underlying the transient increase of serum iron during FOLFOX/FOLFIRI therapy

Takumi Ochiai, Kazuhiko Nishimura, Tomoo Watanabe, Masayuki Kitajima, Akinori Nakatani, Tsuyoshi Sato, Kenji Kishine, Shunji Futagawa, Satomi Mashiko, Isao Nagaoka
Pages: 968-972
Published online on: 11 August 2014

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Article

Overexpression of membrane‑type 2 matrix metalloproteinase induced by hypoxia‑inducible factor‑1α in pancreatic cancer: Implications for tumor progression and prognosis

Shi‑Kai Zhu, Yu Zhou, Chao Cheng, Shan Zhong, Han‑Qing Wu, Bo Wang, Ping Fan, Jiong‑Xin Xiong, Hong‑Ji Yang, He‑Shui Wu
Pages: 973-981
Published online on: 23 July 2014

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Article

Predominance of ERG‑negative high‑grade prostate cancers in African American men

James Farrell, Denise Young, Yongmei Chen, Jennifer Cullen, Inger L. Rosner, Jacob Kagan, Sudhir Srivastava, David G. McLeod, Isabell A. Sesterhenn, Shiv Srivastava, Gyorgy Petrovics
Pages: 982-986
Published online on: 07 August 2014

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Case Report

Malignant peripheral nerve sheath tumor in the anterior mediastinum: A case report

Satoshi Koezuka, Yoshinobu Hata, Fumitomo Sato, Hajime Otsuka, Takashi Makino, Naobumi Tochigi, Akira Iyoda
Pages: 987-990
Published online on: 09 July 2014

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Article

Phase II study of erlotinib for previously treated patients with EGFR wild‑type non‑small‑cell lung cancer, following EGFR mutation status reevaluation with the Scorpion Amplified Refractory Mutation System

Masahiro Morise, Hiroyuki Taniguchi, Hideo Saka, Joe Shindoh, Ryujiro Suzuki, Eiji Kojima, Tetsunari Hase, Masahiko Ando, Masashi Kondo, Hiroshi Saito, Yoshinori Hasegawa
Pages: 991-996
Published online on: 22 July 2014

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Article

Long‑term outcomes following adjuvant endocrine therapy in breast cancer patients with a positive‑to‑negative change of hormone receptor status following neoadjuvant chemotherapy

Jia Yi Wu, Wei Guo Chen, Xiao Song Chen, Ou Huang, Jian Rong He, Li Zhu, Yafen Li, Kun Wei Shen
Pages: 997-1002
Published online on: 31 July 2014

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Article

Placement of self‑expandable metallic stents for tracheal stenosis secondary to thyroid cancer

Rena Yuasa, Yoshinobu Hata, Hajime Otsuka, Takashi Makino, Satoshi Koezuka, Fumitomo Sato, Kazuyoshi Tamaki, Shuichi Sasamoto, Keigo Takagi, Akira Iyoda
Pages: 1003-1008
Published online on: 17 July 2014

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Article

Apolipoprotein E genetic polymorphism, serum lipoprotein levels and breast cancer risk: A case-control study

Gabriela Herrmann Cibeira, Juliana Giacomazzi, Ernestina Aguiar, Silvana Schneider, Betina Ettrich, Caroline Isoppo De Souza, Suzi Camey, Maira Caleffi, Bernardete Weber, Patricia Ashton-Prolla, Emilio Hideyuki Moriguchi
Pages: 1009-1015
Published online on: 01 August 2014

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Article

Ritonavir acts synergistically with panobinostat to enhance histone acetylation and inhibit renal cancer growth

Akinori Sato, Takako Asano, Makoto Isono, Keiichi Ito, Tomohiko Asano
Pages: 1016-1022
Published online on: 15 July 2014

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Article

Granulocyte macrophage colony‑stimulating factor as a predictor of the response of metastatic renal cell carcinoma to tyrosine kinase inhibitor therapy

Daisuke Yamada, Hirokazu Matsushita, Takeshi Azuma, Tohru Nakagawa, Masayoshi Nagata, Yukio Yamada, Motofumi Suzuki, Tetsuya Fujimura, Hiroshi Fukuhara, Haruki Kume, Yukio Homma, Kazuhiro Kakimi
Pages: 1023-1027
Published online on: 29 July 2014

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Article

Comparison of hepatic arterial infusion chemotherapy and sorafenib in elderly patients with advanced hepatocellular carcinoma: A case series

Tomoyuki Nemoto, Hidetaka Matsuda, Takuto Nosaka, Yasushi Saito, Yoshihiko Ozaki, Ryoko Hayama, Tatsushi Naito, Kazuto Takahashi, Kazuya Ofuji, Masahiro Ohtani, Katsushi Hiramatsu, Hiroyuki Suto, Yasunari Nakamoto
Pages: 1028-1034
Published online on: 05 August 2014

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Article

PD‑1 gene promoter polymorphisms correlate with a poor prognosis in non‑small cell lung cancer

Hidefumi Sasaki, Tsutomu Tatemaysu, Katsuhiro Okuda, Satoru Moriyama, Motoki Yano, Yoshitaka Fujii
Pages: 1035-1042
Published online on: 24 July 2014

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Article

Ginsenoside Rg3 enhances the inhibitory effects of chemotherapy on esophageal squamous cell carcinoma in mice

Liang Chang, Bingjie Huo, Yalei Lv, Yudong Wang, Wei Liu
Pages: 1043-1046
Published online on: 23 July 2014

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Article

Transarterial chemoembolization vs. conservative treatment for unresectable infiltrating hepatocellular carcinoma: A retrospective comparative study

Qiang‑Sheng Dai, Hong‑Lin Gu, Sheng Ye, Yao‑Jun Zhang, Xiao‑Jun Lin, Wan Yee Lau, Zhen‑Wei Peng, Min‑Shan Chen
Pages: 1047-1054
Published online on: 18 August 2014

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Article

Prognostic significance of the co‑expression of nucleophosmin and trefoil factor 3 in postoperative gastric cancer patients

Yong Li, Zhenqing Sun, Kewei Liu, Wensheng Qiu, Ruyong Yao, Tongtong Feng, Chao Xin, Lu Yue
Pages: 1055-1061
Published online on: 17 July 2014

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Article Open Access

Prognostic significance of Ki-67 index value at the primary breast tumor in recurrent breast cancer

Reiki Nishimura, Tomofumi Osako, Yasuyuki Nishiyama, Rumiko Tashima, Masahiro Nakano, Mamiko Fujisue, Yasuo Toyozumi, Nobuyuki Arima
Pages: 1062-1068
Published online on: 22 August 2014

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Article

Survival outcomes and progonostic factors of extrahepatic cholangiocarcinoma patients following surgical resection: Adjuvant therapy is a favorable prognostic factor

Haixia Yang, Jiupeng Zhou, Xin Wei, Fan Wang, Huadong Zhao, Enxiao Li
Pages: 1069-1075
Published online on: 07 August 2014

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Article

Association of a disintegrin and metalloprotease 33 gene polymorphisms with asthma

Nigela Yilihamu, Qimangul Wushouer, Kadirya Arkin, Hu Xin, Umesh Yadav
Pages: 1076-1080
Published online on: 09 July 2014

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Article

Εxpression of enoyl coenzyme a hydratase, short chain, 1, in colorectal cancer and its association with clinicopathological characteristics

Jun-Pei Xie, Xiao-San Zhu, Yi-Chen Dai, Cui Yu, Tao Xie, Zhang-Xing Chen
Pages: 1081-1084
Published online on: 09 July 2014

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Article

Learning curve of endorectal ultrasonography in preoperative staging of rectal carcinoma

Zuo-Liang Liu, Tong Zhou, Xiao-Bo Liang, Jun-Jie Ma, Guang-Jun Zhang
Pages: 1085-1090
Published online on: 17 July 2014

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Article

Conventional oral systemic chemotherapy for postoperative hepatocellular carcinoma: A systematic review

Jianhong Zhong, Bangde Xiang, Liang Ma, Lequn Li
Pages: 1091-1096
Published online on: 07 July 2014

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Article

Laparoscopic versus open surgery for rectal cancer: Results of a systematic review and meta‑analysis on clinical efficacy

Jun‑Kang Zhao, Nan‑Zheng Chen, Jian‑Bao Zheng, Sai He, Xue‑Jun Sun
Pages: 1097-1102
Published online on: 11 July 2014

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Article

Safety of repeated cell‑free and concentrated ascites reinfusion therapy for malignant ascites from gastrointestinal cancer

Osamu Maeda, Takafumi Ando, Kazuhiro Ishiguro, Osamu Watanabe, Ryoji Miyahara, Masanao Nakamura, Kohei Funasaka, Furukawa Kazuhiro, Yuichi Ando, Hidemi Goto
Pages: 1103-1106
Published online on: 04 July 2014

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Article

Lack of HER-2 gene amplification and association with pathological and clinical characteristics of differentiated thyroid cancer

Wahid Mdah, Raneen Mzalbat, Peter Gilbey, Moshe Stein, Adi Sharabi, Jamal Zidan
Pages: 1107-1110
Published online on: 11 July 2014

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Article

Pre‑chemotherapy preservation of fertility in male patients with high‑grade malignant bone and soft tissue tumors

Manabu Hoshi, Naoto Oebisu, Jun Takada, Tadashi Iwai, Rie Tsuruta, Hiroaki Nakamura
Pages: 1111-1114
Published online on: 01 August 2014

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Article

Alcohol consumption and risk of myelodysplastic syndromes: A meta‑analysis of epidemiological studies

Jie Jin, Mengxia Yu, Chao Hu, Li Ye, Lili Xie, Feifei Chen, Zhengping Zhuang, Hongyan Tong
Pages: 1115-1120
Published online on: 07 August 2014

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Article

p16 promoter hypermethylation is associated with increased risk of nasopharyngeal carcinoma

Yang Shao, Hongguo Jiang, Xiaoming Wu, Ying Luo, Wenru Tang
Pages: 1121-1124
Published online on: 20 August 2014

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Article

Adjuvant interferon for early or late recurrence of hepatocellular carcinoma and mortality from hepatocellular carcinoma following curative treatment: A meta‑analysis with comparison of different types of hepatitis

Wei Zhang, Tian‑Qiang Song, Ti Zhang, Qiang Wu, Da‑Lu Kong, Qiang Li, Hui‑Chuan Sun
Pages: 1125-1134
Published online on: 12 August 2014

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Article

Curative effect of stereotactic body radiotherapy on hepatic hilar carcinoma

Ya‑Zheng Dang, Shi‑Gao Huang, Wan‑Ling Lu, Fa‑Wei Wu, Qian‑Yun Wang
Pages: 1135-1138
Published online on: 20 August 2014

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Article

Metadherin in prostate, bladder, and kidney cancer: A systematic review

Zhao Wang, Yong‑Bao Wei, Yun‑Liang Gao, Bin Yan, Jin‑Rui Yang, Qiong Guo
Pages: 1139-1144
Published online on: 18 August 2014

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Article

Upgrading and upstaging in prostate cancer: From prostate biopsy to radical prostatectomy

Carolina D'Elia, Maria Angela Cerruto, Antonio Cioffi, Giovanni Novella, Stefano Cavalleri, Walter Artibani
Pages: 1145-1149
Published online on: 05 August 2014

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Article

Radiotherapy and chemoradiotherapy as a novel option for the treatment of locally advanced inoperable gastric adenocarcinoma: A phase II study

Jerzy Wydmanski, Kinga Grabinska, Pawel Polanowski, Agnieszka Namysl‑Kaletka, Rafal Kawczynski, Malgorzata Kraszkiewicz, Wojciech Majewski
Pages: 1150-1154
Published online on: 11 July 2014

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Article

XAGE‑1b expression is associated with the diagnosis and early recurrence of hepatocellular carcinoma

Zeya Pan, Bikui Tang, Zhenyu Hou, Jin Zhang, Hui Liu, Yuan Yang, Gang Huang, Yun Yang, Weiping Zhou
Pages: 1155-1159
Published online on: 04 July 2014

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Article

Expression of acidosis‑dependent genes in human cancer nests

Toshihiko Fukamachi, Shunsuke Ikeda, Hiromi Saito, Masatoshi Tagawa, Hiroshi Kobayashi
Pages: 1160-1166
Published online on: 11 July 2014

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Article

Study of the effectiveness of first‑line treatment in renal cell carcinoma

Alejandro J. Sastre‑Heres, Miguel Alaguero Calero, Daniel Ruiz‑Sánchez, María Teresa Iglesias García, Miguel Angel Calleja Hernandez, Fernando Martínez Martínez, Jaime Peña‑Díaz
Pages: 1167-1171
Published online on: 18 July 2014

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Article

Efficacy of gemcitabine combined with oxaliplatin, L‑asparaginase and dexamethasone in patients with newly‑diagnosed extranodal NK/T‑cell lymphoma

Hong‑Qiang Guo, Lei Liu, Xin‑Feng Wang, Tong‑Yu Lin, Shu‑Na Yao, Zhi‑Hua Yao, Shu‑Jun Yang
Pages: 1172-1176
Published online on: 01 August 2014

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Article

Association of xeroderma pigmentosum complementation group G Asp1104His polymorphism with breast cancer risk: A cumulative meta‑analysis

Xiao‑Ming Xu, Long‑Chuan Xie, Ling‑Ling Yuan, Xiao‑Li Hu, Jian‑Qiang Jin, Yu‑Ming Niu
Pages: 1177-1181
Published online on: 11 August 2014

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Article

Docetaxel-based therapy with and without antiangiogenic agents as first-line chemotherapy for castration-resistant prostate cancer: A meta-analysis of nine randomized controlled trials

Naijun Lei, Zhengfang Song, Bing Lu, Zheng Tan, Jiao Pei, Wusong Liu, Ke Xu
Pages: 1182-1188
Published online on: 26 August 2014

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Journal Cover
January-2026 Volume 24 Issue 1

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Journal Metrics

Impact Factor: 1.4

CiteScore: 2.8

CiteScore Rank: Q3: #254/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.55

SCImago Journal Rank (SJR): 0.446

Article Open Access

D‑dimer as a more effective marker for detecting thrombosis in patients with ovarian clear cell carcinoma compared with high‑grade serous carcinoma

Tsubasa Ito, Morikazu Miyamoto, Risa Tanabe, Soko Nishimura, Naohisa Kishimoto, Jin Suminokura, Taira Hada, Yuka Otsuka, Kento Kato, Hiroaki Soyama, Kohei Omatsu, Yoshinobu Hamada, Masashi Takano
Article Number: 10
Published online on: 26 November 2025

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Article Open Access

A prognostic gene signature derived from aging‑related genes predicts survival, immune landscape and therapy response in glioma

Zhenzhe Li, Liuyue Zhang, Xiaopeng Li, Peng Luo, Xingbo Liang, Tao Wen, Jieqin Yao, Qingwang Yu, Qianshuo Zhong
Article Number: 9
Published online on: 24 November 2025

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Article

Role of posterosuperior pancreatic lymph nodes in gallbladder cancer: A study using the efficacy index

Kenji Yoshino, Sora Nishizaki, Hironobu Tosa, Shohei Yokoyama, Hiroaki Fuji, Toshiyuki Hata, Takahisa Kyogoku, Atsushi Itami
Article Number: 8
Published online on: 20 November 2025

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Review

Tertiary lymphoid structure can be a potential therapeutic target for head and neck squamous cell carcinoma (Review)

Jie Shen, Xiao Yang
Article Number: 7
Published online on: 14 November 2025

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Article

Impact of TAS‑102 dose reduction on severe neutropenia and survival outcomes in patients with metastatic colorectal cancer and prior chemotherapy‑induced neutropenia

Chihiro Suzuki, Michio Kimura, Makiko Go, Yoshiaki Ikeda, Eiseki Usami
Article Number: 6
Published online on: 07 November 2025

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Article Open Access

Contributions of ADAM12 via HB‑EGF/EGFR signaling cascades to EMT and cancer progression in pancreas

Qiubo Zhang, Feng Xu, Zetian Gao, Xianwen Dong, Yanyan Ma, Hong Li, Kaihong Huang
Article Number: 5
Published online on: 07 November 2025

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Drug resistance in glioblastoma: Challenges, mechanisms and therapeutic strategies (Review)

Yash K. Durga, Raju V. Pusapati
Article Number: 4
Published online on: 06 November 2025

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A 4‑cuproptosis‑related lncRNA theragnostic signature predicts survival and immunotherapy response in patients with lung adenocarcinoma

Lina Lu, Yinyin Qin, Mingdeng Wang, Yanjun Deng, Yuansheng Lin
Article Number: 3
Published online on: 30 October 2025

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Advances in the basic function of the small GTPase SAR1B and its regulatory role in the biological behavior of tumor cells (Review)

Qingchun Yang, Guodong Huang, Chi Lu, Zhang Lei, Hongda Lu
Article Number: 2
Published online on: 30 October 2025

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Prognostic significance of ductal carcinoma in situ coexisting with invasive ductal carcinoma: Biological behavior, immune response and survival outcomes

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Article Number: 1
Published online on: 27 October 2025

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February-2026 Volume 24 Issue 2

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Journal Metrics

Impact Factor: 1.4

CiteScore: 2.8

CiteScore Rank: Q3: #254/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.55

SCImago Journal Rank (SJR): 0.446

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TTF‑1 expression is associated with survival in patients with non‑squamous non‑small cell lung cancer treated with immune checkpoint inhibitor therapy

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Article Number: 11
Published online on: 28 November 2025

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