Palliative sequential chemoradiotherapy for pulmonary sulcus tumor: A case report

Kikuchi,Miki; Ohtani,Toshihiro; Tamura,Tomohiro; Satoh,Hiroaki

doi:10.3892/mco.2016.1026

November-2016 Volume 5 Issue 5

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November-2016 Volume 5 Issue 5

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Case Report

Palliative sequential chemoradiotherapy for pulmonary sulcus tumor: A case report

Authors:
- Miki Kikuchi
- Toshihiro Ohtani
- Tomohiro Tamura
- Hiroaki Satoh
View Affiliations / Copyright

Affiliations: Division of Nursing, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310‑0015, Japan, Division of Pharmacy, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310‑0015, Japan, Division of Respiratory Medicine, Mito Medical Center, University of Tsukuba, Mito, Ibaraki 310‑0015, Japan
Pages: 651-652
|
Published online on: September 21, 2016

https://doi.org/10.3892/mco.2016.1026
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Abstract

Pulmonary sulcus tumors are occasionally encountered in non‑small-cell lung cancer (NSCLC) patients. If the patients have a good clinical condition, concurrent chemoradiotherapy is indicated. However, palliative chemotherapy and chemoradiotherapy for patients exhibiting a poor overall condition have not been reported to date. We herein report the case of a 54‑year‑old female patient with a pulmonary sulcus tumor, who had a poor performance status. The patient received sequential chemoradiotherapy, with no severe complications. There was no local recurrence until the time of death, 8 months after the initiation of therapy. Palliative sequential chemoradiotherapy for pulmonary sulcus NSCLC must be effective and carry low risk of complications. Palliative sequential chemoradiotherapy may be considered in certain patients with pulmonary sulcus NSCLC. Either chemotherapy or radiotherapy is administered first and, if there is no apparent deterioration of the patient's general condition, the next treatment modality is administered.

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1	Glassman LR and Hyman K: Pancoast tumor: A modern perspective on an old problem. Curr Opin Pulm Med. 19:340–343. 2013. View Article : Google Scholar : PubMed/NCBI
2	Peedell C, Dunning J and Bapusamy A: Is there a standard of care for the radical management of non-small cell lung cancer involving the apical chest wall (Pancoast tumours)? Clin Oncol (R Coll Radiol). 22:334–346. 2010. View Article : Google Scholar : PubMed/NCBI
3	Laine AM, Westover KD and Choy H: Radiation therapy as a backbone of treatment of locally advanced non-small cell lung cancer. Semin Oncol. 41:57–68. 2014. View Article : Google Scholar : PubMed/NCBI
4	Antoni D and Mornex F: Chemoradiotherapy of locally advanced nonsmall cell lung cancer: State of the art and perspectives. Curr Opin Oncol. 28:104–109. 2016. View Article : Google Scholar : PubMed/NCBI
5	Xu P and Le Pechoux C: Chemoradiotherapy for stage III non-small cell lung cancer: Have we reached the limit? Chin Clin Oncol. 4:452015.PubMed/NCBI
6	Topkan E, Yildirim BA, Guler OC, Parlak C, Pehlivan B and Selek U: Safety and palliative efficacy of single-dose 8-Gy reirradiation for painful local failure in patients with stage IV non-small cell lung cancer previously treated with radical chemoradiation therapy. Int J Radiat Oncol Biol Phys. 91:774–780. 2015. View Article : Google Scholar : PubMed/NCBI
7	Dandekar VK, Young J, Kiel K, Bonomi P, Fidler MJ, Batus M and Sher DJ: Efficacy and tolerability of palliative split-course thoracic chemoradiotherapy for symptomatic Non-small cell lung cancer. Am J Clin Oncol. 38:605–609. 2015. View Article : Google Scholar : PubMed/NCBI
8	Sculier JP and Moro-Sibilot D: First- and second-line therapy for advanced nonsmall cell lung cancer. Eur Respir J. 33:915–930. 2009. View Article : Google Scholar : PubMed/NCBI
9	Bareschino MA, Schettino C, Rossi A, Maione P, Sacco PC, Zeppa R and Gridelli C: Treatment of advanced non small cell lung cancer. J Thorac Dis. 3:122–133. 2011.PubMed/NCBI
10	Thomas A, Liu SV, Subramaniam DS and Giaccone G: Refining the treatment of NSCLC according to histological and molecular subtypes. Nat Rev Clin Oncol. 12:511–526. 2015. View Article : Google Scholar : PubMed/NCBI
11	Gerber DE, Gandhi L and Costa DB: Management and future directions in non-small cell lung cancer with known activating mutations. Am Soc Clin Oncol Educ Book. e353–e365. 2014. View Article : Google Scholar : PubMed/NCBI

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Palliative sequential chemoradiotherapy for pulmonary sulcus tumor: A case report

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Abstract

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