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Article

Comparison of mammography and ultrasound in detecting residual disease following bioptic lumpectomy in breast cancer patients

  • Authors:
    • Xiufeng Wu
    • Qingzhong Lin
    • Jianping Lu
    • Gang Chen
    • Yi Zeng
    • Yinglan Lin
    • Ying Chen
    • Yaoqin Wang
    • Jun Yan
  • View Affiliations / Copyright

    Affiliations: Department of Surgery, Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou, Fujian 350014, P.R. China, Department of Pathology, Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou, Fujian 350014, P.R. China, Department of Radiology, Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou, Fujian 350014, P.R. China, Department of Ultrasound, Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou, Fujian 350014, P.R. China, Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China
  • Pages: 419-424
    |
    Published online on: January 14, 2016
       https://doi.org/10.3892/mco.2016.729
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Abstract

Surgical biopsy is a method for diagnosing breast cancer. The aim of this study was to prospectively evaluate the relative accuracies of mammography (MMG) and ultrasound (US) in predicting residual disease following bioptic lumpectomy. Each prediction method was compared with the gold standard of surgical pathology. The results of MMG and US from 312 consecutive breast cancer patients diagnosed by surgical excision were analyzed. All the patients underwent re‑excision mastectomy or lumpectomy and the imaging results were compared with the histopathological findings. The accuracy and sensitivity of each modality were investigated. A total of 312 patients with 312 primary breast cancers were investigated. Residual disease was identified in 118 patients. Of the 118 cases with residual disease, MMG and US were able to detect 77 (65.3%) and 32 (27.1%), respectively (chi‑square P<0.001). MMG was also more sensitive compared with US in estimating residual ductal carcinoma in situ (DCIS) (94.2 vs. 33.3%, respectively; P<0.001). MMG was more accurate compared with US in detecting residual disease following bioptic lumpectomy and the diagnostic accuracy of MMG was associated with the presence of residual DCIS.
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Copy and paste a formatted citation
Spandidos Publications style
Wu X, Lin Q, Lu J, Chen G, Zeng Y, Lin Y, Chen Y, Wang Y and Yan J: Comparison of mammography and ultrasound in detecting residual disease following bioptic lumpectomy in breast cancer patients. Mol Clin Oncol 4: 419-424, 2016.
APA
Wu, X., Lin, Q., Lu, J., Chen, G., Zeng, Y., Lin, Y. ... Yan, J. (2016). Comparison of mammography and ultrasound in detecting residual disease following bioptic lumpectomy in breast cancer patients. Molecular and Clinical Oncology, 4, 419-424. https://doi.org/10.3892/mco.2016.729
MLA
Wu, X., Lin, Q., Lu, J., Chen, G., Zeng, Y., Lin, Y., Chen, Y., Wang, Y., Yan, J."Comparison of mammography and ultrasound in detecting residual disease following bioptic lumpectomy in breast cancer patients". Molecular and Clinical Oncology 4.3 (2016): 419-424.
Chicago
Wu, X., Lin, Q., Lu, J., Chen, G., Zeng, Y., Lin, Y., Chen, Y., Wang, Y., Yan, J."Comparison of mammography and ultrasound in detecting residual disease following bioptic lumpectomy in breast cancer patients". Molecular and Clinical Oncology 4, no. 3 (2016): 419-424. https://doi.org/10.3892/mco.2016.729
Copy and paste a formatted citation
x
Spandidos Publications style
Wu X, Lin Q, Lu J, Chen G, Zeng Y, Lin Y, Chen Y, Wang Y and Yan J: Comparison of mammography and ultrasound in detecting residual disease following bioptic lumpectomy in breast cancer patients. Mol Clin Oncol 4: 419-424, 2016.
APA
Wu, X., Lin, Q., Lu, J., Chen, G., Zeng, Y., Lin, Y. ... Yan, J. (2016). Comparison of mammography and ultrasound in detecting residual disease following bioptic lumpectomy in breast cancer patients. Molecular and Clinical Oncology, 4, 419-424. https://doi.org/10.3892/mco.2016.729
MLA
Wu, X., Lin, Q., Lu, J., Chen, G., Zeng, Y., Lin, Y., Chen, Y., Wang, Y., Yan, J."Comparison of mammography and ultrasound in detecting residual disease following bioptic lumpectomy in breast cancer patients". Molecular and Clinical Oncology 4.3 (2016): 419-424.
Chicago
Wu, X., Lin, Q., Lu, J., Chen, G., Zeng, Y., Lin, Y., Chen, Y., Wang, Y., Yan, J."Comparison of mammography and ultrasound in detecting residual disease following bioptic lumpectomy in breast cancer patients". Molecular and Clinical Oncology 4, no. 3 (2016): 419-424. https://doi.org/10.3892/mco.2016.729
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