Fibroepithelioma of Pinkus: Solitary tumor or sign of a complex gastrointestinal syndrome

Longo,Caterina; Pellacani,Giovanni; Tomasi,Aldo; Mandel,Victor  Desmond; Ponti,Giovanni

doi:10.3892/mco.2016.794

May-2016 Volume 4 Issue 5

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May-2016 Volume 4 Issue 5

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Article

Fibroepithelioma of Pinkus: Solitary tumor or sign of a complex gastrointestinal syndrome

Authors:
- Caterina Longo
- Giovanni Pellacani
- Aldo Tomasi
- Victor Desmond Mandel
- Giovanni Ponti
View Affiliations / Copyright

Affiliations: Dermatology and Skin Cancer Unit, Arcispedale Santa Maria Nuova‑IRCCS, I‑42123 Reggio Emilia, Italy, Department of Dermatology, University of Modena and Reggio Emilia, I‑41100 Modena, Italy, Department of Clinical and Diagnostic Medicine and Public Health, University of Modena and Reggio Emilia, I‑41100 Modena, Italy
Pages: 797-800
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Published online on: February 26, 2016

https://doi.org/10.3892/mco.2016.794
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Abstract

Fibroepithelioma of Pinkus (FEP), which is considered to be an uncommon variant of basal cell carcinoma, has been described in association with other systemic diseases. However, no specific studies are currently available on this subject. The aim of our study was to evaluate the clinical and morphological characteristics of FEP and investigate whether this rare tumor is a single entity or seen in the context of a more complex syndrome. We retrospectively analyzed 49 cases of FEP diagnosed and excised in a single academic institution from 1995 to 2011. The tumors were mainly located on the trunk (77.55%), followed by the lower extremities (12.20%) and the head and neck (10.20%). In 9 of the 49 cases (18%), FEP was associated with gastrointestinal tumors. The abovementioned cases are presented in an attempt to make clinicians more aware of a possible association between FEP and gastrointestinal cancer. Although a possible underlying common genetic background between FEP and gastrointestinal tumors was not provided, our study suggests that patients with FEP should be screened for the occurrence of gastrointestinal tumors.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Fibroepithelioma of Pinkus: Solitary tumor or sign of a complex gastrointestinal syndrome

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