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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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May-2016 Volume 4 Issue 5

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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International Journal of Epigenetics

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Case Report

Repeated changes of the molecular subtype in gastric metastasis from breast cancer: A case report

  • Authors:
    • Jun Nakamura
    • Keiichiro Okuyama
    • Hirofumi Sato
    • Yukie Yoda
    • Keita Kai
    • Hirokazu Noshiro
  • View Affiliations / Copyright

    Affiliations: Department of Surgery, Saga University Faculty of Medicine, Saga 849‑8501, Japan, Department of Pathology, Saga University Hospital, Saga 849‑8501, Japan
  • Pages: 695-698
    |
    Published online on: March 1, 2016
       https://doi.org/10.3892/mco.2016.795
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Abstract

Gastric metastasis from breast cancer is clinically diagnosed rarely. The present study described an interesting and valuable case of gastric metastasis from breast cancer, which showed repeated changes of the molecular subtype with an impact on the choice of treatment. A 42‑year‑old woman underwent mastectomy with axillary lymph node dissection for an invasive lobular carcinoma of the left breast. The patient received gastroscopy due to an epigastric pain during the adjuvant chemotherapy. The endoscopic examination revealed an erosive lesion at the posterior wall of the gastric body. The gastric lesion was immunohistochemically diagnosed as a metastatic disease from the breast cancer. The patient initially received hormone therapy, according to the subtype of the primary and the metastatic diseases. The gastric lesion initially disappeared; however, a relapsed lesion transformed into luminal human epidermal growth factor receptor 2 type from luminal type. Subsequently, the metastatic lesions underwent repeated subtype changing, which created difficultly when deciding the treatment strategy. The molecular profile of breast cancer can change during the treatment, resulting in the treatment resistance observed in certain cases. Therefore, the optimal treatment must be selected, according to the changed subtype.
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Copy and paste a formatted citation
Spandidos Publications style
Nakamura J, Okuyama K, Sato H, Yoda Y, Kai K and Noshiro H: Repeated changes of the molecular subtype in gastric metastasis from breast cancer: A case report. Mol Clin Oncol 4: 695-698, 2016.
APA
Nakamura, J., Okuyama, K., Sato, H., Yoda, Y., Kai, K., & Noshiro, H. (2016). Repeated changes of the molecular subtype in gastric metastasis from breast cancer: A case report. Molecular and Clinical Oncology, 4, 695-698. https://doi.org/10.3892/mco.2016.795
MLA
Nakamura, J., Okuyama, K., Sato, H., Yoda, Y., Kai, K., Noshiro, H."Repeated changes of the molecular subtype in gastric metastasis from breast cancer: A case report". Molecular and Clinical Oncology 4.5 (2016): 695-698.
Chicago
Nakamura, J., Okuyama, K., Sato, H., Yoda, Y., Kai, K., Noshiro, H."Repeated changes of the molecular subtype in gastric metastasis from breast cancer: A case report". Molecular and Clinical Oncology 4, no. 5 (2016): 695-698. https://doi.org/10.3892/mco.2016.795
Copy and paste a formatted citation
x
Spandidos Publications style
Nakamura J, Okuyama K, Sato H, Yoda Y, Kai K and Noshiro H: Repeated changes of the molecular subtype in gastric metastasis from breast cancer: A case report. Mol Clin Oncol 4: 695-698, 2016.
APA
Nakamura, J., Okuyama, K., Sato, H., Yoda, Y., Kai, K., & Noshiro, H. (2016). Repeated changes of the molecular subtype in gastric metastasis from breast cancer: A case report. Molecular and Clinical Oncology, 4, 695-698. https://doi.org/10.3892/mco.2016.795
MLA
Nakamura, J., Okuyama, K., Sato, H., Yoda, Y., Kai, K., Noshiro, H."Repeated changes of the molecular subtype in gastric metastasis from breast cancer: A case report". Molecular and Clinical Oncology 4.5 (2016): 695-698.
Chicago
Nakamura, J., Okuyama, K., Sato, H., Yoda, Y., Kai, K., Noshiro, H."Repeated changes of the molecular subtype in gastric metastasis from breast cancer: A case report". Molecular and Clinical Oncology 4, no. 5 (2016): 695-698. https://doi.org/10.3892/mco.2016.795
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