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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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Case Report

Comprehensive treatment of unresectable cardiac angiosarcoma: A case report and review of literature

  • Authors:
    • Chao Wang
    • Min Shi
    • Chen Yang
    • Tao Ma
    • Jinling Jiang
    • Ying Liu
    • Wenqi Xi
    • Zhenggang Zhu
    • Jun Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, P.R. China
  • Pages: 859-863
    |
    Published online on: August 24, 2017
       https://doi.org/10.3892/mco.2017.1390
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Abstract

Cardiac angiosarcoma is a rare but lethal tumor that is difficult to diagnose and treat, due to its rapid local relapse and high incidence of systemic metastasis. The prognosis of cardiac angiosarcoma is dismal, with a mean life expectancy of only a few months. We herein report a case of unresectable angiosarcoma arising from the right atrium. The patient received first‑line chemotherapy with weekly paclitaxel, and second‑line therapy with vinorelbine and bevacizumab upon disease progression. The progression‑free survival was 6 months and the overall survival was 7 months. The patient eventually succumbed to respiratory failure. A study of the present case and a review of the relevant literature suggest that treatment decisions for unresectable locally advanced or metastatic cardiac angiosarcoma are difficult, as the published literature on this disease mainly consists of case reports without sufficient data. Therefore, further clinical trials specific to the treatment of unresectable cardiac angiosarcoma are warranted.
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Copy and paste a formatted citation
Spandidos Publications style
Wang C, Shi M, Yang C, Ma T, Jiang J, Liu Y, Xi W, Zhu Z and Zhang J: Comprehensive treatment of unresectable cardiac angiosarcoma: A case report and review of literature. Mol Clin Oncol 7: 859-863, 2017.
APA
Wang, C., Shi, M., Yang, C., Ma, T., Jiang, J., Liu, Y. ... Zhang, J. (2017). Comprehensive treatment of unresectable cardiac angiosarcoma: A case report and review of literature. Molecular and Clinical Oncology, 7, 859-863. https://doi.org/10.3892/mco.2017.1390
MLA
Wang, C., Shi, M., Yang, C., Ma, T., Jiang, J., Liu, Y., Xi, W., Zhu, Z., Zhang, J."Comprehensive treatment of unresectable cardiac angiosarcoma: A case report and review of literature". Molecular and Clinical Oncology 7.5 (2017): 859-863.
Chicago
Wang, C., Shi, M., Yang, C., Ma, T., Jiang, J., Liu, Y., Xi, W., Zhu, Z., Zhang, J."Comprehensive treatment of unresectable cardiac angiosarcoma: A case report and review of literature". Molecular and Clinical Oncology 7, no. 5 (2017): 859-863. https://doi.org/10.3892/mco.2017.1390
Copy and paste a formatted citation
x
Spandidos Publications style
Wang C, Shi M, Yang C, Ma T, Jiang J, Liu Y, Xi W, Zhu Z and Zhang J: Comprehensive treatment of unresectable cardiac angiosarcoma: A case report and review of literature. Mol Clin Oncol 7: 859-863, 2017.
APA
Wang, C., Shi, M., Yang, C., Ma, T., Jiang, J., Liu, Y. ... Zhang, J. (2017). Comprehensive treatment of unresectable cardiac angiosarcoma: A case report and review of literature. Molecular and Clinical Oncology, 7, 859-863. https://doi.org/10.3892/mco.2017.1390
MLA
Wang, C., Shi, M., Yang, C., Ma, T., Jiang, J., Liu, Y., Xi, W., Zhu, Z., Zhang, J."Comprehensive treatment of unresectable cardiac angiosarcoma: A case report and review of literature". Molecular and Clinical Oncology 7.5 (2017): 859-863.
Chicago
Wang, C., Shi, M., Yang, C., Ma, T., Jiang, J., Liu, Y., Xi, W., Zhu, Z., Zhang, J."Comprehensive treatment of unresectable cardiac angiosarcoma: A case report and review of literature". Molecular and Clinical Oncology 7, no. 5 (2017): 859-863. https://doi.org/10.3892/mco.2017.1390
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