Radiation‑induced angiosarcoma of the omentum diagnosed by laparoscopy: A case report

Kunitomi,Haruko; Banno,Kouji; Iseki,Hayato; Sera,Asako; Miyauchi,Azumi; Kobayashi,Yusuke; Hayashi,Shigenori; Tominaga,Eiichiro; Sasaki,Aya; Kawaida,Miho; Kameyama,Kaori; Aoki,Daisuke

doi:10.3892/mco.2017.1513

February-2018 Volume 8 Issue 2

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February-2018 Volume 8 Issue 2

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Case Report Open Access

Radiation‑induced angiosarcoma of the omentum diagnosed by laparoscopy: A case report

Authors:
- Haruko Kunitomi
- Kouji Banno
- Hayato Iseki
- Asako Sera
- Azumi Miyauchi
- Yusuke Kobayashi
- Shigenori Hayashi
- Eiichiro Tominaga
- Aya Sasaki
- Miho Kawaida
- Kaori Kameyama
- Daisuke Aoki
View Affiliations / Copyright

Affiliations: Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo 160‑8582, Japan, Division of Diagnostic Pathology, Keio University School of Medicine, Tokyo 160‑8582, Japan

Copyright: © Kunitomi et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 264-268
|
Published online on: November 27, 2017

https://doi.org/10.3892/mco.2017.1513
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Abstract

Angiosarcoma is a rare malignant tumor with an aggressive clinical course and a poor prognosis. Intraperitoneal angiosarcoma, especially originating from the omentum, is extremely rare. We report a case of radiation‑induced angiosarcoma of the omentum that arose in a 38‑year‑old female seven years after concurrent chemoradiotherapy for cervical cancer. The primary tumor was unknown until diagnostic laparoscopy revealed an unresectable omental mass. Pathological examination revealed high‑grade malignant cells positive for endothelial markers. Although the small number of cases limits the consensus on optimal therapy for advanced angiosarcoma, the patient was managed successfully by taxane‑based chemotherapy, leading to complete response and consequent complete cytoreductive surgery. Our report is the fifth case of radiation‑induced angiosarcoma of the omentum, and all have developed after treatment for gynecologic cancer. Although very rare, this complication should be considered after radiation therapy in cancer treatment, particularly given the increasing importance of this therapy.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Radiation‑induced angiosarcoma of the omentum diagnosed by laparoscopy: A case report

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Abstract

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