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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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March-2018 Volume 8 Issue 3

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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Case Report

Oxaliplatin-induced hepatic sinusoidal obstruction syndrome in a patient with gastric cancer: A case report

  • Authors:
    • Fang Liu
    • Xin Cao
    • Jin Ye
    • Xiaoli Pan
    • Xuefeng Kan
    • Yuhu Song
  • View Affiliations / Copyright

    Affiliations: Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China, Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China, Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China
  • Pages: 453-456
    |
    Published online on: December 18, 2017
       https://doi.org/10.3892/mco.2017.1540
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Abstract

Oxaliplatin is a platinum-based antineoplastic agent used in cancer chemotherapy. Oxaliplatin-induced hepatic sinusoidal obstruction syndrome (HSOS) has been reported in the context of chemotherapy for liver metastasis of colorectal cancer. However, to the best of our knowledge, there is no report of oxaliplatin‑associated HSOS in patients with gastric cancer. The present study reported a patient with gastric cancer who received proximal gastrectomy and oxaliplatin‑containing chemotherapy. Contrast‑enhanced computed tomography revealed that liver parenchyma appeared heterogeneous and demonstrated hypoattenuation in the portal phase. In dynamic contrast‑enhanced magnetic resonance imaging, hypointense heterogeneity was demonstrated in the portal‑venous phase. Pathological examination indicated distinctive multifocal sinusoidal dilatation. In conclusion, the present report indicated a case of oxaliplatin‑induced HSOS in a patient with gastric cancer who received oxaliplatin-contained chemotherapy.
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Copy and paste a formatted citation
Spandidos Publications style
Liu F, Cao X, Ye J, Pan X, Kan X and Song Y: Oxaliplatin-induced hepatic sinusoidal obstruction syndrome in a patient with gastric cancer: A case report. Mol Clin Oncol 8: 453-456, 2018.
APA
Liu, F., Cao, X., Ye, J., Pan, X., Kan, X., & Song, Y. (2018). Oxaliplatin-induced hepatic sinusoidal obstruction syndrome in a patient with gastric cancer: A case report. Molecular and Clinical Oncology, 8, 453-456. https://doi.org/10.3892/mco.2017.1540
MLA
Liu, F., Cao, X., Ye, J., Pan, X., Kan, X., Song, Y."Oxaliplatin-induced hepatic sinusoidal obstruction syndrome in a patient with gastric cancer: A case report". Molecular and Clinical Oncology 8.3 (2018): 453-456.
Chicago
Liu, F., Cao, X., Ye, J., Pan, X., Kan, X., Song, Y."Oxaliplatin-induced hepatic sinusoidal obstruction syndrome in a patient with gastric cancer: A case report". Molecular and Clinical Oncology 8, no. 3 (2018): 453-456. https://doi.org/10.3892/mco.2017.1540
Copy and paste a formatted citation
x
Spandidos Publications style
Liu F, Cao X, Ye J, Pan X, Kan X and Song Y: Oxaliplatin-induced hepatic sinusoidal obstruction syndrome in a patient with gastric cancer: A case report. Mol Clin Oncol 8: 453-456, 2018.
APA
Liu, F., Cao, X., Ye, J., Pan, X., Kan, X., & Song, Y. (2018). Oxaliplatin-induced hepatic sinusoidal obstruction syndrome in a patient with gastric cancer: A case report. Molecular and Clinical Oncology, 8, 453-456. https://doi.org/10.3892/mco.2017.1540
MLA
Liu, F., Cao, X., Ye, J., Pan, X., Kan, X., Song, Y."Oxaliplatin-induced hepatic sinusoidal obstruction syndrome in a patient with gastric cancer: A case report". Molecular and Clinical Oncology 8.3 (2018): 453-456.
Chicago
Liu, F., Cao, X., Ye, J., Pan, X., Kan, X., Song, Y."Oxaliplatin-induced hepatic sinusoidal obstruction syndrome in a patient with gastric cancer: A case report". Molecular and Clinical Oncology 8, no. 3 (2018): 453-456. https://doi.org/10.3892/mco.2017.1540
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