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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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April-2018 Volume 8 Issue 4

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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Case Report

Intramedullary melanotic schwannoma of the cervical spine: A case report and literature review

  • Authors:
    • Ling Hu
    • Chao Wang
  • View Affiliations / Copyright

    Affiliations: Department of Ultrasound, Hangzhou Women's Hospital, Hangzhou, Zhejiang 310016, P.R. China, Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, P.R. China
  • Pages: 567-570
    |
    Published online on: February 27, 2018
       https://doi.org/10.3892/mco.2018.1584
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Abstract

Intramedullary melanotic schwannomas (IMS) are rare lesions, with only 8 cases reported in the literature to date. We herein describe the case of a 40‑year‑old male patient with an IMS of the cervical cord, which, to the best of our knowledge, is the ninth reported case of IMS, and review the relevant literature. The patient presented with numbness of the left arm that gradually worsened over a period of 4 months. Magnetic resonance imaging (MRI) of the cervical spine with gadolinium enhancement revealed an intramedullary lesion at the level of C1‑C2. The mass was T1 hyperintense, T2 hypointense and homogeneously enhanced. During surgery, an intramedullary dark gray lesion was identified and was partially removed. The left arm numbness partially subsided 2 weeks after surgery. Although rare, IMS is associated with characteristic MRI findings (T1 hyperintensity, T2 hypointensity and homogeneous enhancement) and MRI is the preferred method for evaluating lesions of the spinal cord. Correct diagnosis is crucial for management planning; therefore, immunohistochemical examination is required. In addition, IMS cases must be closely followed up, particularly when the mass cannot be completely resected.
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Copy and paste a formatted citation
Spandidos Publications style
Hu L and Wang C: Intramedullary melanotic schwannoma of the cervical spine: A case report and literature review. Mol Clin Oncol 8: 567-570, 2018.
APA
Hu, L., & Wang, C. (2018). Intramedullary melanotic schwannoma of the cervical spine: A case report and literature review. Molecular and Clinical Oncology, 8, 567-570. https://doi.org/10.3892/mco.2018.1584
MLA
Hu, L., Wang, C."Intramedullary melanotic schwannoma of the cervical spine: A case report and literature review". Molecular and Clinical Oncology 8.4 (2018): 567-570.
Chicago
Hu, L., Wang, C."Intramedullary melanotic schwannoma of the cervical spine: A case report and literature review". Molecular and Clinical Oncology 8, no. 4 (2018): 567-570. https://doi.org/10.3892/mco.2018.1584
Copy and paste a formatted citation
x
Spandidos Publications style
Hu L and Wang C: Intramedullary melanotic schwannoma of the cervical spine: A case report and literature review. Mol Clin Oncol 8: 567-570, 2018.
APA
Hu, L., & Wang, C. (2018). Intramedullary melanotic schwannoma of the cervical spine: A case report and literature review. Molecular and Clinical Oncology, 8, 567-570. https://doi.org/10.3892/mco.2018.1584
MLA
Hu, L., Wang, C."Intramedullary melanotic schwannoma of the cervical spine: A case report and literature review". Molecular and Clinical Oncology 8.4 (2018): 567-570.
Chicago
Hu, L., Wang, C."Intramedullary melanotic schwannoma of the cervical spine: A case report and literature review". Molecular and Clinical Oncology 8, no. 4 (2018): 567-570. https://doi.org/10.3892/mco.2018.1584
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