Red nodular melanoma of the penile foreskin: A case report and literature review

Maruyama,Yuki; Sadahira,Takuya; Mitsui,Yosuke; Wada,Koichiro; Tanimoto,Ryuta; Kobayashi,Yasuyuki; Araki,Motoo; Watanabe,Masami; Watanabe,Toyohiko; Nasu,Yasutomo

doi:10.3892/mco.2018.1697

Red nodular melanoma of the penile foreskin: A case report and literature review

Authors:
- Yuki Maruyama
- Takuya Sadahira
- Yosuke Mitsui
- Koichiro Wada
- Ryuta Tanimoto
- Yasuyuki Kobayashi
- Motoo Araki
- Masami Watanabe
- Toyohiko Watanabe
- Yasutomo Nasu
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Affiliations: Department of Urology, Okayama University Graduate School of Medicine, Okayama, Okayama 700‑8558, Japan
Published online on: August 13, 2018 https://doi.org/10.3892/mco.2018.1697
Pages: 449-452

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Abstract

The penis is an extremely rare primary site for malignant melanomas, and the clinical presentation may vary greatly. We herein present the case of a 71‑year‑old male patient who presented with a 6‑year history of two slow growing, asymptomatic red macules on the penile foreskin. On physical examination, the mobility of the foreskin was good, and there was no metastasis on computed tomography and magnetic resonance imaging. The patient underwent segmental circumcision for treatment and histological diagnosis, and the histological examination revealed a malignant melanoma. As cancer cells were identified at the edge of the tissue specimen and computed tomography‑positron emission tomography revealed increased uptake of 18F‑fluorodeoxyglucose in the penis, wider resection and a right sentinel lymph node biopsy were performed; both specimens came back negative. Two years after the surgery, there has been no evidence of locoregional recurrence or distant metastases. The aim of this report is to alert physicians to include melanoma in the differential diagnosis of red‑pigmented lesions of the penile foreskin.

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