|
1
|
El-Serag HB: Hepatocellular carcinoma. N
Engl J Med. 365:1118–1127. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Villanueva A and Llovet JM: Liver cancer
in 2013: Mutational landscape of HCC-the end of the beginning. Nat
Rev Clin Oncol. 11:73–74. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Ferlay J, Soerjomataram I, Dikshit R, Eser
S, Mathers C, Rebelo M, Parkin DM, Forman D and Bray F: Cancer
incidence and mortality worldwide: Sources, methods and major
patterns in GLOBOCAN. Int J Cancer. 136:E359–E386. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Shi YX, Zhu T, Zou T, Zhuo W, Chen YX,
Huang MS, Zheng W, Wang CJ, Li X, Mao XY, et al: Prognostic and
predictive values of CDK1 and MAD2L1 in lung adenocarcinoma.
Oncotarget. 7:85235–85243. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Liang B, Li C and Zhao J: Identification
of key pathways and genes in colorectal cancer using bioinformatics
analysis. Med Oncol. 33:1112016. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Lee JS and Thorgeirsson SS: Comparative
and integrative functional genomics of HCC. Oncogene. 25:3801–3809.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Ho DW, Kai AK and Ng IO: TCGA
whole-transcriptome sequencing data reveals significantly
dysregulated genes and signaling pathways in hepatocellular
carcinoma. Front Med. 9:322–330. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Huang Q, Lin B, Liu H, Ma X, Mo F, Yu W,
Li L, Li H, Tian T, Wu D, et al: RNA-Seq analyses generate
comprehensive transcriptomic landscape and reveal complex
transcript patterns in hepatocellular carcinoma. PLoS One.
6:e261682011. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Lin KT, Shann YJ, Chau GY, Hsu CN and
Huang CY: Identification of latent biomarkers in hepatocellular
carcinoma by ultra-deep whole-transcriptome sequencing. Oncogene.
33:4786–4794. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Roessler S, Jia HL, Budhu A, Forgues M, Ye
QH, Lee JS, Thorgeirsson SS, Sun Z, Tang ZY, Qin LX and Wang XW: A
unique metastasis gene signature enables prediction of tumor
relapse in early-stage hepatocellular carcinoma patients. Cancer
Res. 70:10202–10212. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Roessler S, Long EL, Budhu A, Chen Y, Zhao
X, Ji J, Walker R, Jia HL, Ye QH, Qin LX, et al: Integrative
genomic identification of genes on 8p associated with
hepatocellular carcinoma progression and patient survival.
Gastroenterology. 142:957–966, e12. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Robinson MD, McCarthy DJ and Smyth GK:
edgeR: A Bioconductor package for differential expression analysis
of digital gene expression data. Bioinformatics. 26:139–140. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Gene Ontology Consortium: The Gene
Ontology (GO) project in 2006. Nucleic Acids Res. 34(Database
Issue): D322–D326. 2006.PubMed/NCBI
|
|
14
|
Kanehisa M and Goto S: KEGG: Kyoto
encyclopedia of genes and genomes. Nucleic Acids Res. 28:27–30.
2000. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
da Huang W, Sherman BT and Lempicki RA:
Systematic and integrative analysis of large gene lists using DAVID
bioinformatics resources. Nat Protoc. 4:44–57. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Szklarczyk D, Franceschini A, Wyder S,
Forslund K, Heller D, Huerta-Cepas J, Simonovic M, Roth A, Santos
A, Tsafou KP, et al: STRING v10: Protein-protein interaction
networks, integrated over the tree of life. Nucleic Acids Res.
43:(Database Issue). D447–D452. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Gentleman RC, Carey VJ, Bates DM, Bolstad
B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, et al:
Bioconductor: Open software development for computational biology
and bioinformatics. Genome Biol. 5:R802004. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Hong G, Zhang W, Li H, Shen X and Guo Z:
Separate enrichment analysis of pathways for up- and downregulated
genes. J R Soc Interface. 11:201309502013. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Chen P, Zheng X, Zhou Y, Xu Y, Zhu L and
Qian Y: Talin-1 interaction network promotes hepatocellular
carcinoma progression. Oncotarget. 8:13003–13014. 2017.PubMed/NCBI
|
|
20
|
Sun H, Peng Z, Tang H, Xie D, Jia Z, Zhong
L, Zhao S, Ma Z, Gao Y, Zeng L, et al: Loss of KLF4 and
consequential downregulation of Smad7 exacerbate oncogenic TGF-β
signaling in and promote progression of hepatocellular carcinoma.
Oncogene. 36:2957–2968. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Ko JH, Ko EA, Gu W, Lim I, Bang H and Zhou
T: Expression profiling of ion channel genes predicts clinical
outcome in breast cancer. Mol Cancer. 12:1062013. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Kulkarni A, Natarajan SK, Chandrasekar V,
Pandey PR and Sengupta S: Combining immune checkpoint inhibitors
and kinase-inhibiting supramolecular therapeutics for enhanced
anticancer efficacy. Acs Nano. 2016. View Article : Google Scholar
|
|
23
|
Hughes PE, Caenepeel S and Wu LC: Targeted
therapy and checkpoint immunotherapy combinations for the treatment
of cancer. Trends Immunol. 37:462–476. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Hanahan D and Weinberg RA: The hallmarks
of cancer. Cell. 100:57–70. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Hanahan D and Weinberg RA: Hallmarks of
cancer: The next generation. Cell. 144:646–674. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Dominguez-Brauer C, Thu KL, Mason JM,
Blaser H, Bray MR and Mak TW: Targeting mitosis in cancer: Emerging
strategies. Mol Cell. 60:524–536. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Visconti R, Della Monica R and Grieco D:
Cell cycle checkpoint in cancer: A therapeutically targetable
double-edged sword. J Exp Clin Cancer Res. 35:1532016. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Cai H, Li H, Li J, Li X, Li Y, Shi Y and
Wang D: Sonic hedgehog signaling pathway mediates development of
hepatocellular carcinoma. Tumour Biol. 2016. View Article : Google Scholar
|
|
29
|
Jin B, Wang W, Du G, Huang GZ, Han LT,
Tang ZY, Fan DG, Li J and Zhang SZ: Identifying hub genes and
dysregulated pathways in hepatocellular carcinoma. Eur Rev Med
Pharmacol Sci. 19:592–601. 2015.PubMed/NCBI
|
|
30
|
Bertoli C, Skotheim JM and de Bruin RA:
Control of cell cycle transcription during G1 and S phases. Nat Rev
Mol Cell Biol. 14:518–528. 2013. View
Article : Google Scholar : PubMed/NCBI
|
|
31
|
Fang Y, Yu H, Liang X, Xu J and Cai X:
Chk1-induced CCNB1 overexpression promotes cell proliferation and
tumor growth in human colorectal cancer. Cancer Biol Ther.
15:1268–1279. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Ding K, Li W, Zou Z, Zou X and Wang C:
CCNB1 is a prognostic biomarker for ER+ breast cancer. Med
Hypotheses. 83:359–364. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Diab A, Foca A, Fusil F, Lahlali T,
Jalaguier P, Amirache F, N'Guyen L, Isorce N, Cosset FL, Zoulim F,
et al: Polo-like-kinase 1 is a proviral host factor for hepatitis B
virus replication. Hepatology. 66:1750–1765. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Li J, Wang R, Gannon OJ, Rezey AC, Jiang
S, Gerlach BD, Liao G and Tang DD: Polo-like Kinase 1 regulates
vimentin phosphorylation at ser-56 and contraction in smooth
muscle. J Biol Chem. 291:23693–23703. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Ruf S, Heberle AM, Langelaar-Makkinje M,
Gelino S, Wilkinson D, Gerbeth C, Schwarz JJ, Holzwarth B,
Warscheid B, Meisinger C, et al: PLK1 (polo like kinase 1) inhibits
MTOR complex 1 and promotes autophagy. Autophagy. 13:486–505. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Slamon DJ and Press MF: Alterations in the
TOP2A and HER2 genes: Association with adjuvant anthracycline
sensitivity in human breast cancers. J Natl Cancer Inst.
101:615–618. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Brase JC, Schmidt M, Fischbach T, Sültmann
H, Bojar H, Koelbl H, Hellwig B, Rahnenführer J, Hengstler JG and
Gehrmann MC: ERBB2 and TOP2A in breast cancer: A comprehensive
analysis of gene amplification, RNA levels, and protein expression
and their influence on prognosis and prediction. Clin Cancer Res.
16:2391–2401. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
de Los Fayos Alonso Garces I, Liang HC,
Turner SD, Lagger S, Merkel O and Kenner L: The role of activator
protein-1 (AP-1) family members in cd30-positive lymphomas. Cancers
(Basel). 10:pii: E932018. View Article : Google Scholar
|
|
39
|
Carmena M and Earnshaw WC: The cellular
geography of aurora kinases. Nat Rev Mol Cell Biol. 4:842–854.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Kapanidou M, Curtis NL and Bolanos-Garcia
VM: Cdc20: At the crossroads between chromosome segregation and
mitotic exit. Trends Biochem Sci. 42:193–205. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Hingorani P, Dickman P, Garcia-Filion P,
White-Collins A, Kolb EA and Azorsa DO: BIRC5 expression is a poor
prognostic marker in Ewing sarcoma. Pediatr Blood Cancer. 60:35–40.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Wang Q, Shu R, He H, Wang L, Ma Y, Zhu H,
Wang Z, Wang S, Shen G and Lei P: Co-silencing of Birc5 (survivin)
and Hspa5 (Grp78) induces apoptosis in hepatoma cells more
efficiently than single gene interference. Int J Oncol. 41:652–660.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Yang W, Cho H, Shin HY, Chung JY, Kang ES,
Lee EJ and Kim JH: Accumulation of cytoplasmic Cdk1 is associated
with cancer growth and survival rate in epithelial ovarian cancer.
Oncotarget. 7:49481–49497. 2016.PubMed/NCBI
|
|
44
|
Willder JM, Heng SJ, McCall P, Adams CE,
Tannahill C, Fyffe G, Seywright M, Horgan PG, Leung HY, Underwood
MA and Edwards J: Androgen receptor phosphorylation at serine 515
by Cdk1 predicts biochemical relapse in prostate cancer patients.
Br J Cancer. 108:139–148. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Sung WW, Lin YM, Wu PR, Yen HH, Lai HW, Su
TC, Huang RH, Wen CK, Chen CY, Chen CJ and Yeh KT: High
nuclear/cytoplasmic ratio of Cdk1 expression predicts poor
prognosis in colorectal cancer patients. BMC Cancer. 14:9512014.
View Article : Google Scholar : PubMed/NCBI
|
