Nasopharyngeal angiofibroma in an elderly female patient: A rare case report

Ralli,Massimo; Fusconi,Massimo; Visconti,Irene  Claudia; Martellucci,Salvatore; de Vincentiis,Marco; Greco,Antonio

doi:10.3892/mco.2018.1735

Nasopharyngeal angiofibroma in an elderly female patient: A rare case report

Authors:
- Massimo Ralli
- Massimo Fusconi
- Irene Claudia Visconti
- Salvatore Martellucci
- Marco de Vincentiis
- Antonio Greco
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Affiliations: Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, I‑00186 Rome, Italy, Department of Sense Organs, Sapienza University of Rome, I‑00186 Rome, Italy
Published online on: October 5, 2018 https://doi.org/10.3892/mco.2018.1735
Pages: 702-704

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Abstract

‘Juvenile’ nasopharyngeal angiofibroma, which accounts for <1% of all head and neck neoplasms, occurs predominantly in males between 10 and 18 years of age. The small number of patients older than 30 years confirms that presentation after this age is exceptional. Only rare cases of nasopharyngeal angiofibroma in female patients have been documented to date, and some authors believe that sex chromosome studies are indicated in such cases. The pathogenesis of nasopharyngeal angiofibroma remains unknown, but it has been hypothesized that it is a testosterone‑dependent tumor. We herein report a particularly rare case of a 68‑year‑old woman diagnosed with nasopharyngeal angiofibroma and describe the diagnostic and therapeutic workup. This case describes, to the best of our knowledge, the oldest patient reported in the literature.

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