Myxoid liposarcoma associated with adalimumab treatment: A case report

  • Authors:
    • Carmen Rodríguez-Cerdeira
    • José Ignacio Neissa-Vasquez
    • Miguel Carnero-Gregorio
    • Concepción Fiaño-Valverde
    • Victor Muñoz-Garzón
  • View Affiliations

  • Published online on: February 27, 2019     https://doi.org/10.3892/mco.2019.1817
  • Pages: 454-456
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Biological agents that suppress inflammation, such as tumour necrosis factor (TNF-α) inhibitors, are being successfully used at an increasing frequency for the treatment of chronic inflammatory diseases, such as psoriasis. However, these drugs are not free of side effects, and although the general rates of malignancy in patients using anti-TNF-α therapies are not high, certain tumours of cutaneous origin, particularly carcinomas, have been reported. We herein present the case of a 47-year-old female patient with moderate-to-severe psoriasis for 20 years under treatment with adalimumab administered at the standard dose of 40 mg, injected subcutaneously each fortnight, with good efficacy. To the best of our knowledge, this is the first reported case of a low-grade (grade 1) myxoid liposarcoma in a patient receiving treatment with adalimumab since 2009. A review of the relevant literature was also conducted. Continuous investigation of such cases is crucial in order to elucidate the iatrogenic risk of rare cancers, such as myxoid liposarcoma, in patients undergoing treatment with currently available as well as future biological therapies.
View Figures
View References

Related Articles

Journal Cover

April 2019
Volume 10 Issue 4

Print ISSN: 2049-9450
Online ISSN:2049-9469

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
APA
Rodríguez-Cerdeira, C., Neissa-Vasquez, J.I., Carnero-Gregorio, M., Fiaño-Valverde, C., & Muñoz-Garzón, V. (2019). Myxoid liposarcoma associated with adalimumab treatment: A case report. Molecular and Clinical Oncology, 10, 454-456. https://doi.org/10.3892/mco.2019.1817
MLA
Rodríguez-Cerdeira, C., Neissa-Vasquez, J. I., Carnero-Gregorio, M., Fiaño-Valverde, C., Muñoz-Garzón, V."Myxoid liposarcoma associated with adalimumab treatment: A case report". Molecular and Clinical Oncology 10.4 (2019): 454-456.
Chicago
Rodríguez-Cerdeira, C., Neissa-Vasquez, J. I., Carnero-Gregorio, M., Fiaño-Valverde, C., Muñoz-Garzón, V."Myxoid liposarcoma associated with adalimumab treatment: A case report". Molecular and Clinical Oncology 10, no. 4 (2019): 454-456. https://doi.org/10.3892/mco.2019.1817