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Article

Preoperative charcoal suspension tattoo for the detection of differentiated thyroid cancer recurrence

  • Authors:
    • Francesco Soprani
    • Andrea De Vito
    • Fabio Bondi
    • Giuseppe Magliulo
    • Soon Sue Rene
    • Caterina Cappi
    • Fabrizio Riganti
    • Claudio Vicini
    • Maurizio Puccetti
  • View Affiliations / Copyright

    Affiliations: Head and Neck Department, ENT Unit, Santa Maria delle Croci Hospital, Ravenna‑AUSL of Romagna, I‑48121 Ravenna, Italy, Head and Neck Department, ENT and Oral Surgery Unit, Morgagni‑Pierantoni Hospital, Forlì‑and‑Santa Maria delle Croci Hospital, Ravenna AUSL of Romagna, I‑47121 Forlì, Italy, Department of Endocrinology, Santa Maria delle Croci Hospital, AUSL of Romagna, I‑48121 Ravenna, Italy, Department of ‘Organi di Senso’, University ‘Sapienza’, I‑00161 Rome, Italy, Department of Otolaryngology Head and Neck Surgery, Ng Teng Fong General Hospital, Jurong Community Hospital, National University Health System, Singapore 648346, Republic of Singapore, Department of Pathology, Santa Maria delle Croci Hospital, AUSL of Romagna, I‑48121 Ravenna, Italy
  • Pages: 524-530
    |
    Published online on: March 15, 2019
       https://doi.org/10.3892/mco.2019.1826
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Abstract

Recurrent differentiated thyroid carcinoma can easily be detected by means of ultrasound (US) and thyroglobulin, and often requires further surgical intervention. Revision surgery is often a technical challenge with significant risk of complications, considering the altered anatomy, with a possibility of leaving behind residual neoplasm. Preoperative US‑guided tattooing localization has been introduced to reduce and prevent these potential problems during revision surgery. Encouraging results have been reported in the literature. Under US guidance, the lesion is identified and 0.5‑2 ml of colloidal charcoal is injected in its proximity using a 23 gauge needle. The extraction is accompanied by injection at constant pressure of charcoal in order to leave a trace of pigment along the path of the needle till the skin. From April 2008 to January 2016 we performed revision surgery in 27 patients for lymph‑nodes metastasis in differentiated thyroid cancer, using the technique of preoperative charcoal tattoo localization. Our previous study on the first group of 13 patients published in 2012, reported the preliminary results in terms of success rate and complications. The tolerance of charcoal injection was good for all patients and the procedure was demonstrated to be useful, contributing to the removal of metastatic lesion in 93% of procedures. We have registered minor surgical complications during revision in the central compartment of the neck: Transitory hypoparathyroidism in 2 cases (11%) and transitory vocal cord paresis in 3 cases (16%). Based on these results, preoperative charcoal tattoo localization in revision surgery of the neck for differentiated thyroid cancer recurrence can be considered a safe technique, easy to perform, with low‑costs and useful during surgical procedures, providing a significant reduction of iatrogenic damage and risks.
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1 

Schlumberger MJ: Papillary and follicular thyroid carcinoma. N Engl J Med. 338:297–306. 1998. View Article : Google Scholar : PubMed/NCBI

2 

Hartl DM, Chami L, Al Ghuzlan A, Leboulleux S, Baudin E, Schlumberger M and Travagli JP: Charcoal suspension tattoo localization for differentiated thyroid cancer recurrence. Ann Surg Oncol. 16:2602–2608. 2009. View Article : Google Scholar : PubMed/NCBI

3 

Kang TW, Shin JH, Han BK, Ko EY, Kang SS, Hahn SY, Kim JS and Oh YL: Preoperative ultrasound-guided tattooing localization of recurrences after thyroidectomy: Safety and effectiveness. Ann Surg Oncol. 16:1655–1659. 2009. View Article : Google Scholar : PubMed/NCBI

4 

Kim MK, Mandel SH, Baloch Z, Livolsi VA, Langer JE, Didonato L, Fish S and Weber RS: Morbidity following central compartment reoperation for recurrent or persistent thyroid cancer. Arch Otolaryngol Head Neck Surg. 130:1214–1216. 2004. View Article : Google Scholar : PubMed/NCBI

5 

Mathieu MC, Bonhomme-Faivre L, Rouzier R, Seiller M, Barreau-Pouhaer L and Travagli JP: Tattooing breast cancers treated with neoadjuvant chemotherapy. Ann Surg Oncol. 14:2233–2238. 2007. View Article : Google Scholar : PubMed/NCBI

6 

Chami L, Hartl D, Leboulleux S, Baudin E, Lumbroso J, Schlumberger M and Travagli JP: Preoperative localization of neck recurrences from thyroid cancer: Charcoal tattooing under ultrasound guidance. Thyroid. 25:341–346. 2015. View Article : Google Scholar : PubMed/NCBI

7 

Soprani F, Bondi F, Puccetti M and Armaroli V: Charcoal tattoo localization for differentiated thyroid cancer recurrence in the central compartment of the neck. Acta Otorhinolaryngol Ital. 32:87–92. 2012.PubMed/NCBI

8 

Wang Y, Lei K-R, He Y-P, Li XL, Ren WW, Zhao CK, Bo XW, Wang D, Sun CY and Xu HX: Malignancy risk stratification of thyroid nodules: Comparisons of four ultrasound Thyroid Imaging Reporting and Data Systems in surgically resected nodules. Sci Rep. 7:115602017. View Article : Google Scholar : PubMed/NCBI

9 

Bonhomme-Faivre L, Depraetere P, Savelli MP, Amdidouche D, Bizi E, Seiller M and Orbach-Arbouys S: Charcoal suspension for tumor labelling modifies macrophage activity in mice. Life Sci. 66:817–827. 2000. View Article : Google Scholar : PubMed/NCBI

10 

Biffoni M, Scipioni P and Macrina N: Surgical treatment of differentiated thyroid cancer recurrence. L'Endocrinologo. 10:143–148. 2009. View Article : Google Scholar

11 

Moley JF and Wells SA: Compartment-mediated dissection for papillary thyroid cancer. Langenbecks Arch Surg. 384:9–15. 1999. View Article : Google Scholar : PubMed/NCBI

12 

Lundgren CI, Hall P, Dickman PW and Zedenius J: Clinically significant prognostic factors for differentiated thyroid carcinoma: A population-based, nested case-control study. Cancer. 106:524–531. 2006. View Article : Google Scholar : PubMed/NCBI

13 

Shaha A: Treatment of thyroid cancer based on risk groups. J Surg Oncol. 94:683–691. 2006. View Article : Google Scholar : PubMed/NCBI

14 

Kupferman ME, Patterson M, Mandel SJ, LiVolsi V and Weber RS: Patterns of lateral neck metastasis in papillary thyroid carcinoma. Arch Otolaryngol Head Neck Surg. 130:857–860. 2004. View Article : Google Scholar : PubMed/NCBI

15 

Hassanain M and Wexler M: Conservative management of well-differentiated thyroid cancer. Can J Surg. 53:109–118. 2010.PubMed/NCBI

16 

Shaha AR, Shah JP and Loree TR: Patterns of nodal and distant metastasis based on histologic varieties in differentiated carcinoma of the thyroid. Am J Surg. 172:692–694. 1996. View Article : Google Scholar : PubMed/NCBI

17 

Hay ID, Bergstralh EJ, Grant CS, McIver B, Thompson GB, van Heerden JA and Goellner JR: Impact of primary surgery on outcome in 300 patients with pathologic tumor-node-metastasis stage III papillary thyroid carcinoma treated at one institution from 1940 through 1989. Surgery. 126:1173–1181; discussion 1181–1182. 1999. View Article : Google Scholar : PubMed/NCBI

18 

Pai SI and Tufano RP: Reoperation for recurrent/persistent well-differentiated thyroid cancer. Otolaryngol Clin North Am. 43353–363. (ix)2010. View Article : Google Scholar : PubMed/NCBI

19 

Betka J, Mrzena L, Astl J, Nemec J, Vlcek P, Taudy M and Skrivan J: Surgical treatment strategy for thyroid gland carcinoma nodal metastases. Eur Arch Otorhinolaryngol. 254 (Suppl 1):S169–S174. 1997. View Article : Google Scholar : PubMed/NCBI

20 

Scheumann GF, Seeliger H, Musholt TJ, Gimm O, Wegener G, Dralle H, Hundeshagen H and Pichlmayr R: Completion thyroidectomy in 131 patients with differentiated thyroid carcinoma. Eur J Surg. 162:677–684. 1996.PubMed/NCBI

21 

Travagli JP, Cailleux AF, Ricard M, Baudin E, Caillou B, Parmentier C and Schlumberger M: Combination of radioiodine (131I) and probe-guided surgery for persistent or recurrent thyroid carcinoma. J Clin Endocrinol Metab. 83:2675–2680. 1998. View Article : Google Scholar : PubMed/NCBI

22 

Rubello D, Salvatori M, Ardito G, Mariani G, Al-Nahhas A, Gross MD, Muzzio PC and Pelizzo MR: Iodine-131 radio-guided surgery in differentiated thyroid cancer: Outcome on 31 patients and review of the literature. Biomed Pharmacother. 61:477–481. 2007. View Article : Google Scholar : PubMed/NCBI

23 

Salvatori M, Ardito G, Pelizzo MR, Mariani G, Gross M, Al-Nahhas A and Rubello D: Treatment of local and regional recurrences of differentiated thyroid cancer by radio-guided surgery with iodine-131. Nucl Med Rev Cent East Eur. 9:119–124. 2006.PubMed/NCBI

24 

Lucchini R, Puxeddu E, Calzolari F, Burzelli F, Monacelli M, D'Ajello F, Macaluso R, Giammartino C, Ragusa M, De Feo P, et al: Recurrences of thyroid well differentiated cancer: Ultrasonography-guided surgical treatment. Minerva Chir. 63:257–260. 2008.PubMed/NCBI

25 

Duprez R, Lebas P, Marc OS, Mongeois E, Emy P and Michenet P: Preoperative US-guided hook-needle insertion in recurrent lymph nodes of papillary thyroid cancer: A help for the surgeon. Eur J Radiol. 73:40–42. 2010. View Article : Google Scholar : PubMed/NCBI

26 

Sippel RS, Elaraj DM, Poder L, Duh QY, Kebebew E and Clark OH: Localization of recurrent thyroid cancer using intraoperative ultrasound-guided dye injection. World J Surg. 33:434–439. 2009. View Article : Google Scholar : PubMed/NCBI

27 

Gulec SA, Eckert M and Woltering EA: Gamma probe-guided lymph node dissection (‘gamma picking’) in differentiated thyroid carcinoma. Clin Nucl Med. 27:859–861. 2002. View Article : Google Scholar : PubMed/NCBI

28 

Grant CS, Thompson GB, Farley DR, Richards ML, Mullan BP and Hay ID: The value of positron emission tomography in the surgical management of recurrent papillary thyroid carcinoma. World J Surg. 32:708–715. 2008. View Article : Google Scholar : PubMed/NCBI

29 

Borsò E, Grosso M, Boni G, Manca G, Bianchi P, Puccini M, Arganini M, Cabria M, Piccardo A, Arlandini A, et al: Radioguided occult lesion localization of cervical recurrences from differentiated thyroid cancer: Technical feasibility and clinical results. Q J Nucl Med Mol Imaging. 57:401–411. 2013.PubMed/NCBI

30 

Molina MA, Goodwin WJ, Moffat FL, Serafini AN, Sfakianakis GN and Avisar E: Intra-operative use of PET probe for localization of FDG avid lesions. Cancer Imaging. 9:59–62. 2009.PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Soprani F, De Vito A, Bondi F, Magliulo G, Rene SS, Cappi C, Riganti F, Vicini C and Puccetti M: Preoperative charcoal suspension tattoo for the detection of differentiated thyroid cancer recurrence. Mol Clin Oncol 10: 524-530, 2019.
APA
Soprani, F., De Vito, A., Bondi, F., Magliulo, G., Rene, S.S., Cappi, C. ... Puccetti, M. (2019). Preoperative charcoal suspension tattoo for the detection of differentiated thyroid cancer recurrence. Molecular and Clinical Oncology, 10, 524-530. https://doi.org/10.3892/mco.2019.1826
MLA
Soprani, F., De Vito, A., Bondi, F., Magliulo, G., Rene, S. S., Cappi, C., Riganti, F., Vicini, C., Puccetti, M."Preoperative charcoal suspension tattoo for the detection of differentiated thyroid cancer recurrence". Molecular and Clinical Oncology 10.5 (2019): 524-530.
Chicago
Soprani, F., De Vito, A., Bondi, F., Magliulo, G., Rene, S. S., Cappi, C., Riganti, F., Vicini, C., Puccetti, M."Preoperative charcoal suspension tattoo for the detection of differentiated thyroid cancer recurrence". Molecular and Clinical Oncology 10, no. 5 (2019): 524-530. https://doi.org/10.3892/mco.2019.1826
Copy and paste a formatted citation
x
Spandidos Publications style
Soprani F, De Vito A, Bondi F, Magliulo G, Rene SS, Cappi C, Riganti F, Vicini C and Puccetti M: Preoperative charcoal suspension tattoo for the detection of differentiated thyroid cancer recurrence. Mol Clin Oncol 10: 524-530, 2019.
APA
Soprani, F., De Vito, A., Bondi, F., Magliulo, G., Rene, S.S., Cappi, C. ... Puccetti, M. (2019). Preoperative charcoal suspension tattoo for the detection of differentiated thyroid cancer recurrence. Molecular and Clinical Oncology, 10, 524-530. https://doi.org/10.3892/mco.2019.1826
MLA
Soprani, F., De Vito, A., Bondi, F., Magliulo, G., Rene, S. S., Cappi, C., Riganti, F., Vicini, C., Puccetti, M."Preoperative charcoal suspension tattoo for the detection of differentiated thyroid cancer recurrence". Molecular and Clinical Oncology 10.5 (2019): 524-530.
Chicago
Soprani, F., De Vito, A., Bondi, F., Magliulo, G., Rene, S. S., Cappi, C., Riganti, F., Vicini, C., Puccetti, M."Preoperative charcoal suspension tattoo for the detection of differentiated thyroid cancer recurrence". Molecular and Clinical Oncology 10, no. 5 (2019): 524-530. https://doi.org/10.3892/mco.2019.1826
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