Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular and Clinical Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9450 Online ISSN: 2049-9469
Journal Cover
May-2019 Volume 10 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
May-2019 Volume 10 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

Chronic kidney disease and positive surgical margins as prognosticators for upper urinary tract urothelial carcinoma patients undergoing radical nephroureterectomy

  • Authors:
    • Kenji Kuroda
    • Junichi Asakuma
    • Akio Horiguchi
    • Makoto Kawaguchi
    • Masayuki Shinchi
    • Ayako Masunaga
    • Shinsuke Tasaki
    • Akinori Sato
    • Keiichi Ito
  • View Affiliations / Copyright

    Affiliations: Department of Urology, National Defense Medical College, Tokorozawa, Saitama 359‑8513, Japan
  • Pages: 547-554
    |
    Published online on: March 20, 2019
       https://doi.org/10.3892/mco.2019.1829
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Chronic kidney disease (CKD) is a common condition among elderly patients and has been reported to be a biomarker for the presence of malignant disease. In addition, unfavorable outcomes for patients with upper tract urothelial carcinoma (UTUC) undergoing radical nephroureterectomy can be due to independent clinical factors. Therefore, the present study analyzed the clinicopathological data of patients with UTUC, who underwent radical nephroureterectomy at our institution, to clarify whether preoperative CKD and other factors are independent predictors of the shorter disease‑specific and/or recurrence‑free survival time of these patients. A retrospective review of 187 patients who underwent radical nephroureterectomy was conducted, and patients were followed for at least 3 months postoperatively. The clinicopathological factors that are thought to have potentially significant roles in the progression and metastasis of malignant tumors and for disease‑specific and recurrence‑free survival were evaluated. Positive surgical margins and an estimation of the glomerular filtration rate (eGFR) of <60 were independent factors for the shorter disease‑specific survival time in multivariate analysis with Cox's proportional hazards model [hazard ratio (HR), 2.401: 95% confidence interval (CI), 1.044‑5.255; and HR, 2.371: 95% CI, 1.024‑5.898, respectively]. Another multivariate analysis also revealed that positive surgical margins (HR, 4.477; 95% CI, 2.042‑9.469), and preoperative eGFR <60 (HR, 2.362; 95% CI, 1.067‑5.592) were independent factors for the worse recurrence‑free survival rate in all patients. Patients with UTUC who had eGFR <60 as well as positive surgical margins had significantly shorter time to disease‑specific mortality and extraurothelial recurrence. The present study demonstrated that patients with UTUC undergoing radical nephroureterectomy who have CKD as well as positive surgical margins should be carefully followed up postoperatively.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Babjuk M, Böhle A, Burger M, Capoun O, Cohen D, Compérat EM, Hernández V, Kaasinen E, Palou J, Rouprêt M, et al: EAU Guidelines on non-muscle-invasive urothelial carcinoma of the bladder: Update 2016. Eur Urol. 71:447–461. 2017. View Article : Google Scholar : PubMed/NCBI

2 

Siegel R, Miller K and Jemal A: Cancer statistics, 2015. CA Cancer J Clin. 65:5–29. 2015. View Article : Google Scholar : PubMed/NCBI

3 

Munoz JJ and Ellison LM: Upper tract urothelial neoplasms: Incidence and survival during the last 2 decades. J Urol. 164:1523–1525. 2000. View Article : Google Scholar : PubMed/NCBI

4 

Cosentino M, Palou J, Gaya JM, Breda A, Rodriguez-Faba O and Villavicencio-Mavrich H: Upper urinary tract urothelial cell carcinoma: Location as a predictive factor for concomitant bladder carcinoma. World J Urol. 31:141–145. 2013. View Article : Google Scholar : PubMed/NCBI

5 

Seisen T, Granger B, Colin P, Léon P, Utard G, Renard-Penna R, Compérat E, Mozer P, Cussenot O, Shariat SF and Rouprêt M: A systematic review and meta-analysis of clinicopathologic factors linked to intravesical recurrence after radical nephroureterectomy to treat upper tract urothelial carcinoma. Eur Urol. 67:1122–1133. 2015. View Article : Google Scholar : PubMed/NCBI

6 

Novara G, De Marco V, Dalpiaz O, Galfano A, Bouygues V, Gardiman M, Martignoni G, Patard JJ, Artibani W and Ficarra V: Independent predictors of contralateral metachronous upper urinary tract transitional cell carcinoma after nephroureterectomy: Multi-institutional dataset from three European centers. Int J Urol. 16:187–191. 2009. View Article : Google Scholar : PubMed/NCBI

7 

Li WM, Shen JT, Li CC, Ke HL, Wei YC, Wu WJ, Chou YH and Huang CH: Oncologic outcomes following three different approaches to the distal ureter and bladder cuff in nephroureterectomy for primary upper urinary tract urothelial carcinoma. Eur Urol. 57:963–969. 2010. View Article : Google Scholar : PubMed/NCBI

8 

Matas AJ, Simmons RL, Kjellstrand CM, Buselmeier TJ and Najarian JS: Increased incidence of malignancy during chronic renal failure. Lancet. 1:883–886. 1975. View Article : Google Scholar : PubMed/NCBI

9 

Cengiz K: Increased incidence of neoplasia in chronic renal failure (20-year experience). Int Urol Nephrol. 33:121–126. 2002. View Article : Google Scholar : PubMed/NCBI

10 

Stewart JH: Cancers of the kidney and urinary tract in patients on dialysis for end-stage renal disease: Analysis of data from the United states, Europe, and Australia and New Zealand. J Am Soc Nephrol. 14:197–207. 2003. View Article : Google Scholar : PubMed/NCBI

11 

Ito K, Kuroda K, Asakuma J, Hamada S, Tasaki S, Tasaki S, Sato A, Horiguchi A, Seguchi K and Asano T: Preoperative risk factors for extraurothelial recurrence in patients with ureteral cancer treated with radical nephroureterectomy. J Urol. 191:1685–1692. 2014. View Article : Google Scholar : PubMed/NCBI

12 

Kuroda K, Asakuma J, Horiguchi A, Tasaki S, Yoshii H, Sato A, Ito K, Seguchi K, Sumitomo M and Asano T: Prognostic factors for upper urinary tract urothelial carcinoma after nephroureterectomy. Urol Int. 88:225–231. 2012. View Article : Google Scholar : PubMed/NCBI

13 

Bolenz C, Shariat SF, Fernández MI, Margulis V, Lotan Y, Karakiewicz P, Remzi M, Kikuchi E, Zigeuner R, Weizer A, et al: Risk stratification of patients with nodal involvement in upper tract urothelial carcinoma: Value of lymph-node density. BJU Int. 103:302–306. 2009. View Article : Google Scholar : PubMed/NCBI

14 

Sobin L, Gospodarowicz M and Wittekind C: TNM Classification of Malignant Tumours. (7th). 2009.

15 

John E, Guido S, Jonathan E and Isabell S: Pathology and Genetics: Tumours of the Urinary System and Male Genital System (IARC WHO Classification of Tumours). 2004.

16 

Qu JL, Qu XJ, Li Z, Zhang JD, Liu J, Teng YE, Jin B, Zhao MF, Yu P, Shi J, et al: Prognostic model based on systemic inflammatory response and clinicopathological factors to predict outcome of patients with Node-Negative gastric cancer. PLoS One. 10:e01285402015. View Article : Google Scholar : PubMed/NCBI

17 

Yuksel OH, Akan S, Uukmez A, Yildirim C, Sahin A and Verit A: Preoperative glasgow prognostic score as a predictor of primary bladder cancer recurrence. Mol Clin Oncol. 5:201–206. 2016. View Article : Google Scholar : PubMed/NCBI

18 

Imai E, Horio M, Nitta K, Yamagata K, Iseki K, Tsukamoto Y, Ito S, Makino H, Hishida A and Matsuo S: Modification of the modification of diet in renal disease (MDRD) Study equation for Japan. Am J Kidney Dis. 50:927–937. 2007. View Article : Google Scholar : PubMed/NCBI

19 

Kang M, Jeong CW, Kwak C, Kim HH and Ku JH: Preoperative neutrophil-lymphocyte ratio can significantly predict mortality outcomes in patients with non-muscle invasive bladder cancer undergoing transurethral resection of bladder tumor. Oncotarget. 8:12891–12901. 2016.

20 

Uemura K, Kawahara T, Yamashita D, Jikuya R, Abe K, Tatenuma T, Yokomizo Y, Izumi K, Teranishi JI, Makiyama K, et al: Neutrophil-to-lymphocyte ratio predicts prognosis in castration-resistant prostate cancer patients who received cabazitaxel chemotherapy. Biomed Res Int. 2017:75386472017. View Article : Google Scholar : PubMed/NCBI

21 

Gunes A, Yigit M, Tok L and Tok O: Neutrophil to lymphocyte ratio in patients with nonarteritic anterior Ischemic optic neuropathy. Korean J Ophthalmol. 31:159–164. 2017. View Article : Google Scholar : PubMed/NCBI

22 

Kasuga J, Kawahara T, Takamoto D, Fukui S, Tokita T, Tadenuma T, Narahara M, Fusayasu S, Terao H, Izumi K, et al: Increased neutrophil-to-lymphocyte ratio is associated with disease-specific mortality in patients with penile cancer. BMC Cancer. 16:3962016. View Article : Google Scholar : PubMed/NCBI

23 

Li CE, Chien CS, Chuang YC, HP T and CH K: Chronic kidney disease as an important risk factor for tumor recurrences, progression and overall survival in primary non-muscle-invasive bladder cancer. Int Urol Nephrol. 48:993–999. 2016. View Article : Google Scholar : PubMed/NCBI

24 

Kim YW, Kim WT, Yun SJ, Lee SC, Kim WJ, Ha YS, Park YH, Kang SH, Hong SH, Kwon TG, et al: Preoperative chronic kidney disease status is an independent prognostic factor in patients with renal cell carcinoma. Ann Surg Oncol. 22:4098–4103. 2015. View Article : Google Scholar : PubMed/NCBI

25 

Tollefson MK, Boorjian SA, Gettman MT, Rangel LJ, Bergstralh EJ and Karnes RJ: Preoperative estimated glomerular filtration rate predicts overall mortality in patients undergoing radical prostatectomy. Urol Oncol. 31:1483–1488. 2013. View Article : Google Scholar : PubMed/NCBI

26 

Morizane S, Yumioka T, Yamaguchi N, Masago T, Honda M, Sejima T and Takenaka A: Risk stratification model, including preoperative serum C-reactive protein and estimated glomerular filtration rate levels, in patients with upper urinary tract urothelial carcinoma undergoing radical nephroureterectomy. Int Urol Nephrol. 47:1335–1341. 2015. View Article : Google Scholar : PubMed/NCBI

27 

Li CC, Chang TH, Wu WJ, Ke HL, Huang SP, Tsai PC, Chang SJ, Shen JT, Chou YH and Huang CH: Significant predictive factors for prognosis of primary upper urinary tract cancer after radical nephroureterectomy in Taiwanese patients. Eur Urol. 54:1127–1134. 2008. View Article : Google Scholar : PubMed/NCBI

28 

Wu CF, Chang PL, Chen CS, Chuang CK, Weng HH and Pang ST: The outcome of patients on dialysis with upper urinary tract transitional cell carcinoma. J Urol. 176:477–481. 2006. View Article : Google Scholar : PubMed/NCBI

29 

Yu HS, Hwang JE, Chung HS, Cho YH, Kim MS, Hwang EC, Oh KJ, Kim SO, Jung SI, Kang TW, et al: Is preoperative chronic kidney disease status associated with oncologic outcomes in upper urinary tract urothelial carcinoma? A multicenter propensity score-matched analysis. Oncotarget. 8:66540–66549. 2017.PubMed/NCBI

30 

Li WM, Li CC, Ke HL, Wu WJ, Huang CN and Huang CH: The prognostic predictors of primary ureteral transitional cell carcinoma after radical Nephroureterectomy. J Urol. 182:451–458. 2009. View Article : Google Scholar : PubMed/NCBI

31 

Ou JH, Pan CC, Lin JS, Tzai TS, Yang WH, Chang CC, Cheng HL, Lin YM and Tong YC: Transitional cell carcinoma in dialysis patients. Eur Urol. 37:90–94. 2000. View Article : Google Scholar : PubMed/NCBI

32 

Chang CH, Yang CM and Yang AH: Renal diagnosis of chronic hemodialysis patients with urinary tract transitional cell carcinoma in Taiwan. Cancer. 109:1487–1492. 2007. View Article : Google Scholar : PubMed/NCBI

33 

Chen KS, Lai MK, Huang CC, Chu SH and Leu ML: Urologic cancers in uremic patients. Am J Kidney Dis. 25:694–700. 1995. View Article : Google Scholar : PubMed/NCBI

34 

Kato S, Chmielewski M, Honda H, Pecoits-Filho R, Matsuo S, Yuzawa Y, Tranaeus A, Stenvinkel P and Lindholm B: Aspects of immune dysfunction in end-stage renal disease. Clin J Am Soc Nephrol. 3:1526–1533. 2008. View Article : Google Scholar : PubMed/NCBI

35 

Vamvakas S, Bahner U and Heidland A: Cancer in end-stage renal disease: Potential factors involved. Am J Nephrol. 18:89–95. 1998. View Article : Google Scholar : PubMed/NCBI

36 

Stopper H, Meysen T, Bockenforde A, Bahner U, Heidland A and Vamvakas S: Increased genomic damage in lymphocytes of patients before and after long-term maintenance hemodialysis therapy. Am J Kidney Dis. 34:433–437. 1999. View Article : Google Scholar : PubMed/NCBI

37 

Song X, Zhang GM, Ma XC, Luo L, Li B, Chai DY and Sun L: Comparison of preoperative neutrophil-lymphocyte, lymphocyte-monocyte, and platelet-lymphocyte ratios in patients with upper urinary tract urothelial carcinoma undergoing radical nephroureterectomy. Onco Targets Ther. 9:1399–1407. 2016. View Article : Google Scholar : PubMed/NCBI

38 

Keller CR, Odden MC, Fried LF, Newman AB, Angleman S, Green CA, Cummings SR, Harris TB and Shlipak MG: Kidney function and markers of inflammation in elderly persons without chronic kidney disease: The health, aging, and body composition study. Kidney Int. 71:239–244. 2007. View Article : Google Scholar : PubMed/NCBI

39 

Colin P, Ghoneim TP, Nison L, Seisen T, Lechevallier E, Cathelineau X, Ouzzane A, Zerbib M, Long JA, Ruffion A, et al: Risk stratification of metastatic recurrence in invasive upper urinary tract carcinoma after radical nephroureterectomy without lymphadenectomy. World J Urol. 32:507–512. 2014. View Article : Google Scholar : PubMed/NCBI

40 

Allard CB, Alamri A, Dason S, Farrokhyar F, Matsumoto ED and Kapoor A: The method of bladder cuff excision during laparoscopic radical nephroureterectomy does not affect oncologic outcomes in upper tract urothelial carcinoma. World J Urol. 31:175–181. 2013. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Kuroda K, Asakuma J, Horiguchi A, Kawaguchi M, Shinchi M, Masunaga A, Tasaki S, Sato A and Ito K: Chronic kidney disease and positive surgical margins as prognosticators for upper urinary tract urothelial carcinoma patients undergoing radical nephroureterectomy. Mol Clin Oncol 10: 547-554, 2019.
APA
Kuroda, K., Asakuma, J., Horiguchi, A., Kawaguchi, M., Shinchi, M., Masunaga, A. ... Ito, K. (2019). Chronic kidney disease and positive surgical margins as prognosticators for upper urinary tract urothelial carcinoma patients undergoing radical nephroureterectomy. Molecular and Clinical Oncology, 10, 547-554. https://doi.org/10.3892/mco.2019.1829
MLA
Kuroda, K., Asakuma, J., Horiguchi, A., Kawaguchi, M., Shinchi, M., Masunaga, A., Tasaki, S., Sato, A., Ito, K."Chronic kidney disease and positive surgical margins as prognosticators for upper urinary tract urothelial carcinoma patients undergoing radical nephroureterectomy". Molecular and Clinical Oncology 10.5 (2019): 547-554.
Chicago
Kuroda, K., Asakuma, J., Horiguchi, A., Kawaguchi, M., Shinchi, M., Masunaga, A., Tasaki, S., Sato, A., Ito, K."Chronic kidney disease and positive surgical margins as prognosticators for upper urinary tract urothelial carcinoma patients undergoing radical nephroureterectomy". Molecular and Clinical Oncology 10, no. 5 (2019): 547-554. https://doi.org/10.3892/mco.2019.1829
Copy and paste a formatted citation
x
Spandidos Publications style
Kuroda K, Asakuma J, Horiguchi A, Kawaguchi M, Shinchi M, Masunaga A, Tasaki S, Sato A and Ito K: Chronic kidney disease and positive surgical margins as prognosticators for upper urinary tract urothelial carcinoma patients undergoing radical nephroureterectomy. Mol Clin Oncol 10: 547-554, 2019.
APA
Kuroda, K., Asakuma, J., Horiguchi, A., Kawaguchi, M., Shinchi, M., Masunaga, A. ... Ito, K. (2019). Chronic kidney disease and positive surgical margins as prognosticators for upper urinary tract urothelial carcinoma patients undergoing radical nephroureterectomy. Molecular and Clinical Oncology, 10, 547-554. https://doi.org/10.3892/mco.2019.1829
MLA
Kuroda, K., Asakuma, J., Horiguchi, A., Kawaguchi, M., Shinchi, M., Masunaga, A., Tasaki, S., Sato, A., Ito, K."Chronic kidney disease and positive surgical margins as prognosticators for upper urinary tract urothelial carcinoma patients undergoing radical nephroureterectomy". Molecular and Clinical Oncology 10.5 (2019): 547-554.
Chicago
Kuroda, K., Asakuma, J., Horiguchi, A., Kawaguchi, M., Shinchi, M., Masunaga, A., Tasaki, S., Sato, A., Ito, K."Chronic kidney disease and positive surgical margins as prognosticators for upper urinary tract urothelial carcinoma patients undergoing radical nephroureterectomy". Molecular and Clinical Oncology 10, no. 5 (2019): 547-554. https://doi.org/10.3892/mco.2019.1829
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team