Magnetic resonance relaxometry improves the accuracy of conventional MRI in the diagnosis of endometriosis‑associated ovarian cancer: A case report

Matsubara,Sho; Kawahara,Naoki; Horie,Akihito; Murakami,Ryusuke; Horikawa,Naoki; Sumida,Daichi; Wada,Takuya; Maehana,Tomoka; Yamawaki,Aika; Ichikawa,Mayuko; Yoshimoto,Chiharu; Mandai,Masaki; Kobayashi,Hiroshi

doi:10.3892/mco.2019.1889

September-2019 Volume 11 Issue 3

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September-2019 Volume 11 Issue 3

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Case Report

Magnetic resonance relaxometry improves the accuracy of conventional MRI in the diagnosis of endometriosis‑associated ovarian cancer: A case report

Authors:
- Sho Matsubara
- Naoki Kawahara
- Akihito Horie
- Ryusuke Murakami
- Naoki Horikawa
- Daichi Sumida
- Takuya Wada
- Tomoka Maehana
- Aika Yamawaki
- Mayuko Ichikawa
- Chiharu Yoshimoto
- Masaki Mandai
- Hiroshi Kobayashi
View Affiliations / Copyright

Affiliations: Department of Obstetrics and Gynecology, Nara Medical University, Kashihara, Nara 634‑8522, Japan, Department of Obstetrics and Gynecology, Kyoto University, Kyoto 606‑8507, Japan
Pages: 296-300
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Published online on: July 1, 2019

https://doi.org/10.3892/mco.2019.1889
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Abstract

Endometriosis is a precancerous condition for endometriosis‑associated ovarian cancer (EAOC). In the present study, conventional magnetic resonance imaging (MRI) and MR relaxometry were used to examine a case of clear cell carcinoma that arose in a pre‑existing right‑sided benign ovarian endometrioma (OE). The 42‑year‑old nulliparous woman suspected of EOAC, as assessed by conventional MRI, requested fertility‑sparing surgery such as laparoscopic endometrioma cystectomy. Furthermore, the MR transverse relaxation rate (R2) was determined using a single‑voxel, multi‑echo MR sequence using a 3 Tesla‑MR system. An R2 value <12.1 s‑1 was indicative of malignancy, as described in previous studies. In the present study, MR relaxometry identified an R2 value of 7.98 s‑1 in the right cyst, which suggested the malignant transformation of benign OE. Based on these findings, fertility‑sparing surgery was contraindicated. In conclusion, MR relaxometry may represent a new clinical approach as an adjunctive modality for the diagnosis of EAOC. When patients exhibiting a pelvic mass suspected of EAOC desire fertility‑sparing treatment options, MR relaxometry can facilitate the selection of conservative management.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Magnetic resonance relaxometry improves the accuracy of conventional MRI in the diagnosis of endometriosis‑associated ovarian cancer: A case report

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