Intracholecystic papillary neoplasm of the gallbladder protruding into the common bile duct: A case report

Yokode,Masataka; Hanada,Keiji; Shimizu,Akinori; Minami,Tomoyuki; Hirohata,Ryosuke; Abe,Tomoyuki; Amano,Hironobu; Yonehara,Shuji; Zen,Yoh

doi:10.3892/mco.2019.1919

November-2019 Volume 11 Issue 5

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November-2019 Volume 11 Issue 5

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Case Report Open Access

Intracholecystic papillary neoplasm of the gallbladder protruding into the common bile duct: A case report

Authors:
- Masataka Yokode
- Keiji Hanada
- Akinori Shimizu
- Tomoyuki Minami
- Ryosuke Hirohata
- Tomoyuki Abe
- Hironobu Amano
- Shuji Yonehara
- Yoh Zen
View Affiliations / Copyright

Affiliations: Department of Gastroenterology, Onomichi General Hospital, Onomichi, Hiroshima 722‑8508, Japan, Department of Surgery, Onomichi General Hospital, Onomichi, Hiroshima 722‑8508, Japan, Department of Pathology, Onomichi General Hospital, Onomichi, Hiroshima 722‑8508, Japan, Institute of Liver Studies, King's College Hospital, London SE5 9RS, UK

Copyright: © Yokode et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 488-492
|
Published online on: September 9, 2019

https://doi.org/10.3892/mco.2019.1919
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Abstract

The current study indicates the case of intracholecystic papillary neoplasm (ICPN) protruding into the common bile duct (CBD) without superficial spread. A 58‑year‑old woman presented to hospital with a fever that lasted for three days. Laboratory tests revealed elevated hepatobiliary enzyme levels. CT, MRI and endoscopic ultrasonography revealed a polypoid, papillary tumor inside the gallbladder cavity, which also extended to the CBD. On peroral cholangioscopy, a papillary tumor with mucin production was found at the middle bile duct. Biliary biopsy and bile cytology indicated adenocarcinoma. Based on a diagnosis of ICPN extending to the CBD, the patient underwent subtotal stomach‑preserving pancreaticoduodenectomy and gallbladder bed resection. However, pathological examination revealed that the ICPN was confined to the gallbladder and cystic duct, whereas the CBD was tumor‑free. The present case indicates that when ICPN increases in size, it may protrude into the CBD due to an increased intracholecystic pressure, which increases the risk of overestimation of tumor extension and may result in unnecessary additional bile duct resection.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Intracholecystic papillary neoplasm of the gallbladder protruding into the common bile duct: A case report

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