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Article

Quantitative assessment of radiodermatitis through a non‑invasive objective procedure in patients with breast cancer

  • Authors:
    • Maiko Kitajima
    • Kasumi Mikami
    • Yuka Noto
    • Chieko Itaki
    • Yasuyo Fukushi
    • Yoshiko Hirota
    • Yasushi Mariya
    • Megumi Tsushima
    • Keiichi Kattou
    • Tomohiro Osanai
  • View Affiliations / Copyright

    Affiliations: Department of Nursing Science, Hirosaki University Graduate School of Health Science, Hirosaki, Aomori 036‑8564, Japan, Department of Radiology, Mutsu General Hospital, Mutsu, Aomori 035‑8601, Japan, Hirosaki Central Hospital, Hirosaki, Aomori 036‑8188, Japan
  • Pages: 89-93
    |
    Published online on: November 11, 2019
       https://doi.org/10.3892/mco.2019.1948
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Abstract

Assessment of skin condition is necessary for providing advice regarding skin self‑care to patients with breast cancer who have undergone radiation therapy. Acute and chronic phases of radiodermatitis were analyzed in patients using objective assessment tools in the present study. A total of 18 women who received radiation therapy for breast cancer were enrolled in the present study and their skin surface temperature (SST), hydration level of the skin surface (HL), melanin intensity (MI) and erythema intensity (EI) were measured prior to radiation therapy and six months thereafter. Furthermore, skin condition was assessed using the Common Terminology Criteria for Adverse Events (CTCAE). EI and MI levels at the irradiated site peaked upon the completion of radiation therapy and declined to baseline at 6 months. In contrast, SST levels were elevated at the irradiated site during radiation therapy (P<0.05) and plateaued after its completion. The same parameters in non‑irradiated control sites remained unchanged during the study period. HL reached the minimum in irradiated and non‑irradiated sites upon completion of radiation therapy. Although HL returned to baseline in the non‑irradiated site 6 months after radiation therapy, it remained low in the irradiated site. No relationship between the CTCAE and EI level was observed. In conclusion, the present study demonstrated that objective assessment tools, including SST and EI levels, were useful for assessing skin condition during radiodermatitis. The combination of the CTCAE and objective assessment tools will enable a more accurate assessment of radiodermatitis.
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Copy and paste a formatted citation
Spandidos Publications style
Kitajima M, Mikami K, Noto Y, Itaki C, Fukushi Y, Hirota Y, Mariya Y, Tsushima M, Kattou K, Osanai T, Osanai T, et al: Quantitative assessment of radiodermatitis through a non‑invasive objective procedure in patients with breast cancer. Mol Clin Oncol 12: 89-93, 2020.
APA
Kitajima, M., Mikami, K., Noto, Y., Itaki, C., Fukushi, Y., Hirota, Y. ... Osanai, T. (2020). Quantitative assessment of radiodermatitis through a non‑invasive objective procedure in patients with breast cancer. Molecular and Clinical Oncology, 12, 89-93. https://doi.org/10.3892/mco.2019.1948
MLA
Kitajima, M., Mikami, K., Noto, Y., Itaki, C., Fukushi, Y., Hirota, Y., Mariya, Y., Tsushima, M., Kattou, K., Osanai, T."Quantitative assessment of radiodermatitis through a non‑invasive objective procedure in patients with breast cancer". Molecular and Clinical Oncology 12.1 (2020): 89-93.
Chicago
Kitajima, M., Mikami, K., Noto, Y., Itaki, C., Fukushi, Y., Hirota, Y., Mariya, Y., Tsushima, M., Kattou, K., Osanai, T."Quantitative assessment of radiodermatitis through a non‑invasive objective procedure in patients with breast cancer". Molecular and Clinical Oncology 12, no. 1 (2020): 89-93. https://doi.org/10.3892/mco.2019.1948
Copy and paste a formatted citation
x
Spandidos Publications style
Kitajima M, Mikami K, Noto Y, Itaki C, Fukushi Y, Hirota Y, Mariya Y, Tsushima M, Kattou K, Osanai T, Osanai T, et al: Quantitative assessment of radiodermatitis through a non‑invasive objective procedure in patients with breast cancer. Mol Clin Oncol 12: 89-93, 2020.
APA
Kitajima, M., Mikami, K., Noto, Y., Itaki, C., Fukushi, Y., Hirota, Y. ... Osanai, T. (2020). Quantitative assessment of radiodermatitis through a non‑invasive objective procedure in patients with breast cancer. Molecular and Clinical Oncology, 12, 89-93. https://doi.org/10.3892/mco.2019.1948
MLA
Kitajima, M., Mikami, K., Noto, Y., Itaki, C., Fukushi, Y., Hirota, Y., Mariya, Y., Tsushima, M., Kattou, K., Osanai, T."Quantitative assessment of radiodermatitis through a non‑invasive objective procedure in patients with breast cancer". Molecular and Clinical Oncology 12.1 (2020): 89-93.
Chicago
Kitajima, M., Mikami, K., Noto, Y., Itaki, C., Fukushi, Y., Hirota, Y., Mariya, Y., Tsushima, M., Kattou, K., Osanai, T."Quantitative assessment of radiodermatitis through a non‑invasive objective procedure in patients with breast cancer". Molecular and Clinical Oncology 12, no. 1 (2020): 89-93. https://doi.org/10.3892/mco.2019.1948
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