search button
Open Access

Rare amyloidoma of the tongue base: A case report and review of the literature

  • Authors:
    • Gabriela Musat
    • Anca Evsei
    • Daniela Calina
    • Anca Oana Docea
    • Sotirios G. Doukas
    • Dimitra P. Vageli
    • Charitini Nepka
    • Demetrios A. Spandidos
    • Mihaela Mitroi

  • View Affiliations

  • Published online on: January 9, 2020     https://doi.org/10.3892/mco.2020.1972
  • Pages: 258-262

  • Copyright: © Musat et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Localized amyloidosis is a rare condition characterized by the deposition of misfolding protein in a tissue, without other systemic manifestations. Only a small number of cases of localized amyloidosis of the tongue have been reported to date, in contrast to systemic amyloidosis, in which localization on the tongue is common. This study presents a rare case of localized amyloidosis of the tongue (amyloidoma) and provides a summary of the known literature of localized amyloidosis. This study describes the case of a 36‑year‑old female who presented with a swelling of the tongue base. The diagnosis of amyloidoma was made based on the findings of the physical examination, head and neck MRI findings and the histopathological examination with Congo red stain under polarized light. The histopathological diagnosis was as follows: Localized lambda light‑chain amyloidosis. A thorough physical examination was performed by the ENT and Hematology/Oncology departments, without revealing signs of systemic disease. A series of hematological and imaging tests were also performed to verify that there was no sign of systemic involvement. The patient declined surgical excision and the 2‑year follow‑up did not reveal any changes in tumor dimension. Although the etiology of localized amyloidosis is yet not clear, the prolonged reaction of tissue plasma cells to environmental antigens may be a causative factor for the initiation of the neoplastic process.
View Figures
View References

Related Articles

Journal Cover

March-2020
Volume 12 Issue 3

Print ISSN: 2049-9450
Online ISSN:2049-9469

Sign up for eToc alerts

Recommend to Library

  • Journal Metrics
  • Impact Factor: 1.2
  • Ranked
    (total number of cites)
  • CiteScore: 2.6
  • CiteScore Rank: Q3: #242/366 Oncology
  • Source Normalized Impact per Paper (SNIP): 0.693
  • SCImago Journal Rank (SJR): 0.393
International Symposium on Molecular Medicine Conference Banner
The Cancer Story
World Congress on Advances in Oncology and International Symposium on Molecular Medicine Conference Banner
World Academy Of Sciences Banner
Heyday Road Banner

0

Copy and paste a formatted citation
x
Spandidos Publications style
Musat G, Evsei A, Calina D, Docea AO, Doukas SG, Vageli DP, Nepka C, Spandidos DA and Mitroi M: Rare amyloidoma of the tongue base: A case report and review of the literature. Mol Clin Oncol 12: 258-262, 2020
APA
Musat, G., Evsei, A., Calina, D., Docea, A.O., Doukas, S.G., Vageli, D.P. ... Mitroi, M. (2020). Rare amyloidoma of the tongue base: A case report and review of the literature. Molecular and Clinical Oncology, 12, 258-262. https://doi.org/10.3892/mco.2020.1972
MLA
Musat, G., Evsei, A., Calina, D., Docea, A. O., Doukas, S. G., Vageli, D. P., Nepka, C., Spandidos, D. A., Mitroi, M."Rare amyloidoma of the tongue base: A case report and review of the literature". Molecular and Clinical Oncology 12.3 (2020): 258-262.
Chicago
Musat, G., Evsei, A., Calina, D., Docea, A. O., Doukas, S. G., Vageli, D. P., Nepka, C., Spandidos, D. A., Mitroi, M."Rare amyloidoma of the tongue base: A case report and review of the literature". Molecular and Clinical Oncology 12, no. 3 (2020): 258-262. https://doi.org/10.3892/mco.2020.1972