Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular and Clinical Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9450 Online ISSN: 2049-9469
Journal Cover
March-2020 Volume 12 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
March-2020 Volume 12 Issue 3

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Short term treatment results of local ablation with water‑cooled microwave antenna for liver cancer: Comparison with radiofrequency ablation

  • Authors:
    • Kanehiko Suwa
    • Toshihito Seki
    • Rinako Tsuda
    • Masao Yamashina
    • Miki Murata
    • Takashi Yamaguchi
    • Akiyoshi Nishio
    • Kazuichi Okazaki
  • View Affiliations / Copyright

    Affiliations: The Third Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kansai Medical University, Hirakata, Osaka 573‑1101, Japan, Kansai Medical University Medical Center, Liver Disease Center, Moriguchi, Osaka 570‑8507, Japan
    Copyright: © Suwa et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 230-236
    |
    Published online on: January 21, 2020
       https://doi.org/10.3892/mco.2020.1983
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The aim of the present study was to evaluate the efficacy and safety of the new‑generation percutaneous microwave ablation (MWA) compared with the radiofrequency ablation (RFA) system for the treatment of hepatocellular carcinoma (HCC). A retrospective study was conducted from January 2014 to February 2019. A total of 44 patients and 52 nodules (mean tumor size, 17.2±4.9 mm) were treated with MWA, and 55 patients and 70 nodules (mean tumor size, 17.7±6.4 mm) were treated with RFA. After 4 days of treatment, the direct effects of ablation were assessed using dynamic CT, and after discharge, a follow‑up dynamic CT scan was performed every 3‑4 months. Treatment efficacy, complications and local recurrence were recorded. For MWA and RFA, the average number of CT sessions were 1.05±0.23 and 1.28±0.54, respectively, and the mean ablation times were 5.0±2.0 and 8.1±4.8 min. Following MWA and RFA, the ablation ranges that were evaluated with the axial images were 31.9±5.5 and 33.3±9.0 mm, respectively, in the long‑axis diameter and 27.6±5.3 and 23.4±6.8 mm, respectively, in the short‑axis diameter. The flatness ratios of the ablation regions were 0.13±0.09 and 0.29±0.14 (axial image) and 0.11±0.07 and 0.28±0.14 (coronal image), respectively. The rates of complete tumor necrosis were comparable. The complication rates were 13.6% (MWA) and 14.5% (RFA), which were not significantly different. The cumulative local recurrence rates were not significantly different between the two methods (one‑year recurrence rate, MWA: 6.91%, RFA: 5.17%). MWA was therefore indicated to be an effective treatment for HCC in respect to session number, treatment time and spherical ablation.
View Figures

Figure 1

Figure 2

Figure 3

View References

1 

El-Serag HB: Epidemiology of viral hepatitis and hepatocellular carcinoma. Gastroenterology. 142:1264–1273. 2012.PubMed/NCBI View Article : Google Scholar

2 

Lencioni R: Loco-Regional treatment of hepatocellular carcinoma in the era of molecular targeted therapies. Oncology. 78:107–112. 2010.PubMed/NCBI View Article : Google Scholar

3 

Llovet JM: Updated treatment approach to hepatocellular carcinoma. J Gastroenterol. 40:225–235. 2005.PubMed/NCBI View Article : Google Scholar

4 

European Association for the Study of the Liver; European Organisation for Research and Treatment of Cancer: EASL-EORTC clinical practice guidelines: Management of hepatocellular carcinoma. J Hepatol 56: 908-943, 2012.

5 

Bruix J and Sherman M: Practice Guidelines Committee American Association for the Study of Liver Diseases: Management of hepatocellular carcinoma. Hepatology. 42:1208–1236. 2005.PubMed/NCBI View Article : Google Scholar

6 

Bruix J and Sherman M: American Association for the Study of Liver Diseases: Management of hepatocellular carcinoma: An update. Hepatology. 53:1020–1022. 2011.PubMed/NCBI View Article : Google Scholar

7 

McCarley JR and Soulen MC: Percutaneous ablation of hepatic tumors. Semin Intervent Radiol. 27:255–260. 2010.PubMed/NCBI View Article : Google Scholar

8 

Shiina S, Teratani T, Obi S, Hamamura K, Koike Y and Omata M: Nonsurgical treatment of hepatocellular carcinoma: From percutaneous ethanol injection therapy and percutaneous microwave coagulation therapy to radiofrequency ablation. Oncology. 62:64–68. 2002.PubMed/NCBI View Article : Google Scholar

9 

Yamasaki T, Kurokawa F, Shirahashi H, Kusano N, Hironaka K and Okita K: Percutaneous radiofrequency ablation therapy with combined angiography and computed tomography assistance for patients with hepatocellular carcinoma. Cancer. 91:1342–1348. 2001.PubMed/NCBI View Article : Google Scholar

10 

Lu DS, Raman SS, Limanond P, Aziz D, Economou J, Busuttil R and Sayre J: Influence of large peritumoral vessels on outcome of radiofrequency ablation of liver tumors. J Vasc Inter Radiol. 14:1267–1274. 2003.PubMed/NCBI View Article : Google Scholar

11 

Ierardi AM, Mangano A, Floridi C, Dionigi G, Biondi A, Duka E, Lucchina N, Lianos GD and Carrafiello G: A new system of microwave ablation at 2450 MHz: Preliminary experience. Updates Surg. 67:39–45. 2015.PubMed/NCBI View Article : Google Scholar

12 

Alonzo M, Bos A, Bennett S and Ferral H: The emprint ablation system with thermosphere technology: One of the newer next-generation microwave ablation technologies. Semin Intervent Radiol. 32:335–338. 2015.PubMed/NCBI View Article : Google Scholar

13 

Thandassery RB, Goenka U and Goenka MK: Role of local ablative therapy for hepatocellular carcinoma. J Clin Exp Hepatol. 4 (Suppl 3):S104–S111. 2014.PubMed/NCBI View Article : Google Scholar

14 

Shiina S, Sato K, Tateishi R, Shimizu M, Ohama H, Hatanaka T, Takawa M, Nagamatsu H and Imai Y: Percutaneous ablation for hepatocellular carcinoma: Comparison of various ablation techniques and surgery. Can J Gastroenterol Hepatol. 2018(4756147)2018.PubMed/NCBI View Article : Google Scholar

15 

Seki T, Wakabayashi M, Nakagawa T, Itho T, Shiro T, Kunieda K, Sato M, Uchiyama S and Inoue K: Ultrasonically guided percutaneous microwave coagulation therapy for small hepatocellular carcinoma. Cancer. 74:817–825. 1994.PubMed/NCBI View Article : Google Scholar

16 

Seki T, Tamai T, Nakagawa T, Imamura M, Nishimura A, Yamashiki N, Ikeda K and Inoue K: Combination therapy with transcatheter arterial chemoembolization and percutaneous microwave coagulation therapy for hepatocellular carcinoma. Cancer. 89:1245–1251. 2000.PubMed/NCBI

17 

Vogl TJ, Farshid P, Naguib NN, Zangos S, Bodelle B, Paul J, Mbalisike EC, Beeres M and Nour-Eldin NE: Ablation therapy of hepatocellular carcinoma: A comparative study between radiofrequency and microwave ablation. Abdom Imaging. 40:1829–1837. 2015.PubMed/NCBI View Article : Google Scholar

18 

Facciorusso A, Di Maso M and Muscatiello N: Microwave ablation versus radiofrequency ablation for the treatment of hepatocellular carcinoma: A systematic review and meta-analysis. Int J Hyperthermia. 32:339–344. 2016.PubMed/NCBI View Article : Google Scholar

19 

Zhou Y, Zhao Y, Li B, Xu D, Yin Z, Xie F and Yang J: Meta-analysis of radiofrequency ablation versus hepatic resection for small hepatocellular carcinoma. BMC Gastroenterol. 10(78)2010.PubMed/NCBI View Article : Google Scholar

20 

Feng K, Yan J, Li X, Xia F, Ma K, Wang S, Bie P and Dong J: A randomized controlled trial of radiofrequency ablaion and surgical resection in the treatment of small hepatocellular carcinoma. J Hepatol. 57:794–802. 2012.PubMed/NCBI View Article : Google Scholar

21 

Lucchina N, Tsetis D, Ierardi AM, Giorlando F, Macchi E, Kehagias E, Duka E, Fontana F, Livraghi L and Carrafiello G: Current role of microwave ablation in the treatment of small hepatocellular carcinomas. Ann Gastroenterol. 29:460–465. 2016.PubMed/NCBI View Article : Google Scholar

22 

Dou JP, Yu J, Yang XH, Cheng ZG, Han ZY, Liu FY, Yu XL and Liang P: Outcomes of microwave ablation for hepatocellular carcinoma adjacent to large vessels: A propensity score analysis. Oncotarget. 8:28758–28768. 2017.PubMed/NCBI View Article : Google Scholar

23 

Lubner MG, Brace CL, Hinshaw JL and Lee FT Jr: Microwave tumor ablation: Mechanism of action, clinical results, and devices. J Vasc Inter Radiol. 21 (8 Suppl):S192–S203. 2010.PubMed/NCBI View Article : Google Scholar

24 

Rhim H: Complications of radiofrequency ablation in hepatocellular carcinoma. Abdom Imaging. 30:409–418. 2005.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Suwa K, Seki T, Tsuda R, Yamashina M, Murata M, Yamaguchi T, Nishio A and Okazaki K: Short term treatment results of local ablation with water‑cooled microwave antenna for liver cancer: Comparison with radiofrequency ablation. Mol Clin Oncol 12: 230-236, 2020.
APA
Suwa, K., Seki, T., Tsuda, R., Yamashina, M., Murata, M., Yamaguchi, T. ... Okazaki, K. (2020). Short term treatment results of local ablation with water‑cooled microwave antenna for liver cancer: Comparison with radiofrequency ablation. Molecular and Clinical Oncology, 12, 230-236. https://doi.org/10.3892/mco.2020.1983
MLA
Suwa, K., Seki, T., Tsuda, R., Yamashina, M., Murata, M., Yamaguchi, T., Nishio, A., Okazaki, K."Short term treatment results of local ablation with water‑cooled microwave antenna for liver cancer: Comparison with radiofrequency ablation". Molecular and Clinical Oncology 12.3 (2020): 230-236.
Chicago
Suwa, K., Seki, T., Tsuda, R., Yamashina, M., Murata, M., Yamaguchi, T., Nishio, A., Okazaki, K."Short term treatment results of local ablation with water‑cooled microwave antenna for liver cancer: Comparison with radiofrequency ablation". Molecular and Clinical Oncology 12, no. 3 (2020): 230-236. https://doi.org/10.3892/mco.2020.1983
Copy and paste a formatted citation
x
Spandidos Publications style
Suwa K, Seki T, Tsuda R, Yamashina M, Murata M, Yamaguchi T, Nishio A and Okazaki K: Short term treatment results of local ablation with water‑cooled microwave antenna for liver cancer: Comparison with radiofrequency ablation. Mol Clin Oncol 12: 230-236, 2020.
APA
Suwa, K., Seki, T., Tsuda, R., Yamashina, M., Murata, M., Yamaguchi, T. ... Okazaki, K. (2020). Short term treatment results of local ablation with water‑cooled microwave antenna for liver cancer: Comparison with radiofrequency ablation. Molecular and Clinical Oncology, 12, 230-236. https://doi.org/10.3892/mco.2020.1983
MLA
Suwa, K., Seki, T., Tsuda, R., Yamashina, M., Murata, M., Yamaguchi, T., Nishio, A., Okazaki, K."Short term treatment results of local ablation with water‑cooled microwave antenna for liver cancer: Comparison with radiofrequency ablation". Molecular and Clinical Oncology 12.3 (2020): 230-236.
Chicago
Suwa, K., Seki, T., Tsuda, R., Yamashina, M., Murata, M., Yamaguchi, T., Nishio, A., Okazaki, K."Short term treatment results of local ablation with water‑cooled microwave antenna for liver cancer: Comparison with radiofrequency ablation". Molecular and Clinical Oncology 12, no. 3 (2020): 230-236. https://doi.org/10.3892/mco.2020.1983
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team