Primary adrenal leiomyosarcoma: A case report

Sakellariou,Maria; Dellaportas,Dionysios; Grapsa,Eirini; Tzikanoulas,Menelaos; Dellis,Athanasios; Theodosopoulos,Theodosios; Nastos,Constantinos

doi:10.3892/mco.2020.1987

April-2020 Volume 12 Issue 4

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April-2020 Volume 12 Issue 4

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Case Report

Primary adrenal leiomyosarcoma: A case report

Authors:
- Maria Sakellariou
- Dionysios Dellaportas
- Eirini Grapsa
- Menelaos Tzikanoulas
- Athanasios Dellis
- Theodosios Theodosopoulos
- Constantinos Nastos
View Affiliations / Copyright

Affiliations: Second Department of Surgery, School of Medicine, National and Kapodistrian University of Athens, Aretaieion University Hospital, 11528 Athens, Greece, Department of Nephrology, School of Medicine, National and Kapodistrian University of Athens, Aretaieion University Hospital, 11528 Athens, Greece, Department of Biopathology, School of Medicine, National and Kapodistrian University of Athens, Aretaieion University Hospital, 11528 Athens, Greece
Pages: 317-320
|
Published online on: January 24, 2020

https://doi.org/10.3892/mco.2020.1987
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Abstract

Adrenal leiomyosarcomas are rare mesenchymal tumors of the suprarenal region that are usually diagnosed after they have reached a large size. We report the case of a 62‑year‑old male with an incidentally found left adrenal mass. Magnetic resonance imaging of the retroperitoneal space showed a heterogeneously enhanced mass, measuring 10x8.2 cm, with characteristics suspicious of malignancy. The patient underwent left radical adrenalectomy after the hormonal evaluation of the tumor due to the high probability of adrenocortical carcinoma. However, microscopic examination of the tumor showed a spindle cell sarcoma. Immunohistochemically the neoplastic cells were found positive for desmin and smooth muscle actin and the diagnosis of a well differentiated adrenal leiomyosarcoma was established. During follow‑up the patient presented an aggressive course as he developed bone, liver and pulmonary metastases early postoperatively, which were treated with radiation therapy and chemotherapy. The patient has progressive metastatic disease while on chemotherapy 31 months after surgery.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Primary adrenal leiomyosarcoma: A case report

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Abstract

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