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The presence of chronic diseases contributes to the occurrence risk factors for gynecological cancers in Japan

  • Authors:
    • Kazuhiro Okamoto
    • Keiichiro Nakamura
    • Hirofumi Matsuoka
    • Yuko Matsubara
    • Junko Haraga
    • Chikako Ogawa
    • Hisashi Masuyama
  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Okayama 700‑8558, Japan
    Copyright: © Okamoto et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 336-342
    |
    Published online on: January 29, 2020
       https://doi.org/10.3892/mco.2020.1989
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Abstract

The aim of the present study was to determine whether chronic diseases (CD), such as hypertension, diabetes mellitus, dyslipidemia, heart diseases and cerebrovascular diseases, are occurrence risk factors and affect the survival of patients with gynecological cancers (GC). The correlations between CD and the characteristics and survival of 1,590 GC patients [685 with cervical cancer (CC), 613 with endometrial cancer (EM) and 292 with ovarian cancer (OV)] were investigated in the present study. Of the CD patients, 189 had CC (27.6%), 265 had EM (43.2%) and 72 had OV (24.7%). The incidence of CD increased with age in GC patients. The number of CD patients aged ≥70 years, was 8.6‑fold higher in the CC group, 3.0‑fold higher in the EM group, and 9.6‑fold higher in the OV group compared with those aged <50 years. CD and excess body weight were associated with GC regardless of patient age. However, there was no correlation between CD and survival at any age in GC patients. These findings indicate that CD contribute to >24% of the occurrence risk factors in GC patients in Japan.
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Copy and paste a formatted citation
Spandidos Publications style
Okamoto K, Nakamura K, Matsuoka H, Matsubara Y, Haraga J, Ogawa C and Masuyama H: The presence of chronic diseases contributes to the occurrence risk factors for gynecological cancers in Japan. Mol Clin Oncol 12: 336-342, 2020.
APA
Okamoto, K., Nakamura, K., Matsuoka, H., Matsubara, Y., Haraga, J., Ogawa, C., & Masuyama, H. (2020). The presence of chronic diseases contributes to the occurrence risk factors for gynecological cancers in Japan. Molecular and Clinical Oncology, 12, 336-342. https://doi.org/10.3892/mco.2020.1989
MLA
Okamoto, K., Nakamura, K., Matsuoka, H., Matsubara, Y., Haraga, J., Ogawa, C., Masuyama, H."The presence of chronic diseases contributes to the occurrence risk factors for gynecological cancers in Japan". Molecular and Clinical Oncology 12.4 (2020): 336-342.
Chicago
Okamoto, K., Nakamura, K., Matsuoka, H., Matsubara, Y., Haraga, J., Ogawa, C., Masuyama, H."The presence of chronic diseases contributes to the occurrence risk factors for gynecological cancers in Japan". Molecular and Clinical Oncology 12, no. 4 (2020): 336-342. https://doi.org/10.3892/mco.2020.1989
Copy and paste a formatted citation
x
Spandidos Publications style
Okamoto K, Nakamura K, Matsuoka H, Matsubara Y, Haraga J, Ogawa C and Masuyama H: The presence of chronic diseases contributes to the occurrence risk factors for gynecological cancers in Japan. Mol Clin Oncol 12: 336-342, 2020.
APA
Okamoto, K., Nakamura, K., Matsuoka, H., Matsubara, Y., Haraga, J., Ogawa, C., & Masuyama, H. (2020). The presence of chronic diseases contributes to the occurrence risk factors for gynecological cancers in Japan. Molecular and Clinical Oncology, 12, 336-342. https://doi.org/10.3892/mco.2020.1989
MLA
Okamoto, K., Nakamura, K., Matsuoka, H., Matsubara, Y., Haraga, J., Ogawa, C., Masuyama, H."The presence of chronic diseases contributes to the occurrence risk factors for gynecological cancers in Japan". Molecular and Clinical Oncology 12.4 (2020): 336-342.
Chicago
Okamoto, K., Nakamura, K., Matsuoka, H., Matsubara, Y., Haraga, J., Ogawa, C., Masuyama, H."The presence of chronic diseases contributes to the occurrence risk factors for gynecological cancers in Japan". Molecular and Clinical Oncology 12, no. 4 (2020): 336-342. https://doi.org/10.3892/mco.2020.1989
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