Photohyperthermal therapy using liposomally formulated indocyanine green for feline nasal lymphoma: A case report

  • Authors:
    • Masamichi Yamashita
    • Mayumi Mayama
    • Akiko Suganami
    • Kazuo Azuma
    • Takeshi  Tsuka
    • Norihiko Ito
    • Tomohiro Imagawa
    • Yutaka Tamura
    • Yoshiharu Okamoto
  • View Affiliations

  • Published online on: July 31, 2020     https://doi.org/10.3892/mco.2020.2107
  • Article Number: 37
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Abstract

Our previous research has focused on the development of a novel cancer therapy by using photohyperthermal therapy (PHT) with indocyanine green (ICG) as an optical sensitizer. ICG‑Lipo is a liposomally formulated ICG derivative in which ICG is tagged with an octadeca‑alkyl chain to incorporate into liposome bilayers, and contains antitumor drugs such as carboplatin and paclitaxel within the inner membrane space. The present study reported a case of feline nasal lymphoma that was treated with combination therapy of PHT with ICG‑Lipo. An antitumour effect was observed, and the patient entered remission. Complications from the radiation treatment included skin burns and bleeding from the irradiated hard palate. Serious side effects related to the drugs were not observed. This report suggested that PHT using ICG‑Lipo enabled efficient and safe treatment of lymphoma, and that treatment with a liposomal drug delivery system was enhanced by PHT.
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October-2020
Volume 13 Issue 4

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Spandidos Publications style
Yamashita M, Mayama M, Suganami A, Azuma K, Tsuka T, Ito N, Imagawa T, Tamura Y and Okamoto Y: Photohyperthermal therapy using liposomally formulated indocyanine green for feline nasal lymphoma: A case report. Mol Clin Oncol 13: 37, 2020
APA
Yamashita, M., Mayama, M., Suganami, A., Azuma, K., Tsuka, T., Ito, N. ... Okamoto, Y. (2020). Photohyperthermal therapy using liposomally formulated indocyanine green for feline nasal lymphoma: A case report. Molecular and Clinical Oncology, 13, 37. https://doi.org/10.3892/mco.2020.2107
MLA
Yamashita, M., Mayama, M., Suganami, A., Azuma, K., Tsuka, T., Ito, N., Imagawa, T., Tamura, Y., Okamoto, Y."Photohyperthermal therapy using liposomally formulated indocyanine green for feline nasal lymphoma: A case report". Molecular and Clinical Oncology 13.4 (2020): 37.
Chicago
Yamashita, M., Mayama, M., Suganami, A., Azuma, K., Tsuka, T., Ito, N., Imagawa, T., Tamura, Y., Okamoto, Y."Photohyperthermal therapy using liposomally formulated indocyanine green for feline nasal lymphoma: A case report". Molecular and Clinical Oncology 13, no. 4 (2020): 37. https://doi.org/10.3892/mco.2020.2107