Dermatofibrosarcoma protuberans associated with trauma: A case report

  • Authors:
    • Robyn Cabral
    • Matthaus Wilford
    • Michael J. Ramdass
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  • Published online on: August 20, 2020     https://doi.org/10.3892/mco.2020.2121
  • Article Number: 51
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Abstract

A case of dermatofibrosarcoma protuberans (DFSP) in a 22‑year old female associated with blunt trauma of the mid‑upper back is presented in the current study with a review of the literature. DFSP is a rare slow growing sarcoma of the soft tissue most commonly seen on the trunk and upper extremities with a low to intermediate grade malignant potential, high chance of local invasion and a high local recurrence rate. The literature search revealed that both non‑congenital mutation as well as trauma serve a role in the development of this dermal neoplasm, but the exact mechanism by which trauma may predispose to development of DFSP is unknown. However, it seems intuitive that chronic inflammation and stimulation of the immune system at a local level may trigger the immunopathologic changes that could lead to the malignant transformation of dermal cells. Future research into the relationship between trauma and DFSP on a cellular level is required, as there appears to be a direct link present.

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November-2020
Volume 13 Issue 5

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Spandidos Publications style
Cabral R, Wilford M and Ramdass MJ: Dermatofibrosarcoma protuberans associated with trauma: A case report. Mol Clin Oncol 13: 51, 2020
APA
Cabral, R., Wilford, M., & Ramdass, M.J. (2020). Dermatofibrosarcoma protuberans associated with trauma: A case report. Molecular and Clinical Oncology, 13, 51. https://doi.org/10.3892/mco.2020.2121
MLA
Cabral, R., Wilford, M., Ramdass, M. J."Dermatofibrosarcoma protuberans associated with trauma: A case report". Molecular and Clinical Oncology 13.5 (2020): 51.
Chicago
Cabral, R., Wilford, M., Ramdass, M. J."Dermatofibrosarcoma protuberans associated with trauma: A case report". Molecular and Clinical Oncology 13, no. 5 (2020): 51. https://doi.org/10.3892/mco.2020.2121