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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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March-2021 Volume 14 Issue 3

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Intramedullary spinal cord metastasis of malignant melanoma:Two cases with rim signs in contrast‑enhanced magnetic resonance imaging: A case report

  • Authors:
    • Haruki Mizuta
    • Kenjiro Namikawa
    • Kenta Nakama
    • Naoya Yamazaki

  • View Affiliations / Copyright

    Affiliations: Department of Dermatologic Oncology, National Cancer Center Hospital, Tokyo 104‑0045, Japan
    Copyright: © Mizuta et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 47
    |
    Published online on: January 14, 2021
       https://doi.org/10.3892/mco.2021.2209
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Abstract

Spinal cord metastasis of malignant melanoma is mostly caused by the invasion of the spinal cord by malignant melanoma. However, direct metastasis in the spinal cord is rare and difficult to diagnose accurately. A few diagnostically valuable findings of intramedullary spinal cord metastases (ISCMs) have been published. However, a highly specific finding of ISCMs of all carcinomas is the ‘rim sign’, which signifies the enhancement of the edge‑dominant effect of the lesion in contrast‑enhanced MRI. The objective of this case series was to examine the ratio of ISCMs of malignant melanoma with an indication of rim signs in contrast‑enhanced MRI. The present report describes two cases of ISCMs of malignant melanoma in which the rim sign in contrast‑enhanced MRI was useful for diagnosis.
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Copy and paste a formatted citation
Spandidos Publications style
Mizuta H, Namikawa K, Nakama K and Yamazaki N: Intramedullary spinal cord metastasis of malignant melanoma:Two cases with rim signs in contrast‑enhanced magnetic resonance imaging: A case report. Mol Clin Oncol 14: 47, 2021.
APA
Mizuta, H., Namikawa, K., Nakama, K., & Yamazaki, N. (2021). Intramedullary spinal cord metastasis of malignant melanoma:Two cases with rim signs in contrast‑enhanced magnetic resonance imaging: A case report. Molecular and Clinical Oncology, 14, 47. https://doi.org/10.3892/mco.2021.2209
MLA
Mizuta, H., Namikawa, K., Nakama, K., Yamazaki, N."Intramedullary spinal cord metastasis of malignant melanoma:Two cases with rim signs in contrast‑enhanced magnetic resonance imaging: A case report". Molecular and Clinical Oncology 14.3 (2021): 47.
Chicago
Mizuta, H., Namikawa, K., Nakama, K., Yamazaki, N."Intramedullary spinal cord metastasis of malignant melanoma:Two cases with rim signs in contrast‑enhanced magnetic resonance imaging: A case report". Molecular and Clinical Oncology 14, no. 3 (2021): 47. https://doi.org/10.3892/mco.2021.2209
Copy and paste a formatted citation
x
Spandidos Publications style
Mizuta H, Namikawa K, Nakama K and Yamazaki N: Intramedullary spinal cord metastasis of malignant melanoma:Two cases with rim signs in contrast‑enhanced magnetic resonance imaging: A case report. Mol Clin Oncol 14: 47, 2021.
APA
Mizuta, H., Namikawa, K., Nakama, K., & Yamazaki, N. (2021). Intramedullary spinal cord metastasis of malignant melanoma:Two cases with rim signs in contrast‑enhanced magnetic resonance imaging: A case report. Molecular and Clinical Oncology, 14, 47. https://doi.org/10.3892/mco.2021.2209
MLA
Mizuta, H., Namikawa, K., Nakama, K., Yamazaki, N."Intramedullary spinal cord metastasis of malignant melanoma:Two cases with rim signs in contrast‑enhanced magnetic resonance imaging: A case report". Molecular and Clinical Oncology 14.3 (2021): 47.
Chicago
Mizuta, H., Namikawa, K., Nakama, K., Yamazaki, N."Intramedullary spinal cord metastasis of malignant melanoma:Two cases with rim signs in contrast‑enhanced magnetic resonance imaging: A case report". Molecular and Clinical Oncology 14, no. 3 (2021): 47. https://doi.org/10.3892/mco.2021.2209
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