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Article

Dermatofibrosarcoma protuberans of the breast: A case study

  • Authors:
    • Dionysios Dimas
    • Ioannis Boutas
    • Anastasios Potiris
    • Nektarios Koufopoulos
    • Dimitrios Balalis
    • Kyparissia Sitara
    • Fotios Danglis
    • Ioannis Misitzis
  • View Affiliations / Copyright

    Affiliations: Breast Unit, Athens Medical Center, Psychiko Clinic, Athens 11525, Greece, Third Department of Obstetrics and Gynecology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens 12462, Greece, Second Department of Pathology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens 12462, Greece, Department of Surgery, Saint Savvas Anti‑Cancer Hospital, Athens 11521, Greece, Surgical Pathology Department, National and Kapodistrian University of Athens, Athens 15125, Greece
  • Article Number: 50
    |
    Published online on: January 20, 2021
       https://doi.org/10.3892/mco.2021.2212
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Abstract

Dermatofibrosarcoma protuberans (DFSP) is a superficial mesenchymal neoplasm that originates from the dermal fibroblasts and tends to be locally aggressive. Although infrequent, it is one of the most common cutaneous sarcomas. It mainly affects young and middle‑aged patients 20 to 50 years old. Any area of skin may be involved, but the most common sites of presentation are the trunk and extremities. DFSP of the breast is extremely rare. It classically presents as a nodular, exophytic, cutaneous mass, though initially it can manifest as a flat plague and can show persistent but slow growth for many years. Due to increased risk of local recurrence, the standard of care for localized disease is surgical excision with adequate margins. Wide local excision is the most common technique used, but as an alternative Mohs micrographic surgery has emerged as a procedure that offers lower local recurrence rates. Metastases are rare but have been previously reported. In such patients, treatment with imatinib or radiotherapy can be considered. The current case presents a 52‑year‑old lady with DFSP of the breast that was successfully managed by the Breast Unit of Athens Medical Center‑Psychiko Clinic.
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Copy and paste a formatted citation
Spandidos Publications style
Dimas D, Boutas I, Potiris A, Koufopoulos N, Balalis D, Sitara K, Danglis F and Misitzis I: Dermatofibrosarcoma protuberans of the breast: A case study. Mol Clin Oncol 14: 50, 2021.
APA
Dimas, D., Boutas, I., Potiris, A., Koufopoulos, N., Balalis, D., Sitara, K. ... Misitzis, I. (2021). Dermatofibrosarcoma protuberans of the breast: A case study. Molecular and Clinical Oncology, 14, 50. https://doi.org/10.3892/mco.2021.2212
MLA
Dimas, D., Boutas, I., Potiris, A., Koufopoulos, N., Balalis, D., Sitara, K., Danglis, F., Misitzis, I."Dermatofibrosarcoma protuberans of the breast: A case study". Molecular and Clinical Oncology 14.3 (2021): 50.
Chicago
Dimas, D., Boutas, I., Potiris, A., Koufopoulos, N., Balalis, D., Sitara, K., Danglis, F., Misitzis, I."Dermatofibrosarcoma protuberans of the breast: A case study". Molecular and Clinical Oncology 14, no. 3 (2021): 50. https://doi.org/10.3892/mco.2021.2212
Copy and paste a formatted citation
x
Spandidos Publications style
Dimas D, Boutas I, Potiris A, Koufopoulos N, Balalis D, Sitara K, Danglis F and Misitzis I: Dermatofibrosarcoma protuberans of the breast: A case study. Mol Clin Oncol 14: 50, 2021.
APA
Dimas, D., Boutas, I., Potiris, A., Koufopoulos, N., Balalis, D., Sitara, K. ... Misitzis, I. (2021). Dermatofibrosarcoma protuberans of the breast: A case study. Molecular and Clinical Oncology, 14, 50. https://doi.org/10.3892/mco.2021.2212
MLA
Dimas, D., Boutas, I., Potiris, A., Koufopoulos, N., Balalis, D., Sitara, K., Danglis, F., Misitzis, I."Dermatofibrosarcoma protuberans of the breast: A case study". Molecular and Clinical Oncology 14.3 (2021): 50.
Chicago
Dimas, D., Boutas, I., Potiris, A., Koufopoulos, N., Balalis, D., Sitara, K., Danglis, F., Misitzis, I."Dermatofibrosarcoma protuberans of the breast: A case study". Molecular and Clinical Oncology 14, no. 3 (2021): 50. https://doi.org/10.3892/mco.2021.2212
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