The tuberous sclerosis complex‑associated giant renal angiomyolipoma: A case report

Sun,Pengfei; Chen,Shuangxing; Su,Zhengming; He,Yongzhong

doi:10.3892/mco.2021.2214

The tuberous sclerosis complex‑associated giant renal angiomyolipoma: A case report

Authors:
- Pengfei Sun
- Shuangxing Chen
- Zhengming Su
- Yongzhong He
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Affiliations: Department of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510700, P.R. China
Published online on: January 21, 2021 https://doi.org/10.3892/mco.2021.2214
Article Number: 52
Copyright: © Sun et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Renal angiomyolipoma (RAML), also referred to as renal hamartoma, is a rare benign tumor. There are two types of RAML, which include the tuberous sclerosis complex (TSC)‑associated type and the sporadic type. TSC is an autosomal dominant genetic disease characterized by the growth of benign tumors in the skin, brain, kidneys, lung and heart. TSC leads to organ dysfunction, as the normal parenchyma is replaced by a variety of cell types. The current study presents a case of giant RAML in a 20‑year‑old female, who was hospitalized for epileptic seizures. Large abdominal lesions were detected during hospitalization. Subsequently, she underwent open mass resection and right kidney partial resection. Postoperative pathological examination confirmed that the mass was angiomyolipoma.

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