Open Access

Postoperative solitary liver metastasis from esophageal squamous cell carcinoma achieving a clinical complete response to chemotherapy with cisplatin and 5‑fluorouracil followed by stereotactic body radiotherapy: A case report

  • Authors:
    • Shuichi Fukuda
    • Kaoru Okajima
    • Kaoru Okada
    • Kohei Fukuda
    • Tomoko Wakasa
    • Tomoyuki Tsujimoto
    • Atsushi Gakuhara
    • Hideo Tomihara
    • Katsuya Ohta
    • Kotaro Kitani
    • Kazuhiko Hashimoto
    • Hajime Ishikawa
    • Jin-Ichi Hida
    • Masao Yukawa
    • Yoshio Ohta
    • Masatoshi Inoue
  • View Affiliations

  • Published online on: May 7, 2021     https://doi.org/10.3892/mco.2021.2292
  • Article Number: 130
  • Copyright: © Fukuda et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Treatment strategies for distant organ metastasis have changed markedly since the concept of oligometastasis was introduced. The perception that distant organ metastasis is a systemic disease and not eligible for local therapy is now a thing of the past. Therefore, the present report details a case of postoperative solitary liver metastasis from esophageal squamous cell carcinoma (ESCC), which achieved a clinical complete response to chemotherapy with cisplatin and 5‑fluorouracil (5‑FU) followed by stereotactic body radiotherapy (SBRT). A 76‑year‑old male patient underwent esophagectomy for lower thoracic ESCC. At 7 months after surgery, abdominal CT revealed a solitary hypovascular mass, 28 mm in size, in segment 7 of the liver. After three courses of chemotherapy with cisplatin and 5‑FU, abdominal CT revealed that the liver mass had shrunk to 7 mm in size. SBRT was then administered with a 6 MV X‑ray beam generated by a linear accelerator. A total dose of 50 Gy was given in 5 fractions of 10 Gy to the liver mass. At 1 month after SBRT, abdominal CT revealed that the liver mass had disappeared. The patient received no further adjuvant chemotherapy and had no recurrence at 18 months after diagnosis of liver metastasis and 13 months after SBRT.
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July-2021
Volume 15 Issue 1

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Spandidos Publications style
Fukuda S, Okajima K, Okada K, Fukuda K, Wakasa T, Tsujimoto T, Gakuhara A, Tomihara H, Ohta K, Kitani K, Kitani K, et al: Postoperative solitary liver metastasis from esophageal squamous cell carcinoma achieving a clinical complete response to chemotherapy with cisplatin and 5‑fluorouracil followed by stereotactic body radiotherapy: A case report. Mol Clin Oncol 15: 130, 2021
APA
Fukuda, S., Okajima, K., Okada, K., Fukuda, K., Wakasa, T., Tsujimoto, T. ... Inoue, M. (2021). Postoperative solitary liver metastasis from esophageal squamous cell carcinoma achieving a clinical complete response to chemotherapy with cisplatin and 5‑fluorouracil followed by stereotactic body radiotherapy: A case report. Molecular and Clinical Oncology, 15, 130. https://doi.org/10.3892/mco.2021.2292
MLA
Fukuda, S., Okajima, K., Okada, K., Fukuda, K., Wakasa, T., Tsujimoto, T., Gakuhara, A., Tomihara, H., Ohta, K., Kitani, K., Hashimoto, K., Ishikawa, H., Hida, J., Yukawa, M., Ohta, Y., Inoue, M."Postoperative solitary liver metastasis from esophageal squamous cell carcinoma achieving a clinical complete response to chemotherapy with cisplatin and 5‑fluorouracil followed by stereotactic body radiotherapy: A case report". Molecular and Clinical Oncology 15.1 (2021): 130.
Chicago
Fukuda, S., Okajima, K., Okada, K., Fukuda, K., Wakasa, T., Tsujimoto, T., Gakuhara, A., Tomihara, H., Ohta, K., Kitani, K., Hashimoto, K., Ishikawa, H., Hida, J., Yukawa, M., Ohta, Y., Inoue, M."Postoperative solitary liver metastasis from esophageal squamous cell carcinoma achieving a clinical complete response to chemotherapy with cisplatin and 5‑fluorouracil followed by stereotactic body radiotherapy: A case report". Molecular and Clinical Oncology 15, no. 1 (2021): 130. https://doi.org/10.3892/mco.2021.2292