Pathological examination of a placenta leading to the diagnosis of endometrial carcinoma: A case report
- Authors:
- Takaaki Maeda
- Masato Nishimura
- Eishi Sogawa
- Takashi Kaji
- Minoru Irahara
- Takeshi Iwasa
View Affiliations
Affiliations: Department of Obstetrics and Gynecology, Tokushima University Hospital, Tokushima 770‑8503, Japan
- Published online on: December 1, 2021 https://doi.org/10.3892/mco.2021.2457
-
Article Number:
24
-
Copyright: © Maeda
et al. This is an open access article distributed under the
terms of Creative
Commons Attribution License.
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Abstract
Although endometrial cancer is extremely rare during pregnancy, the placental metastasis of endometrial cancer is even rarer. The current study presents a case of endometrial carcinoma that was diagnosed through the pathological examination of the placenta. A 35‑year‑old primipara woman who underwent frozen‑thawed embryo transfer at the Keiai Ladies Clinic in Tokushima prefecture (Japan) received regular prenatal check‑ups. She was transferred to Tokushima University Hospital for perinatal management due to the preterm premature rupture of membranes at 21 weeks and 6 days gestation. The administration of antibiotics and tocolytic agents was continued; however, labor pain occurred at 23 weeks and 3 days gestation, and a female fetus weighing 524 g was delivered vaginally. The placenta weighed 262 g and had no macroscopic abnormalities. It was submitted for pathological examination, which revealed metastatic adenocarcinoma (clear cell carcinoma suspected). The patient was subsequently diagnosed with endometrial cancer (stage Ⅰ suspected), and underwent abdominal total hysterectomy, bilateral salpingo‑oophorectomy, partial omentectomy and pelvic lymph node dissection. The final diagnosis was stage IA endometrial cancer (endometrioid carcinoma, G2). At 1 year after surgery, there was no evidence of disease. The present case highlights the importance of considering the emergence of endometrial cancer during pregnancy.
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