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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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March-2022 Volume 16 Issue 3

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International Journal of Molecular Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Case Report

Cervical dissecting extravasation of oxaliplatin: A case report

  • Authors:
    • Jorge Hernando
    • Judit Riera‑Arnau
    • Maria Roca
    • Alejandro Garcia
    • Jaume Capdevila
  • View Affiliations / Copyright

    Affiliations: Gastrointestinal and Endocrine Tumors Unit, Department of Medical Oncology, Vall d'Hebron Institute of Oncology, Autonomous University of Barcelona, 08035 Barcelona, Spain, Clinical Pharmacology Service, Department of Pharmacovigilance and Pharmacoepidemiology, Vall d'Hebron University Hospital, Autonomous University of Barcelona, 08035 Barcelona, Spain
  • Article Number: 60
    |
    Published online on: January 12, 2022
       https://doi.org/10.3892/mco.2022.2493
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Abstract

Oxaliplatin is a chemotherapy drug considered to be an irritant and vesicant. Peripheral extravasation could happen following oxaliplatin chemotherapy administration, but mediastinal or cervical events are rare. The present study focused on the case of a 64‑year‑old female patient with KRAS‑mutated colorectal adenocarcinoma. The patient was prescribed folinic acid, fluorouracil and oxaliplatin chemotherapy via a subcutaneous pump or port‑a‑cath device, which was inserted into the right subclavian vein. The patient reported a sudden throbbing pain in the chest wall and anterior cervical region. After performing a computed tomography scan, anterior cervical collection and jugular‑subclavian venous confluence at the distal end was observed at the venous access site of the subcutaneous port‑a‑cath device, which extended cranially, dissected cervical planes and forming a hydro‑aerial collection in the submaxillary region. Subsequently, the port‑a‑cath device was removed and a warm dry compress was applied. After 2 weeks, the patient had fully recovered without any sequelae at the cervical level. To the best of the authors' knowledge, this is the first case of cervical extravasation of oxaliplatin reported in the literature to date and will help to manage similar situations.
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Copy and paste a formatted citation
Spandidos Publications style
Hernando J, Riera‑Arnau J, Roca M, Garcia A and Capdevila J: Cervical dissecting extravasation of oxaliplatin: A case report. Mol Clin Oncol 16: 60, 2022.
APA
Hernando, J., Riera‑Arnau, J., Roca, M., Garcia, A., & Capdevila, J. (2022). Cervical dissecting extravasation of oxaliplatin: A case report. Molecular and Clinical Oncology, 16, 60. https://doi.org/10.3892/mco.2022.2493
MLA
Hernando, J., Riera‑Arnau, J., Roca, M., Garcia, A., Capdevila, J."Cervical dissecting extravasation of oxaliplatin: A case report". Molecular and Clinical Oncology 16.3 (2022): 60.
Chicago
Hernando, J., Riera‑Arnau, J., Roca, M., Garcia, A., Capdevila, J."Cervical dissecting extravasation of oxaliplatin: A case report". Molecular and Clinical Oncology 16, no. 3 (2022): 60. https://doi.org/10.3892/mco.2022.2493
Copy and paste a formatted citation
x
Spandidos Publications style
Hernando J, Riera‑Arnau J, Roca M, Garcia A and Capdevila J: Cervical dissecting extravasation of oxaliplatin: A case report. Mol Clin Oncol 16: 60, 2022.
APA
Hernando, J., Riera‑Arnau, J., Roca, M., Garcia, A., & Capdevila, J. (2022). Cervical dissecting extravasation of oxaliplatin: A case report. Molecular and Clinical Oncology, 16, 60. https://doi.org/10.3892/mco.2022.2493
MLA
Hernando, J., Riera‑Arnau, J., Roca, M., Garcia, A., Capdevila, J."Cervical dissecting extravasation of oxaliplatin: A case report". Molecular and Clinical Oncology 16.3 (2022): 60.
Chicago
Hernando, J., Riera‑Arnau, J., Roca, M., Garcia, A., Capdevila, J."Cervical dissecting extravasation of oxaliplatin: A case report". Molecular and Clinical Oncology 16, no. 3 (2022): 60. https://doi.org/10.3892/mco.2022.2493
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