Primary non‑Hodgkin lymphoma of the extra‑hepatic bile duct: A case report

Pararas,Nikolaos; Foukas,Periklis G.; Pikoulis,Andreas; Bagias,George; Papakonstantinou,Dimitris; Pappa,Vassiliki; Nastos,Konstantinos; Pikoulis,Emmanouil

doi:10.3892/mco.2022.2548

Primary non‑Hodgkin lymphoma of the extra‑hepatic bile duct: A case report

Authors:
- Nikolaos Pararas
- Periklis G. Foukas
- Andreas Pikoulis
- George Bagias
- Dimitris Papakonstantinou
- Vassiliki Pappa
- Konstantinos Nastos
- Emmanouil Pikoulis
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Affiliations: Surgical Department, Dr Sulaiman Al Habib Hospital, Riyadh 12987, Saudi Arabia, Second Department of Pathology, National and Kapodistrian University of Athens, Attikon University Hospital, 12462 Athens, Greece, Third Department of Surgery, National and Kapodistrian University of Athens, Attikon University Hospital, 12462 Athens, Greece, Hematology Unit, Second Propaedeutic Department of Internal Medicine and Research Institute, School of Medicine, National and Kapodistrian University of Athens, Attikon University Hospital, 12462 Athens, Greece
Published online on: May 25, 2022 https://doi.org/10.3892/mco.2022.2548
Article Number: 115
Copyright: © Pararas et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Lymphoma is known to be a systemic lymphoproliferative malignancy, which is divided into two subtypes: Hodgkin lymphoma and non‑Hodgkin lymphoma. Non‑Hodgkin lymphoma originates from nodal and extranodal sites. In the staging of non‑Hodgkin lymphoma, the liver is implicated in 40% of cases; however, primary liver non‑Hodgkin lymphoma represents <1% of all non‑Hodgkin lymphoma cases. Because of its rarity, it is not usually considered in the differential diagnosis of patients that present with jaundice. Since the first case of primary non‑Hodgkin lymphoma of the extra‑hepatic bile ducts was presented, only 42 similar cases have been reported in the English literature. The present case report describes a rare case of non‑Hodgkin lymphoma of the common hepatic duct, which presented with obstructive jaundice and represented a complex differential diagnostic issue.

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