Synchronous colon cancer after treatment for rectal follicular lymphoma: A case report

Saito,Makoto; Egami,Hiroki; Kato,Takashi; Yokoyama,Emi; Izumiyama,Koh; Mori,Akio; Morioka,Masanobu; Kondo,Takeshi; Tanei,Zen-Ichi

doi:10.3892/mco.2022.2562

August-2022 Volume 17 Issue 2

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August-2022 Volume 17 Issue 2

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Case Report Open Access

Synchronous colon cancer after treatment for rectal follicular lymphoma: A case report

Authors:
- Makoto Saito
- Hiroki Egami
- Takashi Kato
- Emi Yokoyama
- Koh Izumiyama
- Akio Mori
- Masanobu Morioka
- Takeshi Kondo
- Zen-Ichi Tanei
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Affiliations: Blood Disorders Center, Aiiku Hospital, Sapporo, Hokkaido 064‑0804, Japan, Department of Gastroenterology, Aiiku Hospital, Sapporo, Hokkaido 064‑0804, Japan, Department of Cancer Pathology, Faculty of Medicine, Hokkaido University, Sapporo, Hokkaido 060‑8638, Japan

Copyright: © Saito et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Article Number: 129
|
Published online on: June 21, 2022

https://doi.org/10.3892/mco.2022.2562
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Abstract

Colorectal follicular lymphoma (FL) is rare. In addition, it is even rarer that colon cancer develops synchronously with colorectal lymphoma. The present study reports a case of sigmoid colon cancer that developed 6 months after endoscopic resection of rectal FL. A 71‑year‑old man with a history of developing mucosa‑associated lymphoid tissue lymphoma in his stomach at age 48, right neck region at age 59 (the latter later modified as FL) and lung adenocarcinoma at age 60 now suffers from rectal FL. Endoscopic submucosal dissection (ESD) was performed at our hospital (Aiiku Hospital), and 6 months after the treatment, sigmoid colon cancer was confirmed by colonoscopy for the follow‑up study. The patient was successfully curatively resected by ESD plus local resection and has survived without a recurrence for >3 years with no treatment. It was speculated that in the present case, cancer‑related genes were changed as a carcinogenic mechanism due to decreased immune function associated with the onset of lymphoma.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Synchronous colon cancer after treatment for rectal follicular lymphoma: A case report

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