Open Access

Pancreaticoduodenectomy as a feasible choice for periampullary malignancy in octogenarians

  • Authors:
    • Stavros Parasyris
    • Ioannis Hatzaras
    • Vasiliki Ntella
    • Theodoros Sidiropoulos
    • Ioannis Margaris
    • Nikos Pantazis
    • Panagiotis Kokoropoulos
    • Panteleimon Vassiliu
    • Paraskevi Matsota
    • Vasileios Smyrniotis
    • Nikolaos Arkadopoulos
  • View Affiliations

  • Published online on: August 17, 2022     https://doi.org/10.3892/mco.2022.2581
  • Article Number: 148
  • Copyright: © Parasyris et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The efficacy and safety of pancreaticoduodenectomy (PD) has not been yet studied in octogenarians in Greece. The present study reviewed records of all consecutive patients that underwent PD at the 4th Surgical Department of Attikon University Hospital (Athens, Greece) between January 1st, 2010 and December 31st, 2019. Differences between two age groups (group Y <80 years; group O >80 years) were analyzed. Study endpoints were length of stay, overall morbidity, 30‑day mortality and overall survival (OS). There were 198 patients in Group Y (mean age, 65 years) and 20 patients in Group O (mean age, 82 years). Octogenarians had worse American Society of Anesthesiology score (>2; 31.3 vs. 65%; P=0.018). Median stay was not significantly different between the two groups (14 days vs. 16 days; P=0.307), neither was the 30‑day mortality (6.1 vs. 5.0%; P>0.99). Median OS was similar between the two groups (35 months vs. 28 months; P=0.577). In a tertiary center in Greece, morbidity and mortality rates after PD were similar between the two groups. Patients should not be denied a PD, solely based on advanced age.

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October-2022
Volume 17 Issue 4

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Spandidos Publications style
Parasyris S, Hatzaras I, Ntella V, Sidiropoulos T, Margaris I, Pantazis N, Kokoropoulos P, Vassiliu P, Matsota P, Smyrniotis V, Smyrniotis V, et al: Pancreaticoduodenectomy as a feasible choice for periampullary malignancy in octogenarians. Mol Clin Oncol 17: 148, 2022
APA
Parasyris, S., Hatzaras, I., Ntella, V., Sidiropoulos, T., Margaris, I., Pantazis, N. ... Arkadopoulos, N. (2022). Pancreaticoduodenectomy as a feasible choice for periampullary malignancy in octogenarians. Molecular and Clinical Oncology, 17, 148. https://doi.org/10.3892/mco.2022.2581
MLA
Parasyris, S., Hatzaras, I., Ntella, V., Sidiropoulos, T., Margaris, I., Pantazis, N., Kokoropoulos, P., Vassiliu, P., Matsota, P., Smyrniotis, V., Arkadopoulos, N."Pancreaticoduodenectomy as a feasible choice for periampullary malignancy in octogenarians". Molecular and Clinical Oncology 17.4 (2022): 148.
Chicago
Parasyris, S., Hatzaras, I., Ntella, V., Sidiropoulos, T., Margaris, I., Pantazis, N., Kokoropoulos, P., Vassiliu, P., Matsota, P., Smyrniotis, V., Arkadopoulos, N."Pancreaticoduodenectomy as a feasible choice for periampullary malignancy in octogenarians". Molecular and Clinical Oncology 17, no. 4 (2022): 148. https://doi.org/10.3892/mco.2022.2581